SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q8d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3q8d DNA REPAIR PROTEIN
RECO
(Escherichia
coli) 		4 / 8 PHE A 183
PHE A 148
LEU A 139
PHE A 172
 None
 0.94A 1wrlC-3q8dA:
undetectable
1wrlD-3q8dA:
undetectable		 1wrlC-3q8dA:
16.25
1wrlD-3q8dA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3q8d DNA REPAIR PROTEIN
RECO
(Escherichia
coli) 		4 / 7 PHE A 183
PHE A 148
LEU A 139
PHE A 172
 None
 0.89A 1wrlE-3q8dA:
undetectable
1wrlF-3q8dA:
undetectable		 1wrlE-3q8dA:
16.25
1wrlF-3q8dA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 3q8d DNA REPAIR PROTEIN
RECO
(Escherichia
coli) 		4 / 8 ARG A 194
PHE A 134
LEU A  96
LEU A 142
 None
 0.97A 2bfpB-3q8dA:
undetectable		 2bfpB-3q8dA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PBH_A_BEZA401_0
(TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT, PUTATIVE)		 3q8d DNA REPAIR PROTEIN
RECO
(Escherichia
coli) 		5 / 12 ILE A  84
THR A  85
THR A 126
ALA A 130
ARG A 132
 None
 0.99A 4pbhA-3q8dA:
undetectable		 4pbhA-3q8dA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3q8d DNA REPAIR PROTEIN
RECO
(Escherichia
coli) 		5 / 8 ALA A  36
LEU A  22
ALA A  49
LEU A  56
LEU A  58
 None
 0.92A 4z90A-3q8dA:
undetectable
4z90B-3q8dA:
undetectable
4z90C-3q8dA:
undetectable
4z90D-3q8dA:
1.2
4z90E-3q8dA:
undetectable		 4z90A-3q8dA:
17.55
4z90B-3q8dA:
17.55
4z90C-3q8dA:
17.55
4z90D-3q8dA:
17.55
4z90E-3q8dA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 3q8d DNA REPAIR PROTEIN
RECO
(Escherichia
coli) 		3 / 3 LEU A 109
SER A 107
PHE A 106
 None
 0.61A 6fgcA-3q8dA:
undetectable		 6fgcA-3q8dA:
20.90