SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		3 / 3 ALA A 215
VAL A 194
TRP A 258
 None
 0.86A 1av2C-3q9cA:
undetectable
1av2D-3q9cA:
undetectable		 1av2C-3q9cA:
2.68
1av2D-3q9cA:
2.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 11 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.44A 1c3sA-3q9cA:
36.9		 1c3sA-3q9cA:
27.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 7 HIS A 158
LEU A 281
SER A 280
ASP A 193
 Q9C  A 401 (-4.2A)
None
None
K  A 342 (-3.2A)
 1.04A 1ismB-3q9cA:
undetectable		 1ismB-3q9cA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 12 HIS A 158
THR A 285
GLY A 282
GLU A 320
GLY A 321
HIS A 197
 Q9C  A 401 (-4.2A)
None
None
None
Q9C  A 401 (-3.6A)
ZN  A 343 (-3.4A)
 1.40A 1n2xB-3q9cA:
3.9		 1n2xB-3q9cA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.45A 1t69A-3q9cA:
35.6		 1t69A-3q9cA:
25.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		3 / 3 ALA A 215
VAL A 194
TRP A 258
 None
 0.84A 1w5uC-3q9cA:
undetectable
1w5uD-3q9cA:
undetectable		 1w5uC-3q9cA:
2.68
1w5uD-3q9cA:
2.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 11 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.39A 1zz1A-3q9cA:
41.9		 1zz1A-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 11 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.25A 1zz1A-3q9cA:
41.9		 1zz1A-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.38A 1zz1B-3q9cA:
42.3
1zz1C-3q9cA:
42.1		 1zz1B-3q9cA:
29.89
1zz1C-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.42A 1zz1C-3q9cA:
42.1		 1zz1C-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_D_SHHD2752_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 9 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.40A 1zz1D-3q9cA:
41.9		 1zz1D-3q9cA:
29.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 11 THR A 124
ALA A 160
PRO A 155
ILE A 205
ASP A 204
 None
 0.97A 2admB-3q9cA:
undetectable		 2admB-3q9cA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 GLY A 157
TYR A 168
GLY A 321
ILE A 171
ALA A 160
 None
Q9C  A 401 (-3.7A)
Q9C  A 401 (-3.6A)
None
None
 1.11A 2plwA-3q9cA:
2.2		 2plwA-3q9cA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 8 LEU A 262
LEU A 281
VAL A 339
GLY A 338
 None
 0.91A 2po5B-3q9cA:
3.0		 2po5B-3q9cA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 7 SER A 280
PHE A 214
ILE A 191
GLY A 199
 None
 0.99A 2y7kA-3q9cA:
undetectable		 2y7kA-3q9cA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 5 HIS A 158
ASP A 195
HIS A 197
ASP A 284
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
 0.16A 3c0zA-3q9cA:
39.4		 3c0zA-3q9cA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 8 HIS A 158
ASP A 195
ASP A 284
GLY A 282
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-2.7A)
None
 0.90A 3c0zB-3q9cA:
39.3		 3c0zB-3q9cA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 8 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
 0.29A 3c0zB-3q9cA:
39.3		 3c0zB-3q9cA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 6 HIS A 158
ASP A 195
HIS A 197
ASP A 284
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
 0.23A 3c0zC-3q9cA:
39.3		 3c0zC-3q9cA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 ASN A 173
ALA A 127
ALA A  33
GLY A 321
THR A 118
 None
None
None
Q9C  A 401 (-3.6A)
None
 0.93A 3c6gA-3q9cA:
undetectable		 3c6gA-3q9cA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 5 ASN A 173
ALA A  33
GLY A 321
THR A 118
 None
None
Q9C  A 401 (-3.6A)
None
 0.82A 3dl9A-3q9cA:
undetectable		 3dl9A-3q9cA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 PHE A 170
GLY A 201
ILE A 120
PRO A 155
ASN A 173
 None
 1.14A 3eeoA-3q9cA:
undetectable		 3eeoA-3q9cA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_A_ERYA195_0
(REPRESSOR PROTEIN
MPHR(A))		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 TYR A 247
LEU A 262
SER A 265
VAL A 194
ILE A 308
 None
 1.20A 3frqA-3q9cA:
undetectable		 3frqA-3q9cA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_D_HCZD800_1
(GLUTAMATE RECEPTOR 2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 9 ILE A 277
SER A 280
SER A 216
LEU A 266
SER A 265
 None
None
K  A 342 (-2.8A)
None
None
 1.48A 3ijxB-3q9cA:
0.0
3ijxD-3q9cA:
0.4		 3ijxB-3q9cA:
20.62
3ijxD-3q9cA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 4 GLY A 324
TYR A 323
GLY A 322
ASP A 284
 None
None
