SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q62'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		5 / 11 ARG A   5
VAL A   2
ILE A  40
LEU A  13
ASP A  12
 None
 1.09A 2q6hA-3q62A:
undetectable		 2q6hA-3q62A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		5 / 11 ARG A   5
VAL A   2
ILE A  40
PHE A  93
ASP A  12
 None
 1.13A 2q6hA-3q62A:
undetectable		 2q6hA-3q62A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		5 / 11 ARG A   5
VAL A   2
ILE A  40
LEU A  13
ASP A  12
 None
 1.10A 2q72A-3q62A:
undetectable		 2q72A-3q62A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		6 / 12 ARG A   5
VAL A   2
ILE A  40
PHE A  93
LEU A  13
ASP A  12
 None
 1.11A 2qb4A-3q62A:
undetectable		 2qb4A-3q62A:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QJU_A_DSMA801_1
(TRANSPORTER)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		5 / 11 ARG A   5
ILE A  40
PHE A  93
LEU A  13
ASP A  12
 None
 0.97A 2qjuA-3q62A:
undetectable		 2qjuA-3q62A:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		4 / 8 THR A 126
TYR A 156
ARG A 128
MET A  87
 None
 1.47A 3wipC-3q62A:
undetectable
3wipD-3q62A:
undetectable		 3wipC-3q62A:
18.42
3wipD-3q62A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		4 / 5 LEU A  29
ALA A  86
VAL A  55
ILE A 129
 None
 0.91A 4xe3B-3q62A:
undetectable		 4xe3B-3q62A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		4 / 6 LYS A  -2
GLU A 101
GLY A  26
GLY A  23
 None
 0.93A 5a06D-3q62A:
undetectable		 5a06D-3q62A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		3 / 3 LEU A  65
ILE A  61
TYR A 127
 None
 0.60A 5uunB-3q62A:
undetectable		 5uunB-3q62A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_2
(PROTEASE)		 3q62 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE
(Yersinia
pestis) 		3 / 3 LEU A 107
ASP A 145
ILE A 129
 MES  A 173 (-4.8A)
None
None
 0.65A 6dh0B-3q62A:
undetectable		 6dh0B-3q62A:
21.39