SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q54'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		4 / 6 PHE A  42
ALA A 358
ILE A 390
PRO A  44
 None
 1.17A 1oniH-3q54A:
undetectable
1oniI-3q54A:
undetectable		 1oniH-3q54A:
18.03
1oniI-3q54A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		4 / 8 LEU A 272
ALA A 218
ILE A 227
GLY A 205
 None
 0.82A 1sv9A-3q54A:
undetectable		 1sv9A-3q54A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		4 / 5 TRP A 183
ALA A 206
LEU A 161
ALA A 207
 None
 1.31A 2jstA-3q54A:
undetectable
2jstB-3q54A:
undetectable		 2jstA-3q54A:
11.21
2jstB-3q54A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 11 GLY A 344
ASP A 363
ALA A 382
GLY A 366
VAL A 362
 None
 1.27A 4c5lA-3q54A:
undetectable		 4c5lA-3q54A:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 9 GLY A 344
ASP A 363
ALA A 382
GLY A 366
VAL A 362
 None
 1.29A 4c5lB-3q54A:
undetectable		 4c5lB-3q54A:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 10 GLY A 344
ASP A 363
ALA A 382
GLY A 366
VAL A 362
 None
 1.25A 4c5lC-3q54A:
undetectable		 4c5lC-3q54A:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 10 GLY A 344
ASP A 363
ALA A 382
GLY A 366
VAL A 362
 None
 1.27A 4c5lD-3q54A:
undetectable		 4c5lD-3q54A:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 10 GLY A 344
ASP A 363
ALA A 382
GLY A 366
VAL A 362
 None
 1.31A 4c5nD-3q54A:
undetectable		 4c5nD-3q54A:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		3 / 3 ASP A 300
ARG A 304
ASP A 288
 None
 0.87A 4fp9C-3q54A:
undetectable		 4fp9C-3q54A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		3 / 3 ASP A 300
ARG A 304
ASP A 288
 None
 0.87A 4fp9F-3q54A:
undetectable		 4fp9F-3q54A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 12 LEU A 110
GLY A 125
VAL A 141
LEU A  97
VAL A  95
 None
 0.95A 4gc9A-3q54A:
undetectable		 4gc9A-3q54A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		3 / 3 LYS A  82
LEU A  84
ALA A  74
 None
 0.58A 4iizA-3q54A:
undetectable		 4iizA-3q54A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA207_0
(OXIDOREDUCTASE)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		4 / 4 GLU A 343
GLY A 344
HIS A 347
ARG A 325
 None
 0.77A 4r82A-3q54A:
undetectable
4r82B-3q54A:
undetectable		 4r82A-3q54A:
21.64
4r82B-3q54A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 10 ASP A 384
VAL A 362
PHE A 367
SER A 365
SER A 364
 None
 1.09A 4xp1A-3q54A:
undetectable		 4xp1A-3q54A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		4 / 8 ALA A 133
VAL A 131
VAL A 157
HIS A 121
 None
 0.64A 5ecnD-3q54A:
undetectable		 5ecnD-3q54A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 8 SER A 365
THR A 386
GLY A 385
ALA A 382
GLY A  55
 None
 1.14A 5vw9A-3q54A:
undetectable		 5vw9A-3q54A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGG_A_SAMA504_0
(RADICAL SAM DOMAIN
PROTEIN)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 12 PHE A 289
PRO A 330
ARG A 154
THR A 201
VAL A 209
 None
 1.50A 5wggA-3q54A:
undetectable		 5wggA-3q54A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		5 / 12 LEU A 171
VAL A 185
GLY A 224
TRP A 228
VAL A 216
 None
 1.24A 6a94A-3q54A:
undetectable		 6a94A-3q54A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 3q54 OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL
(Escherichia
coli) 		4 / 6 LEU A 111
ALA A 109
LEU A 134
SER A  96
 None
 0.97A 6f88B-3q54A:
undetectable		 6f88B-3q54A:
15.05