None
ZN  A 343 (-2.7A)
 1.24A 3kl3A-3q9cA:
undetectable		 3kl3A-3q9cA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		3 / 3 ALA A 215
VAL A 194
TRP A 258
 None
 0.85A 3l8lC-3q9cA:
undetectable
3l8lD-3q9cA:
undetectable		 3l8lC-3q9cA:
2.68
3l8lD-3q9cA:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		3 / 3 HIS A 198
PHE A 293
PHE A 294
 None
 0.76A 3lk0D-3q9cA:
undetectable		 3lk0D-3q9cA:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 12 SER A 280
ILE A 191
ALA A 175
ILE A 171
GLU A  28
GLY A 166
 None
 1.49A 3nxuA-3q9cA:
undetectable		 3nxuA-3q9cA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 8 LEU A 229
ALA A 215
THR A 244
GLY A 161
 None
 0.87A 3ny4A-3q9cA:
undetectable		 3ny4A-3q9cA:
29.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 5 VAL A 194
PHE A 214
ILE A 191
PHE A 206
 None
 0.85A 3owxB-3q9cA:
undetectable		 3owxB-3q9cA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A  63
ILE A 191
GLY A 201
ALA A 160
ALA A 174
 None
 0.95A 3sudC-3q9cA:
undetectable		 3sudC-3q9cA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 4 ASN A 200
ALA A 159
GLY A 201
THR A 202
 None
 1.21A 4bboC-3q9cA:
undetectable		 4bboC-3q9cA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 10 HIS A 158
ASP A 195
HIS A 197
ASP A 284
PRO A 290
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
Q9C  A 401 (-3.6A)
None
 0.53A 4bz6A-3q9cA:
35.5		 4bz6A-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 10 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4bz6A-3q9cA:
35.5		 4bz6A-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 10 HIS A 158
HIS A 197
ASP A 284
PRO A 290
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 0.95A 4bz6A-3q9cA:
35.5		 4bz6A-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
PRO A 290
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
Q9C  A 401 (-3.6A)
None
 0.62A 4bz6A-3q9cA:
35.4
4bz6B-3q9cA:
35.3		 4bz6A-3q9cA:
22.01
4bz6B-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.22A 4bz6A-3q9cA:
35.4
4bz6B-3q9cA:
35.3		 4bz6A-3q9cA:
22.01
4bz6B-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
PRO A 290
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 0.97A 4bz6A-3q9cA:
35.4
4bz6B-3q9cA:
35.3		 4bz6A-3q9cA:
22.01
4bz6B-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		9 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
PRO A 290
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
Q9C  A 401 (-3.6A)
None
 0.65A 4bz6C-3q9cA:
35.4		 4bz6C-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.22A 4bz6C-3q9cA:
35.4		 4bz6C-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
PRO A 290
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 0.96A 4bz6C-3q9cA:
35.4		 4bz6C-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 10 HIS A 158
ASP A 195
HIS A 197
ASP A 284
PRO A 290
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
Q9C  A 401 (-3.6A)
None
 0.55A 4bz6D-3q9cA:
35.4		 4bz6D-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 10 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4bz6D-3q9cA:
35.4		 4bz6D-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 10 HIS A 158
HIS A 197
ASP A 284
PRO A 290
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 0.98A 4bz6D-3q9cA:
35.4		 4bz6D-3q9cA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 LEU A 281
VAL A 194
ALA A 190
SER A 265
THR A 307
 None
 1.43A 4iarA-3q9cA:
undetectable		 4iarA-3q9cA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 8 HIS A 146
ASP A  47
ASP A 137
ILE A   4
 None
 0.98A 4k0bA-3q9cA:
undetectable		 4k0bA-3q9cA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_A_LYAA304_1
(FOLATE RECEPTOR BETA)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 TYR A 323
SER A 280
HIS A 197
GLY A 230
SER A 292
 None
None
ZN  A 343 (-3.4A)
None
None
 1.46A 4kn2A-3q9cA:
undetectable		 4kn2A-3q9cA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.36A 4lxzA-3q9cA:
38.2		 4lxzA-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.21A 4lxzA-3q9cA:
38.2		 4lxzA-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 11 HIS A 158
ASP A 195
HIS A 197
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.34A 4lxzB-3q9cA:
38.1		 4lxzB-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 11 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.21A 4lxzB-3q9cA:
