SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q6s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 3q6s CHROMOBOX PROTEIN
HOMOLOG 1
(Homo
sapiens) 		5 / 10 ALA A 144
LEU A 146
VAL A 147
LEU A 132
ILE A 122
 None
 1.19A 3jw3A-3q6sA:
undetectable		 3jw3A-3q6sA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3q6s CHROMOBOX PROTEIN
HOMOLOG 1
(Homo
sapiens) 		3 / 3 LEU A 168
ARG A 167
MET A 136
 None
 0.80A 4m11C-3q6sA:
undetectable		 4m11C-3q6sA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)		 3q6s CHROMOBOX PROTEIN
HOMOLOG 1
(Homo
sapiens) 		4 / 7 ALA A 149
GLY A 124
ALA A 125
SER A 129
 None
 0.81A 4r1zB-3q6sA:
undetectable		 4r1zB-3q6sA:
12.69