SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 PRO B   6
ASN B  85
GLY B  31
ASP B  51
VAL B 106
 SAM  B 300 ( 4.5A)
SAM  B 300 (-3.9A)
SAM  B 300 (-3.5A)
SAM  B 300 (-2.9A)
None
 1.29A 1ffyA-3q87B:
undetectable		 1ffyA-3q87B:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 PRO B   6
GLY B  31
THR B  50
ASN B  85
PRO B  87
 SAM  B 300 ( 4.5A)
SAM  B 300 (-3.5A)
None
SAM  B 300 (-3.9A)
SAM  B 300 (-4.1A)
 0.39A 1nv8A-3q87B:
17.6		 1nv8A-3q87B:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 THR B  10
GLY B  31
THR B  50
ASN B  85
PRO B  87
 SAM  B 300 (-3.2A)
SAM  B 300 (-3.5A)
None
SAM  B 300 (-3.9A)
SAM  B 300 (-4.1A)
 0.89A 1nv8A-3q87B:
17.6		 1nv8A-3q87B:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 THR B  10
GLY B  31
ILE B  37
THR B  50
PRO B  87
 SAM  B 300 (-3.2A)
SAM  B 300 (-3.5A)
None
None
SAM  B 300 (-4.1A)
 0.85A 1nv8B-3q87B:
17.9		 1nv8B-3q87B:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_0
(HEMK PROTEIN)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 PRO B   6
ILE B  37
THR B  50
ASN B  85
PRO B  87
 SAM  B 300 ( 4.5A)
None
None
SAM  B 300 (-3.9A)
SAM  B 300 (-4.1A)
 0.50A 1sg9A-3q87B:
18.2		 1sg9A-3q87B:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		3 / 3 GLY B  31
ASP B  51
ASN B  85
 SAM  B 300 (-3.5A)
SAM  B 300 (-2.9A)
SAM  B 300 (-3.9A)
 0.31A 1vq1A-3q87B:
17.7		 1vq1A-3q87B:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 GLY B  31
LEU B  52
ASP B  69
ASN B  85
PRO B  87
 SAM  B 300 (-3.5A)
SAM  B 300 (-3.9A)
SAM  B 300 (-3.7A)
SAM  B 300 (-3.9A)
SAM  B 300 (-4.1A)
 0.77A 1zq9B-3q87B:
12.8		 1zq9B-3q87B:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		4 / 4 ILE B 107
ASP B  69
LEU B  30
ARG B 135
 None
SAM  B 300 (-3.7A)
None
None
 1.42A 2a7qA-3q87B:
undetectable		 2a7qA-3q87B:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		3 / 3 MET B  24
VAL B  83
GLU B  18
 None
 0.69A 2x9gA-3q87B:
6.1		 2x9gA-3q87B:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 10 TYR B   4
ASP B  51
ASN B  53
ALA B  56
ASP B  69
 SAM  B 300 (-3.5A)
SAM  B 300 (-2.9A)
SAM  B 300 (-4.9A)
None
SAM  B 300 (-3.7A)
 0.68A 3ay0A-3q87B:
14.6		 3ay0A-3q87B:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 ASP B  29
LEU B  30
GLY B  31
VAL B  36
ASP B  51
 SAM  B 300 ( 4.7A)
None
SAM  B 300 (-3.5A)
None
SAM  B 300 (-2.9A)
 0.33A 3cjtC-3q87B:
16.3		 3cjtC-3q87B:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMF_A_SAMA388_0
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 GLY B  31
ASP B  69
ASN B  85
PRO B  87
VAL B 106
 SAM  B 300 (-3.5A)
SAM  B 300 (-3.7A)
SAM  B 300 (-3.9A)
SAM  B 300 (-4.1A)
None
 0.91A 3dmfA-3q87B:
16.2		 3dmfA-3q87B:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3q87 PUTATIVE
UNCHARACTERIZED
PROTEIN ECU08_1170
(Encephalitozoon
cuniculi) 		4 / 6 PHE A  76
