SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q5t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 3q5t TCR N30 BETA
(Mus
musculus) 		5 / 8 HIS A  30
SER A  95
VAL A 103
GLY A  98
GLY A 100
 None
 1.29A 1aq7A-3q5tA:
undetectable		 1aq7A-3q5tA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3q5t TCR N30 BETA
(Mus
musculus) 		3 / 3 THR A 121
PRO A 123
PRO A 226
 None
 0.90A 2d55C-3q5tA:
undetectable		 2d55C-3q5tA:
7.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3q5t TCR N30 BETA
(Mus
musculus) 		4 / 8 GLY A 212
VAL A 120
PRO A 152
ARG A 110
 None
 1.05A 3bgdB-3q5tA:
undetectable		 3bgdB-3q5tA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 3q5t TCR N30 BETA
(Mus
musculus) 		3 / 3 PRO A 130
PHE A 196
LYS A 140
 None
 1.07A 3bjwG-3q5tA:
undetectable		 3bjwG-3q5tA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3q5t TCR N30 BETA
(Mus
musculus) 		4 / 6 GLY A  73
GLU A  53
ASP A  25
ASP A  52
 None
 1.00A 4uckB-3q5tA:
undetectable		 4uckB-3q5tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3q5t TCR N30 BETA
(Mus
musculus) 		4 / 7 SER A 223
ASP A 217
GLY A 212
THR A 112
 None
 0.98A 5btaA-3q5tA:
undetectable
5btaC-3q5tA:
undetectable
5btaD-3q5tA:
undetectable		 5btaA-3q5tA:
18.97
5btaC-3q5tA:
18.97
5btaD-3q5tA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 3q5t TCR N30 BETA
(Mus
musculus) 		4 / 7 SER A 223
ASP A 217
GLY A 212
THR A 112
 None
 1.00A 5btfA-3q5tA:
undetectable
5btfC-3q5tA:
undetectable
5btfD-3q5tA:
undetectable		 5btfA-3q5tA:
18.97
5btfC-3q5tA:
18.97
5btfD-3q5tA:
20.92