SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q5w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 3q5w PROTEIN CUT8
(Schizosaccharomy
ces
pombe) 		6 / 12 LEU A 169
THR A 170
LEU A 177
LEU A 126
HIS A 197
LEU A 194
 None
 1.43A 2ouzA-3q5wA:
undetectable		 2ouzA-3q5wA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3q5w PROTEIN CUT8
(Schizosaccharomy
ces
pombe) 		3 / 3 LEU A 212
TYR A 211
GLN A 214
 None
 0.72A 2wekA-3q5wA:
undetectable		 2wekA-3q5wA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 3q5w PROTEIN CUT8
(Schizosaccharomy
ces
pombe) 		4 / 6 VAL A 176
VAL A 175
PHE A 139
ARG A 178
 None
 1.21A 3bjwF-3q5wA:
1.1		 3bjwF-3q5wA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 3q5w PROTEIN CUT8
(Schizosaccharomy
ces
pombe) 		5 / 9 GLY A  95
PRO A  93
PRO A 151
GLY A 100
TYR A 102
 None
 1.31A 4fimA-3q5wA:
undetectable		 4fimA-3q5wA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 3q5w PROTEIN CUT8
(Schizosaccharomy
ces
pombe) 		3 / 3 TRP A 173
GLN A 164
THR A 170
 None
 1.01A 4m2xA-3q5wA:
undetectable		 4m2xA-3q5wA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 3q5w PROTEIN CUT8
(Schizosaccharomy
ces
pombe) 		4 / 5 GLN A 179
THR A 144
HIS A 197
LEU A 194
 None
 1.38A 6gbnA-3q5wA:
undetectable		 6gbnA-3q5wA:
21.75