SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 389
LYS A 392
SER A 437
ASN A 439
LYS A 526
GLY A 528
 BOU  A 584 (-1.4A)
BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
 0.39A 1ghmA-3q7zA:
17.8		 1ghmA-3q7zA:
26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		3 / 4 LYS A 392
ALA A 396
MET A 434
 BOU  A 584 ( 3.9A)
None
None
 1.05A 1hk3A-3q7zA:
undetectable		 1hk3A-3q7zA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 389
LYS A 392
SER A 437
ASN A 439
LYS A 526
GLY A 528
 BOU  A 584 (-1.4A)
BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
 0.43A 1i2wA-3q7zA:
18.3		 1i2wA-3q7zA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 8 TYR A 471
THR A 456
TYR A 453
LEU A 461
 None
 1.44A 1uw6A-3q7zA:
undetectable
1uw6B-3q7zA:
undetectable		 1uw6A-3q7zA:
19.44
1uw6B-3q7zA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 8 TYR A 471
THR A 456
TYR A 453
LEU A 461
 None
 1.47A 1uw6D-3q7zA:
undetectable
1uw6E-3q7zA:
undetectable		 1uw6D-3q7zA:
19.44
1uw6E-3q7zA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 8 TYR A 471
THR A 456
TYR A 453
LEU A 461
 None
 1.46A 1uw6G-3q7zA:
undetectable
1uw6H-3q7zA:
undetectable		 1uw6G-3q7zA:
19.44
1uw6H-3q7zA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 8 TYR A 471
THR A 456
TYR A 453
LEU A 461
 None
 1.45A 1uw6P-3q7zA:
undetectable
1uw6Q-3q7zA:
undetectable		 1uw6P-3q7zA:
19.44
1uw6Q-3q7zA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 8 LEU A 461
TYR A 471
THR A 456
TYR A 453
 None
 1.46A 1uw6P-3q7zA:
undetectable
1uw6T-3q7zA:
undetectable		 1uw6P-3q7zA:
19.44
1uw6T-3q7zA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
LYS A 392
SER A 437
ASN A 439
LYS A 526
GLY A 528
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.46A 1ymxA-3q7zA:
18.2		 1ymxA-3q7zA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
LYS A 392
SER A 437
ASN A 439
LYS A 526
GLY A 528
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.42A 1ymxB-3q7zA:
18.2		 1ymxB-3q7zA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 8 GLY A 528
ILE A 531
ALA A 568
HIS A 557
 BOU  A 584 (-3.7A)
BOU  A 584 (-3.8A)
None
None
 0.92A 2x0pA-3q7zA:
undetectable		 2x0pA-3q7zA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 LYS A 392
SER A 437
ASN A 439
LYS A 526
GLY A 528
GLY A 530
 BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.43A 3hlwA-3q7zA:
18.2		 3hlwA-3q7zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
GLY A 530
 BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.30A 3hlwB-3q7zA:
18.2		 3hlwB-3q7zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 LYS A 392
ASN A 439
LYS A 526
THR A 527
GLY A 528
GLY A 530
 BOU  A 584 ( 3.9A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.40A 3huoA-3q7zA:
18.1		 3huoA-3q7zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		5 / 12 LYS A 392
ASN A 439
LYS A 526
GLY A 528
GLY A 530
 BOU  A 584 ( 3.9A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.43A 3huoB-3q7zA:
18.1		 3huoB-3q7zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 8 ASN A 388
THR A 390
HIS A 557
ASN A 537
 BOU  A 584 (-4.5A)
None
None
None
 1.07A 3kp2A-3q7zA:
undetectable
3kp2B-3q7zA:
undetectable		 3kp2A-3q7zA:
18.90
3kp2B-3q7zA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		5 / 12 ASN A 484
VAL A 364
TYR A 366
TYR A 553
PHE A 491
 None
 1.38A 3megA-3q7zA:
undetectable		 3megA-3q7zA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.56A 3ny4A-3q7zA:
17.7		 3ny4A-3q7zA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 LYS A 392
SER A 437
ASN A 439
LYS A 526
GLY A 528
GLY A 530
 BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.34A 3q07A-3q7zA:
18.0		 3q07A-3q7zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 LYS A 392
SER A 437
ASN A 439
LYS A 526
GLY A 528
GLY A 530
 BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.53A 3q07B-3q7zA:
18.0		 3q07B-3q7zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 389
SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
 0.34A 3sh8A-3q7zA:
18.5		 3sh8A-3q7zA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 389
LYS A 392
SER A 437
ASN A 439
LYS A 526
GLY A 528
 BOU  A 584 (-1.4A)
BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
 0.41A 3sh8B-3q7zA:
18.8		 3sh8B-3q7zA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 LYS A 392
SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
THR A 529
 BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
 0.60A 4euzA-3q7zA:
17.9		 4euzA-3q7zA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		5 / 10 SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
 BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
 0.53A 4fh2A-3q7zA:
17.0		 4fh2A-3q7zA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 8 ILE A 375
ILE A 489
MET A 368
LYS A 551
 None
 0.80A 4hdlA-3q7zA:
undetectable		 4hdlA-3q7zA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 389
SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
 0.29A 4n9kA-3q7zA:
18.5		 4n9kA-3q7zA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 389
SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
 0.29A 4n9kB-3q7zA:
18.6		 4n9kB-3q7zA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 5 ASN A 345
TYR A 347
ILE A 375
ARG A 382
 None
 1.42A 4o0oA-3q7zA:
undetectable		 4o0oA-3q7zA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		3 / 3 MET A 368
MET A 579
TYR A 544
 None
 1.30A 4p6xI-3q7zA:
undetectable		 4p6xI-3q7zA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
GLY A 530
 BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.64A 4pm5A-3q7zA:
18.0		 4pm5A-3q7zA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 LYS A 392
SER A 437
ASN A 439
LYS A 526
GLY A 528
GLY A 530
 BOU  A 584 ( 3.9A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.72A 4pm7A-3q7zA:
18.1		 4pm7A-3q7zA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
GLY A 530
 BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.66A 4pm9A-3q7zA:
18.2		 4pm9A-3q7zA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_B_SVRB207_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 7 LYS A 466
TYR A 394
LEU A 395
PHE A 442
 None
 1.19A 4yv5B-3q7zA:
undetectable		 4yv5B-3q7zA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		5 / 12 SER A 389
SER A 437
ASN A 439
LYS A 526
GLY A 528
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
 0.31A 5ghyB-3q7zA:
18.6		 5ghyB-3q7zA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 11 SER A 389
SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
 0.30A 5ghzA-3q7zA:
18.6		 5ghzA-3q7zA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 10 SER A 389
SER A 437
ASN A 439
LYS A 526
THR A 527
GLY A 528
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
 0.33A 5ghzB-3q7zA:
18.5		 5ghzB-3q7zA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		4 / 7 TYR A 391
GLN A 487
TRP A 475
TYR A 471
 None
 1.18A 5ov9B-3q7zA:
undetectable		 5ov9B-3q7zA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.50A 6b5yB-3q7zA:
17.9		 6b5yB-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.52A 6b5yD-3q7zA:
17.7		 6b5yD-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.38A 6b68B-3q7zA:
17.8		 6b68B-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		6 / 12 SER A 389
SER A 437
LYS A 526
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.43A 6b68D-3q7zA:
17.7		 6b68D-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.38A 6b69A-3q7zA:
17.8
6b69B-3q7zA:
17.3		 6b69A-3q7zA:
14.22
6b69B-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.35A 6b69D-3q7zA:
17.6		 6b69D-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.41A 6b6aB-3q7zA:
17.7		 6b6aB-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.38A 6b6aD-3q7zA:
17.6		 6b6aD-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.47A 6b6cA-3q7zA:
17.7		 6b6cA-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.57A 6b6dA-3q7zA:
17.6		 6b6dA-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.43A 6b6eA-3q7zA:
17.7		 6b6eA-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		7 / 12 SER A 389
SER A 437
LYS A 526
THR A 527
GLY A 528
THR A 529
GLY A 530
 BOU  A 584 (-1.4A)
BOU  A 584 (-2.8A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.6A)
BOU  A 584 (-3.7A)
BOU  A 584 (-3.6A)
BOU  A 584 ( 3.9A)
 0.55A 6b6fA-3q7zA:
17.5		 6b6fA-3q7zA:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 3q7z BETA-LACTAMASE
REGULATORY PROTEIN
BLAR1
(Staphylococcus
aureus) 		5 / 12 SER A 437
ASN A 439
LYS A 526
GLY A 528
GLY A 530
 BOU  A 584 (-2.8A)
BOU  A 584 (-3.5A)
BOU  A 584 (-3.3A)
BOU  A 584 (-3.7A)
BOU  A 584 ( 3.9A)
 0.30A 6c79A-3q7zA:
18.4		 6c79A-3q7zA:
16.38