SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA502_1
(YKOF)		 3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Coxiella
burnetii) 		4 / 6 ALA A 102
LEU A 104
ILE A  65
CYH A 115
 None
 0.98A 1sbrA-3q7hA:
undetectable
1sbrB-3q7hA:
undetectable		 1sbrA-3q7hA:
22.07
1sbrB-3q7hA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Coxiella
burnetii) 		5 / 12 SER A  99
ILE A 154
LEU A 151
THR A  91
VAL A  72
 None
 1.21A 3dcjA-3q7hA:
undetectable
3dcjB-3q7hA:
undetectable		 3dcjA-3q7hA:
23.01
3dcjB-3q7hA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Coxiella
burnetii) 		5 / 12 LEU A 155
GLY A 101
ALA A 106
GLY A 107
LEU A  63
 None
 0.94A 3ku1C-3q7hA:
undetectable		 3ku1C-3q7hA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Coxiella
burnetii) 		5 / 12 LEU A 155
GLY A 101
ALA A 106
GLY A 107
LEU A  63
 None
 0.92A 3ku1G-3q7hA:
undetectable		 3ku1G-3q7hA:
25.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Coxiella
burnetii) 		4 / 5 SER A  99
ALA A 102
HIS A 124
LEU A 151
 None
 1.43A 5dzkb-3q7hA:
26.8
5dzkp-3q7hA:
undetectable		 5dzkb-3q7hA:
47.12
5dzkp-3q7hA:
1.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Coxiella
burnetii) 		4 / 5 SER A  99
ALA A 102
HIS A 124
LEU A 151
 None
 1.45A 5dzkc-3q7hA:
26.9
5dzkq-3q7hA:
undetectable		 5dzkc-3q7hA:
47.12
5dzkq-3q7hA:
1.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Coxiella
burnetii) 		4 / 5 SER A  99
ALA A 102
HIS A 124
LEU A 151
 None
 1.44A 5dzkf-3q7hA:
27.0
5dzkt-3q7hA:
undetectable		 5dzkf-3q7hA:
47.12
5dzkt-3q7hA:
1.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Coxiella
burnetii) 		3 / 3 HIS A  40
ASN A  43
ALA A  47
 None
 0.53A 5n4tB-3q7hA:
undetectable		 5n4tB-3q7hA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3q7h ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT
(Coxiella
burnetii) 		4 / 9 HIS A 158
ILE A  65
ILE A  94
LEU A 116
 None
 0.78A 5vkqB-3q7hA:
undetectable
5vkqC-3q7hA:
undetectable		 5vkqB-3q7hA:
8.71
5vkqC-3q7hA:
8.71