PHE A  40
HIS A  43
THR A  46
 None
 1.26A 3lb3A-3q87A:
undetectable		 3lb3A-3q87A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3q87 PUTATIVE
UNCHARACTERIZED
PROTEIN ECU08_1170
(Encephalitozoon
cuniculi) 		4 / 6 PHE A  76
PHE A  40
HIS A  43
THR A  46
 None
 1.26A 3lb3B-3q87A:
undetectable		 3lb3B-3q87A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		4 / 8 PRO B 129
TYR B 157
ILE B 145
ILE B 159
 None
 0.85A 3p4wC-3q87B:
undetectable		 3p4wC-3q87B:
18.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q87_B_SAMB300_0
(N6 ADENINE SPECIFIC
DNA METHYLASE)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		12 / 12 TYR B   4
THR B  10
GLY B  31
SER B  33
ILE B  37
ASP B  51
LEU B  52
ASN B  53
ASP B  69
LEU B  70
ASN B  85
PRO B  87
 SAM  B 300 (-3.5A)
SAM  B 300 (-3.2A)
SAM  B 300 (-3.5A)
SAM  B 300 (-3.9A)
None
SAM  B 300 (-2.9A)
SAM  B 300 (-3.9A)
SAM  B 300 (-4.9A)
SAM  B 300 (-3.7A)
SAM  B 300 (-4.4A)
SAM  B 300 (-3.9A)
SAM  B 300 (-4.1A)
 0.02A 3q87B-3q87B:
36.7		 3q87B-3q87B:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DCM_A_SAMA401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE G)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		6 / 11 ASP B  29
GLY B  31
ILE B  37
ASP B  51
ASN B  85
PRO B  87
 SAM  B 300 ( 4.7A)
SAM  B 300 (-3.5A)
None
SAM  B 300 (-2.9A)
SAM  B 300 (-3.9A)
SAM  B 300 (-4.1A)
 0.41A 4dcmA-3q87B:
12.3		 4dcmA-3q87B:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		4 / 5 GLY B 161
LEU B  13
LEU B  22
LEU B  71
 None
 0.85A 4o8fA-3q87B:
undetectable		 4o8fA-3q87B:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 ASP B  29
GLY B  31
ASP B  51
LEU B  52
ASP B  69
 SAM  B 300 ( 4.7A)
SAM  B 300 (-3.5A)
SAM  B 300 (-2.9A)
SAM  B 300 (-3.9A)
SAM  B 300 (-3.7A)
 0.90A 4pghB-3q87B:
11.5		 4pghB-3q87B:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		4 / 8 GLY B 161
GLU B 162
GLU B  20
ALA B  16
 None
 0.75A 4rjdA-3q87B:
undetectable
4rjdB-3q87B:
undetectable		 4rjdA-3q87B:
22.94
4rjdB-3q87B:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WCX_C_SAMC503_0
(BIOTIN AND THIAMIN
SYNTHESIS ASSOCIATED)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 TYR B 141
GLY B 161
LEU B  30
LEU B  70
ALA B 113
 None
None
None
SAM  B 300 (-4.4A)
None
 1.24A 4wcxC-3q87B:
2.7		 4wcxC-3q87B:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		4 / 7 PRO B 129
TYR B 157
ILE B 145
ILE B 159
 None
 0.87A 5murB-3q87B:
undetectable		 5murB-3q87B:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		5 / 12 VAL B 111
PHE B 110
ILE B 107
ILE B 159
VAL B 114
 None
 0.91A 5uvmB-3q87B:
undetectable		 5uvmB-3q87B:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)		 3q87 N6 ADENINE SPECIFIC
DNA METHYLASE
(Encephalitozoon
cuniculi) 		3 / 3 ARG B 139
ARG B 135
ASP B 112
 None
 0.97A 6d8pA-3q87B:
3.1		 6d8pA-3q87B:
13.15