SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q5m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3q5m UPF0169 LIPOPROTEIN
YFIO
(Escherichia
coli) 		5 / 12 LEU A 128
GLY A  91
ASP A 124
ALA A 121
ALA A 118
 None
 1.17A 2br4B-3q5mA:
undetectable		 2br4B-3q5mA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3q5m UPF0169 LIPOPROTEIN
YFIO
(Escherichia
coli) 		4 / 5 ILE A  13
PRO A  10
TYR A  45
TYR A  14
 IOD  A 226 (-4.3A)
IOD  A 229 ( 4.8A)
None
None
 1.31A 3d9lA-3q5mA:
3.4
3d9lY-3q5mA:
undetectable		 3d9lA-3q5mA:
18.42
3d9lY-3q5mA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 3q5m UPF0169 LIPOPROTEIN
YFIO
(Escherichia
coli) 		4 / 5 PRO A   9
ILE A  13
TYR A  45
TYR A  14
 None
IOD  A 226 (-4.3A)
None
None
 1.14A 3d9lA-3q5mA:
3.4
3d9lY-3q5mA:
undetectable		 3d9lA-3q5mA:
18.42
3d9lY-3q5mA:
4.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3q5m UPF0169 LIPOPROTEIN
YFIO
(Escherichia
coli) 		4 / 4 ILE A 216
SER A 220
ASP A 191
ASP A 150
 None
 1.48A 4krhB-3q5mA:
undetectable		 4krhB-3q5mA:
20.44