SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 4 ILE A  46
MET A 105
VAL A 141
GLY A  48
 None
 1.21A 1e06B-3q94A:
undetectable		 1e06B-3q94A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 12 GLY A 274
ILE A  34
VAL A  45
GLY A  21
ILE A 230
 None
 0.66A 1hshA-3q94A:
undetectable		 1hshA-3q94A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 6 GLY A  21
ILE A  46
GLN A  22
VAL A 207
 None
None
13P  A 321 ( 4.8A)
None
 1.08A 1rs7B-3q94A:
undetectable		 1rs7B-3q94A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 8 LEU A  10
ASN A 231
GLU A 135
HIS A 209
 None
13P  A 321 (-4.1A)
None
ZN  A 301 ( 3.2A)
 1.02A 2bnnA-3q94A:
undetectable
2bnnB-3q94A:
undetectable		 2bnnA-3q94A:
21.96
2bnnB-3q94A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_C_ADNC903_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 12 ILE A 219
ALA A  13
VAL A 232
PHE A 279
SER A  43
 None
None
13P  A 321 (-3.7A)
None
None
 1.11A 2gl0A-3q94A:
undetectable
2gl0C-3q94A:
undetectable		 2gl0A-3q94A:
22.22
2gl0C-3q94A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 12 PHE A 279
SER A  43
ILE A 219
ALA A  13
VAL A 232
 None
None
None
None
13P  A 321 (-3.7A)
 1.19A 2gl0D-3q94A:
undetectable
2gl0E-3q94A:
undetectable		 2gl0D-3q94A:
22.22
2gl0E-3q94A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 12 GLY A 274
ILE A  34
VAL A  45
GLY A  21
ILE A 230
 None
 0.59A 2rkgA-3q94A:
undetectable		 2rkgA-3q94A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 12 GLY A 274
ILE A  34
VAL A  45
GLY A  21
ILE A 230
 None
 0.59A 2rkgB-3q94A:
undetectable		 2rkgB-3q94A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 8 LEU A 173
LEU A 206
VAL A 198
GLY A 203
 None
 0.76A 3dcjB-3q94A:
2.1		 3dcjB-3q94A:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		3 / 3 VAL A  78
VAL A  20
SER A 281
 None
 0.67A 3n8xB-3q94A:
undetectable		 3n8xB-3q94A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 8 ILE A  82
VAL A  67
THR A  31
ILE A  34
 None
 0.83A 3p4wC-3q94A:
undetectable		 3p4wC-3q94A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 6 ALA A 136
GLY A 169
LEU A 164
VAL A 165
 None
 0.90A 4dubB-3q94A:
undetectable		 4dubB-3q94A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 7 PHE A  23
PHE A 279
ASN A 233
GLY A 211
 None
None
13P  A 321 (-4.9A)
13P  A 321 (-3.9A)
 0.91A 4ejjA-3q94A:
undetectable		 4ejjA-3q94A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_A_SVRA301_1
(NUCLEOCAPSID PROTEIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 11 GLY A 211
ALA A 174
GLN A  22
PHE A 279
ILE A 219
 13P  A 321 (-3.9A)
None
13P  A 321 ( 4.8A)
None
None
 1.21A 4j4vA-3q94A:
undetectable		 4j4vA-3q94A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 11 GLY A 211
ALA A 174
GLN A  22
PHE A 279
ILE A 219
 13P  A 321 (-3.9A)
None
13P  A 321 ( 4.8A)
None
None
 1.23A 4j4vD-3q94A:
undetectable
4j4vE-3q94A:
undetectable		 4j4vD-3q94A:
22.97
4j4vE-3q94A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 5 GLY A 139
THR A 140
GLY A 178
GLU A 137
 None
 1.05A 4v20A-3q94A:
undetectable		 4v20A-3q94A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 5 GLU A 166
THR A 202
THR A 120
HIS A 111
 None
None
None
ZN  A 302 (-3.5A)
 1.24A 5axaA-3q94A:
undetectable		 5axaA-3q94A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 5 GLU A 166
THR A 202
THR A 120
HIS A 111
 None
None
None
ZN  A 302 (-3.5A)
 1.24A 5axaC-3q94A:
undetectable		 5axaC-3q94A:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 12 GLY A 274
ILE A  34
VAL A  45
GLY A  21
ILE A 230
 None
 0.72A 5e5jA-3q94A:
undetectable		 5e5jA-3q94A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 12 GLY A 274
ILE A  34
VAL A  45
GLY A  21
ILE A 230
 None
 0.73A 5e5kA-3q94A:
undetectable		 5e5kA-3q94A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		4 / 8 ILE A  82
VAL A  67
THR A  31
ILE A  34
 None
 0.69A 5mzrE-3q94A:
undetectable		 5mzrE-3q94A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 12 GLY A 274
ILE A  34
VAL A  45
GLY A  21
ILE A 230
 None
 0.75A 5t8hA-3q94A:
undetectable		 5t8hA-3q94A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 12 GLY A 274
ILE A  34
VAL A  45
GLY A  21
ILE A 230
 None
 0.82A 5t8hB-3q94A:
undetectable		 5t8hB-3q94A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		3 / 3 GLU A 125
TYR A 126
ARG A 130
 None
 0.79A 5uunB-3q94A:
undetectable		 5uunB-3q94A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 3q94 FRUCTOSE-BISPHOSPHAT
E ALDOLASE, CLASS II
(Bacillus
anthracis) 		5 / 10 PRO A  44
PRO A  79
ALA A  37
GLY A 274
ILE A 273
 None
 1.35A 5vyhA-3q94A:
undetectable		 5vyhA-3q94A:
20.61