SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q6d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1871_0
(FPRA)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 7 PHE A 213
ALA A 143
PHE A 147
SER A 346
 None
 0.96A 1lqtA-3q6dA:
undetectable		 1lqtA-3q6dA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 7 PHE A 213
ALA A 143
PHE A 147
SER A 346
 None
 0.96A 1lquA-3q6dA:
undetectable		 1lquA-3q6dA:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 12 ILE A 228
GLY A 188
ILE A 203
VAL A 327
PRO A 233
 None
 1.13A 1sg9A-3q6dA:
undetectable		 1sg9A-3q6dA:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 8 THR A 305
VAL A 313
GLY A 288
ILE A 127
 None
 0.81A 2a1mB-3q6dA:
undetectable		 2a1mB-3q6dA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 7 THR A 129
ALA A  31
TYR A  66
ASN A  32
 None
 1.17A 2hzqA-3q6dA:
undetectable		 2hzqA-3q6dA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 9 LYS A 236
GLU A 239
ILE A 240
ILE A 321
ILE A 319
 None
 1.16A 2j9dA-3q6dA:
0.9
2j9dB-3q6dA:
0.0
2j9dC-3q6dA:
0.0		 2j9dA-3q6dA:
20.07
2j9dB-3q6dA:
20.07
2j9dC-3q6dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 10 ILE A 319
LYS A 236
GLU A 239
ILE A 240
ILE A 321
 None
 1.22A 2j9dD-3q6dA:
undetectable
2j9dE-3q6dA:
undetectable
2j9dF-3q6dA:
0.9		 2j9dD-3q6dA:
20.07
2j9dE-3q6dA:
16.85
2j9dF-3q6dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_E_ACTE1116_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 10 LYS A 236
GLU A 239
ILE A 240
ILE A 321
ILE A 319
 None
 1.19A 2j9dD-3q6dA:
undetectable
2j9dE-3q6dA:
undetectable
2j9dF-3q6dA:
0.9		 2j9dD-3q6dA:
20.07
2j9dE-3q6dA:
16.85
2j9dF-3q6dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 9 ILE A 321
ILE A 319
LYS A 236
GLU A 239
ILE A 240
 None
 1.20A 2j9dG-3q6dA:
1.1
2j9dH-3q6dA:
undetectable
2j9dI-3q6dA:
0.4		 2j9dG-3q6dA:
20.07
2j9dH-3q6dA:
20.07
2j9dI-3q6dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_H_ACTH1113_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 9 LYS A 236
GLU A 239
ILE A 240
ILE A 321
ILE A 319
 None
 1.15A 2j9dG-3q6dA:
1.1
2j9dH-3q6dA:
undetectable
2j9dI-3q6dA:
0.4		 2j9dG-3q6dA:
20.07
2j9dH-3q6dA:
20.07
2j9dI-3q6dA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_C_ACTC36_0
(GCN4 LEUCINE ZIPPER)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 10 ALA A 176
ALA A 139
ALA A 215
SER A 180
TYR A 216
 None
 1.09A 2r2vC-3q6dA:
undetectable
2r2vF-3q6dA:
undetectable
2r2vG-3q6dA:
undetectable		 2r2vC-3q6dA:
7.08
2r2vF-3q6dA:
7.08
2r2vG-3q6dA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 11 PHE A  11
ILE A  76
ALA A 109
GLU A  94
LEU A  91
 None
 1.39A 2v0mA-3q6dA:
1.5		 2v0mA-3q6dA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 9 ILE A  76
ALA A 109
GLU A  94
GLY A  18
LEU A  91
 None
 1.28A 2v0mB-3q6dA:
undetectable		 2v0mB-3q6dA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 12 ILE A 319
TYR A 280
GLY A 325
LEU A 237
ILE A 324
 None
 1.22A 2y7kD-3q6dA:
undetectable		 2y7kD-3q6dA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA601_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 7 GLY A 214
SER A 222
ALA A 176
ALA A 139
ILE A 183
 None
 1.24A 3a2qA-3q6dA:
undetectable		 3a2qA-3q6dA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 7 SER A 102
HIS A 106
THR A  22
LEU A  20
 None
 1.23A 3arrA-3q6dA:
undetectable		 3arrA-3q6dA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_2
(DIHYDROFOLATE
REDUCTASE)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 4 ILE A 333
ARG A 269
ILE A 255
THR A 344
 None
 1.09A 3ia4C-3q6dA:
undetectable		 3ia4C-3q6dA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 8 THR A 285
VAL A 313
VAL A 315
GLN A 248
 None
 0.87A 4em2A-3q6dA:
undetectable		 4em2A-3q6dA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_B_MOAB502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 8 SER A 179
SER A 178
GLY A 175
GLY A 219
 None
 0.89A 4fo4B-3q6dA:
undetectable		 4fo4B-3q6dA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		3 / 3 GLY A 318
GLU A 316
THR A 285
 None
CA  A 502 (-3.7A)
None
 0.49A 4kouA-3q6dA:
undetectable		 4kouA-3q6dA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 12 ALA A 312
GLY A 214
GLY A 290
ASP A 331
THR A 344
 None
 1.04A 4mm8A-3q6dA:
undetectable		 4mm8A-3q6dA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 7 ALA A 146
GLY A 175
ALA A 176
SER A 222
 None
 0.87A 4r1zB-3q6dA:
undetectable		 4r1zB-3q6dA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		4 / 7 ALA A 146
ILE A 183
LEU A 211
PHE A 213
 None
 1.14A 4uymB-3q6dA:
undetectable		 4uymB-3q6dA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3q6d PROLINE DIPEPTIDASE
(Bacillus
anthracis) 		5 / 12 ILE A 154
PHE A 153
ILE A 150
ALA A 198
VAL A 158
 None
 1.15A 5km9B-3q6dA:
undetectable		 5km9B-3q6dA:
20.61