SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q4n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 166
GLY A 109
 None
 1.32A 1kifA-3q4nA:
undetectable		 1kifA-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 174
GLY A 109
 None
 1.16A 1kifA-3q4nA:
undetectable		 1kifA-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 166
GLY A 109
 None
 1.32A 1kifB-3q4nA:
undetectable		 1kifB-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 174
GLY A 109
 None
 1.16A 1kifB-3q4nA:
undetectable		 1kifB-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 166
GLY A 109
 None
 1.32A 1kifC-3q4nA:
undetectable		 1kifC-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 174
GLY A 109
 None
 1.16A 1kifC-3q4nA:
undetectable		 1kifC-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 166
GLY A 109
 None
 1.32A 1kifD-3q4nA:
undetectable		 1kifD-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 174
GLY A 109
 None
 1.16A 1kifD-3q4nA:
undetectable		 1kifD-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 166
GLY A 109
 None
 1.32A 1kifE-3q4nA:
undetectable		 1kifE-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 174
GLY A 109
 None
 1.16A 1kifE-3q4nA:
undetectable		 1kifE-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 166
GLY A 109
 None
 1.32A 1kifF-3q4nA:
undetectable		 1kifF-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 174
GLY A 109
 None
 1.16A 1kifF-3q4nA:
undetectable		 1kifF-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 166
GLY A 109
 None
 1.32A 1kifG-3q4nA:
undetectable		 1kifG-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 174
GLY A 109
 None
 1.16A 1kifG-3q4nA:
undetectable		 1kifG-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 166
GLY A 109
 None
 1.32A 1kifH-3q4nA:
undetectable		 1kifH-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 174
GLY A 109
 None
 1.16A 1kifH-3q4nA:
undetectable		 1kifH-3q4nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 166
GLY A 109
 None
 1.22A 2du8J-3q4nA:
undetectable		 2du8J-3q4nA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 5 TYR A 161
TYR A 171
ILE A 174
GLY A 109
 None
 1.21A 2du8J-3q4nA:
undetectable		 2du8J-3q4nA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		5 / 12 LEU A  30
ASP A  33
VAL A  34
ILE A  79
GLY A  80
 None
 0.93A 3hgiA-3q4nA:
undetectable		 3hgiA-3q4nA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		5 / 12 GLN A 164
LEU A 154
GLY A  98
ALA A 105
SER A 101
 None
 1.06A 3kk6A-3q4nA:
undetectable		 3kk6A-3q4nA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		3 / 3 LYS A 107
LEU A 154
ALA A 110
 None
 0.70A 4iizA-3q4nA:
undetectable		 4iizA-3q4nA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 6 LEU A  44
ILE A  46
LEU A 106
TYR A 157
 None
 0.97A 4w5nA-3q4nA:
undetectable		 4w5nA-3q4nA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 6 ILE A 166
ARG A 144
ILE A 174
GLU A 173
 None
 1.38A 4zzcA-3q4nA:
4.5
4zzcB-3q4nA:
4.4		 4zzcA-3q4nA:
19.44
4zzcB-3q4nA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 6 ILE A 166
ARG A 144
ILE A 174
GLU A 173
 None
 1.39A 4zzcB-3q4nA:
4.4
4zzcC-3q4nA:
4.5		 4zzcB-3q4nA:
19.44
4zzcC-3q4nA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3q4n UNCHARACTERIZED
PROTEIN MJ0754
(Methanocaldococc
us
jannaschii) 		4 / 4 GLN A  55
THR A  56
GLU A  28
LEU A  65
 None
 1.44A 5m66A-3q4nA:
undetectable		 5m66A-3q4nA:
19.96