SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q71'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H4J_A_NCAA1002_0 (NAD-DEPENDENT DEACETYLASE)	3q71	POLY [ADP-RIBOSE] POLYMERASE 14 (Homo sapiens)	4 / 5	ALA A1131 ASN A1178 ILE A1179 ASP A1175	AR6 A 800 (-4.2A) AR6 A 800 (-4.2A) None AR6 A 800 (-3.4A)	1.00A	2h4jA-3q71A: undetectable	2h4jA-3q71A: 22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_S_TFPS201_1 (PROTEIN S100-A4)	3q71	POLY [ADP-RIBOSE] POLYMERASE 14 (Homo sapiens)	4 / 7	PHE A1144 GLY A1074 PHE A1169 PHE A1182	None	1.13A	3ko0K-3q71A: undetectable 3ko0S-3q71A: undetectable	3ko0K-3q71A: 16.74 3ko0S-3q71A: 16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X61_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	3q71	POLY [ADP-RIBOSE] POLYMERASE 14 (Homo sapiens)	5 / 12	GLY A1133 GLY A1135 PRO A1045 LEU A1046 MET A1108	AR6 A 800 (-3.4A) AR6 A 800 (-3.1A) AR6 A 800 (-3.3A) AR6 A 800 (-3.6A) None	1.21A	4x61A-3q71A: 2.9	4x61A-3q71A: 16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F5U_A_CQNA610_1 (ENVELOPE GLYCOPROTEIN,ENVELOP E GLYCOPROTEIN,GP1 ENVELOPE GLYCOPROTEIN)	3q71	POLY [ADP-RIBOSE] POLYMERASE 14 (Homo sapiens)	5 / 10	VAL A1031 ALA A1128 LEU A1084 LEU A1046 LEU A1050	None None None AR6 A 800 (-3.6A) None	0.99A	6f5uA-3q71A: undetectable 6f5uB-3q71A: undetectable	6f5uA-3q71A: 19.15 6f5uB-3q71A: 15.53

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2H4J_A_NCAA1002_0","NAD-DEPENDENT DEACETYLASE","3q71","POLY [ADP-RIBOSE] POLYMERASE 14","Homo sapiens",4,"ALA A1131;ASN A1178;ILE A1179;ASP A1175","AR6 A 800 (-4.2A);AR6 A 800 (-4.2A);None;AR6 A 800 (-3.4A)","1.00A","2h4jA-3q71A:undetectable","2h4jA-3q71A:22.26"],["3KO0_S_TFPS201_1","PROTEIN S100-A4;PROTEIN S100-A4","3q71","POLY [ADP-RIBOSE] POLYMERASE 14","Homo sapiens",4,"PHE A1144;GLY A1074;PHE A1169;PHE A1182","None","1.13A","3ko0K-3q71A:undetectable;3ko0S-3q71A:undetectable","3ko0K-3q71A:16.74;3ko0S-3q71A:16.74"],["4X61_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","3q71","POLY [ADP-RIBOSE] POLYMERASE 14","Homo sapiens",5,"GLY A1133;GLY A1135;PRO A1045;LEU A1046;MET A1108","AR6 A 800 (-3.4A);AR6 A 800 (-3.1A);AR6 A 800 (-3.3A);AR6 A 800 (-3.6A);None","1.21A","4x61A-3q71A:2.9","4x61A-3q71A:16.41"],["6F5U_A_CQNA610_1","ENVELOPE GLYCOPROTEIN,ENVELOPE GLYCOPROTEIN,GP1;ENVELOPE GLYCOPROTEIN","3q71","POLY [ADP-RIBOSE] POLYMERASE 14","Homo sapiens",5,"VAL A1031;ALA A1128;LEU A1084;LEU A1046;LEU A1050","None;None;None;AR6 A 800 (-3.6A);None","0.99A","6f5uA-3q71A:undetectable;6f5uB-3q71A:undetectable","6f5uA-3q71A:19.15;6f5uB-3q71A:15.53"]]