SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q5e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 6 PHE A 293
PHE A  82
LEU A 286
VAL A 100
 None
GDP  A3850 (-4.2A)
None
None
 0.78A 1hk1A-3q5eA:
4.0		 1hk1A-3q5eA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 6 TYR A 328
GLY A 410
PHE A 413
SER A 414
 None
 1.10A 2a3cA-3q5eA:
undetectable		 2a3cA-3q5eA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 6 TYR A 328
GLY A 410
PHE A 413
SER A 414
 None
 1.06A 2a3cB-3q5eA:
undetectable		 2a3cB-3q5eA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 5 LEU A 304
ILE A 213
LEU A 212
SER A 211
 None
 0.96A 2byoA-3q5eA:
undetectable		 2byoA-3q5eA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 3q5e ATLASTIN-1
(Homo
sapiens) 		3 / 3 PHE A 235
VAL A 216
TRP A 219
 None
 0.80A 2cc8A-3q5eA:
undetectable		 2cc8A-3q5eA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 3q5e ATLASTIN-1
(Homo
sapiens) 		3 / 3 PHE A 235
VAL A 216
TRP A 219
 None
 0.79A 2ccbA-3q5eA:
undetectable		 2ccbA-3q5eA:
7.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3q5e ATLASTIN-1
(Homo
sapiens) 		5 / 12 ASP A 186
VAL A 182
ALA A 233
CYH A 266
VAL A 216
 None
 1.45A 2g70B-3q5eA:
undetectable		 2g70B-3q5eA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 3q5e ATLASTIN-1
(Homo
sapiens) 		3 / 3 PHE A 235
VAL A 216
TRP A 219
 None
 0.79A 2vx9A-3q5eA:
undetectable		 2vx9A-3q5eA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 3q5e ATLASTIN-1
(Homo
sapiens) 		3 / 3 PRO A 208
GLU A 195
TYR A 196
 None
 0.76A 2zmbA-3q5eA:
undetectable		 2zmbA-3q5eA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 3q5e ATLASTIN-1
(Homo
sapiens) 		3 / 3 TYR A 196
TYR A 336
ILE A 335
 None
 0.74A 3eteA-3q5eA:
undetectable
3eteB-3q5eA:
undetectable		 3eteA-3q5eA:
23.21
3eteB-3q5eA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 3q5e ATLASTIN-1
(Homo
sapiens) 		5 / 12 PHE A 413
GLY A 409
ARG A 416
GLU A 353
ALA A 331
 None
 1.28A 3jzjA-3q5eA:
undetectable		 3jzjA-3q5eA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 7 GLY A  33
TYR A  92
GLY A 109
THR A 108
 None
 0.71A 3tajA-3q5eA:
undetectable		 3tajA-3q5eA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 3q5e ATLASTIN-1
(Homo
sapiens) 		3 / 3 LEU A 394
GLU A 396
SER A 398
 None
 0.73A 4ccqA-3q5eA:
undetectable		 4ccqA-3q5eA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 4 LEU A 192
LEU A 166
GLN A 154
GLU A 340
 None
 1.02A 4i41A-3q5eA:
undetectable		 4i41A-3q5eA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 6 ILE A 125
SER A 171
PHE A 329
LEU A 325
 None
 0.69A 4m51A-3q5eA:
undetectable		 4m51A-3q5eA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 8 ASN A 177
MET A  87
LEU A 297
ILE A 213
 None
 1.03A 4ok1A-3q5eA:
undetectable		 4ok1A-3q5eA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 3q5e ATLASTIN-1
(Homo
sapiens) 		3 / 3 TRP A 303
ILE A 173
SER A 211
 None
 1.03A 5gqbA-3q5eA:
undetectable		 5gqbA-3q5eA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 8 GLN A 337
ALA A 350
GLN A 349
SER A 346
 None
 1.05A 5km8A-3q5eA:
undetectable
5km8B-3q5eA:
undetectable		 5km8A-3q5eA:
14.29
5km8B-3q5eA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 6 PRO A 380
ILE A 374
GLY A 376
GLU A 373
 None
 1.14A 6gqiA-3q5eA:
undetectable		 6gqiA-3q5eA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_1
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 3q5e ATLASTIN-1
(Homo
sapiens) 		4 / 5 GLN A 431
ASP A 426
ASN A 436
TYR A 367
 None
 1.50A 6iftA-3q5eA:
undetectable		 6iftA-3q5eA:
20.89