SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q6g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 3q6g LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		4 / 8 VAL L 106
ARG L  61
ALA L  19
GLU L  83
 None
 0.83A 1dmiA-3q6gL:
undetectable
1dmiB-3q6gL:
undetectable		 1dmiA-3q6gL:
20.86
1dmiB-3q6gL:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I9J_H_TESH1010_1
(RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT HEAVY
CHAIN
RECOMBINANT
MONOCLONAL
ANTI-TESTOSTERONE
FAB FRAGMENT LIGHT
CHAIN)		 3q6g HEAVY CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		5 / 11 SER H  35
TRP H  47
TYR H 100
GLY H 100
LEU H 100
 None
 0.86A 1i9jH-3q6gH:
25.8
1i9jL-3q6gH:
14.5		 1i9jH-3q6gH:
55.32
1i9jL-3q6gH:
27.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3q6g LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		4 / 6 GLY L  24
GLN L   6
VAL L  33
ALA L  71
 None
 0.77A 1p6kA-3q6gL:
undetectable		 1p6kA-3q6gL:
16.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 3q6g HEAVY CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		5 / 12 SER H  35
TRP H  47
TYR H 100
GLY H 100
LEU H 100
 None
 0.80A 1vpoH-3q6gH:
20.0
1vpoL-3q6gH:
14.4		 1vpoH-3q6gH:
54.62
1vpoL-3q6gH:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 3q6g LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		5 / 11 LEU L  73
VAL L  78
GLY L  77
ALA L  19
LEU L 104
 None
 1.13A 2bxgA-3q6gL:
undetectable		 2bxgA-3q6gL:
16.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3q6g HEAVY CHAIN OF FAB
OF RHESUS MAB 2.5B
LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta;
Macaca
mulatta) 		4 / 7 TYR H  91
TYR L  36
PRO L  44
TYR L  87
 None
 0.73A 2oldA-3q6gH:
19.3
2oldB-3q6gH:
14.2		 2oldA-3q6gH:
31.56
2oldB-3q6gH:
31.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3q6g HEAVY CHAIN OF FAB
OF RHESUS MAB 2.5B
LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta;
Macaca
mulatta) 		4 / 7 TYR L  36
PRO L  44
TYR L  87
TYR H  91
 None
 0.69A 2oldA-3q6gL:
19.5
2oldB-3q6gL:
23.8		 2oldA-3q6gL:
71.83
2oldB-3q6gL:
71.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3q6g HEAVY CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		4 / 5 LEU H  80
ILE H  95
TRP H 103
TYR H  59
 None
 1.31A 2zlcA-3q6gH:
undetectable		 2zlcA-3q6gH:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3q6g LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		4 / 4 GLN L  17
PRO L  15
VAL L  78
GLU L  79
 None
 1.14A 3huoA-3q6gL:
undetectable		 3huoA-3q6gL:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBR_A_ASDA129_1
(STEROID
DELTA-ISOMERASE)		 3q6g HEAVY CHAIN OF FAB
OF RHESUS MAB 2.5B
LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		5 / 12 PHE H 166
VAL L 195
VAL L 144
PRO L 113
PHE L 139
 None
 1.37A 3nbrA-3q6gH:
0.0		 3nbrA-3q6gH:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3q6g LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		4 / 8 THR L  74
TYR L  86
TRP L  35
ARG L  20
 None
 1.19A 3wipB-3q6gL:
undetectable
3wipC-3q6gL:
undetectable		 3wipB-3q6gL:
20.42
3wipC-3q6gL:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 3q6g HEAVY CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		5 / 10 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.48A 4ldoA-3q6gH:
undetectable		 4ldoA-3q6gH:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4E_D_EDPD402_1
(PROTON-GATED ION
CHANNEL)		 3q6g LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		4 / 8 THR L  74
SER L  63
THR L  72
SER L  65
 None
 1.01A 5l4eA-3q6gL:
undetectable
5l4eB-3q6gL:
undetectable
5l4eC-3q6gL:
undetectable
5l4eD-3q6gL:
undetectable
5l4eE-3q6gL:
undetectable		 5l4eA-3q6gL:
20.26
5l4eB-3q6gL:
20.26
5l4eC-3q6gL:
20.26
5l4eD-3q6gL:
20.26
5l4eE-3q6gL:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 3q6g HEAVY CHAIN OF FAB
OF RHESUS MAB 2.5B
(Macaca
mulatta) 		5 / 12 VAL H 163
VAL H 182
SER H 180
ASN H 197
ASN H 155
 None
 1.44A 6h7mB-3q6gH:
undetectable		 6h7mB-3q6gH:
16.98