38.1		 4lxzB-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.43A 4lxzC-3q9cA:
38.2		 4lxzC-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 1.03A 4lxzC-3q9cA:
38.2		 4lxzC-3q9cA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.43A 4qa0A-3q9cA:
35.8		 4qa0A-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4qa0A-3q9cA:
35.8		 4qa0A-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 197
PHE A 225
ASP A 284
GLY A 322
TYR A 323
 ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
None
 1.32A 4qa0A-3q9cA:
35.8		 4qa0A-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 11 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.46A 4qa0B-3q9cA:
35.7		 4qa0B-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 11 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4qa0B-3q9cA:
35.7		 4qa0B-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 11 HIS A 197
PHE A 225
ASP A 284
GLY A 322
TYR A 323
 ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
None
 1.31A 4qa0B-3q9cA:
35.7		 4qa0B-3q9cA:
25.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.49A 4qa2A-3q9cA:
35.2		 4qa2A-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.24A 4qa2A-3q9cA:
35.2		 4qa2A-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 197
PHE A 225
ASP A 284
GLY A 322
TYR A 323
 ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
None
 1.31A 4qa2A-3q9cA:
35.2		 4qa2A-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		8 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.43A 4qa2B-3q9cA:
36.0		 4qa2B-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.23A 4qa2B-3q9cA:
36.0		 4qa2B-3q9cA:
25.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.30A 5eeiA-3q9cA:
41.4		 5eeiA-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
GLY A 167
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
Q9C  A 401 (-3.7A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.31A 5eeiB-3q9cA:
41.2		 5eeiB-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
ASP A 195
HIS A 197
ASP A 284
GLY A 282
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
 1.28A 5eenA-3q9cA:
41.2		 5eenA-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		7 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
GLY A 321
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
Q9C  A 401 (-3.6A)
None
 0.32A 5eenA-3q9cA:
41.2		 5eenA-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 HIS A 158
HIS A 197
ASP A 284
GLY A 322
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-3.4A)
ZN  A 343 (-2.7A)
None
None
 1.27A 5eenA-3q9cA:
41.2		 5eenA-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.33A 5eenB-3q9cA:
41.2		 5eenB-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.27A 5ef8A-3q9cA:
41.4		 5ef8A-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		6 / 12 HIS A 158
ASP A 195
HIS A 197
PHE A 225
ASP A 284
TYR A 323
 Q9C  A 401 (-4.2A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
Q9C  A 401 (-3.8A)
ZN  A 343 (-2.7A)
None
 0.29A 5ef8B-3q9cA:
41.3		 5ef8B-3q9cA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		5 / 12 ILE A 291
ASP A 195
HIS A 197
GLU A 320
ILE A 328
 Q9C  A 401 ( 4.4A)
ZN  A 343 (-2.3A)
ZN  A 343 (-3.4A)
None
None
 1.43A 5igwA-3q9cA:
undetectable		 5igwA-3q9cA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 8 GLY A 201
ASP A 193
ASP A 195
HIS A 218
 None
K  A 342 (-3.2A)
ZN  A 343 (-2.3A)
None
 0.94A 6ag0A-3q9cA:
undetectable		 6ag0A-3q9cA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 8 TYR A 247
GLY A 230
ASP A 193
ASP A 195
 None
None
K  A 342 (-3.2A)
ZN  A 343 (-2.3A)
 1.02A 6ag0C-3q9cA:
undetectable		 6ag0C-3q9cA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA607_1
(SERUM ALBUMIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 7 ASP A 140
ALA A 144
LYS A 184
LEU A 181
 None
 0.78A 6ci6A-3q9cA:
undetectable		 6ci6A-3q9cA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		4 / 5 ILE A 136
GLN A 179
THR A  58
LEU A 316
 None
 1.15A 6f3mD-3q9cA:
3.2		 6f3mD-3q9cA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		3 / 3 HIS A  54
ARG A 180
ILE A 136
 None
 0.82A 6fgdA-3q9cA:
3.0		 6fgdA-3q9cA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 3q9c ACETYLPOLYAMINE
AMIDOHYDROLASE
(Mycoplana
ramosa) 		3 / 3 LYS A  10
SER A 130
SER A   6
 None
 1.10A 6gbfA-3q9cA:
undetectable		 6gbfA-3q9cA:
25.00