SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 ILE A 507
ALA A 520
GLN A 356
ILE A 429
THR A 518
 None
None
NAD  A 700 (-3.6A)
None
None
 1.11A 1dhfA-3q9oA:
undetectable		 1dhfA-3q9oA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_A_NCAA700_0
(EXOTOXIN A)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		6 / 7 HIS A 460
GLY A 461
TYR A 493
ALA A 501
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 (-3.5A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.36A 1dmaA-3q9oA:
24.9		 1dmaA-3q9oA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		6 / 6 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 ( 3.9A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.43A 1dmaB-3q9oA:
23.2		 1dmaB-3q9oA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 6 ILE A  93
GLU A 258
LEU A 390
ASP A 388
 None
 0.95A 1mt1B-3q9oA:
undetectable
1mt1C-3q9oA:
undetectable		 1mt1B-3q9oA:
10.24
1mt1C-3q9oA:
6.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 GLY A 418
VAL A 593
SER A 420
ILE A 595
 None
 0.91A 1pk7B-3q9oA:
undetectable		 1pk7B-3q9oA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		3 / 3 MET A  46
ASN A 164
GLN A  26
 None
 1.04A 1xoqB-3q9oA:
undetectable		 1xoqB-3q9oA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 MET A  46
LEU A  29
SER A  63
GLN A  26
ILE A   7
 None
 1.37A 1xotA-3q9oA:
undetectable		 1xotA-3q9oA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		3 / 3 SER A 323
VAL A 336
LEU A 340
 None
 0.74A 1yajG-3q9oA:
undetectable		 1yajG-3q9oA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 5 PRO A  85
VAL A  80
ASN A  81
VAL A  88
 None
 1.07A 1z2bC-3q9oA:
undetectable		 1z2bC-3q9oA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		3 / 3 LYS A 190
ASP A  34
ASP A  38
 None
 0.99A 2br4D-3q9oA:
undetectable		 2br4D-3q9oA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		3 / 3 SER A 148
HIS A 275
ASP A 297
 None
 0.78A 2oxtA-3q9oA:
undetectable		 2oxtA-3q9oA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 7 ALA A 444
THR A 445
ALA A 448
PRO A 423
 None
 0.96A 2ql8A-3q9oA:
undetectable
2ql8B-3q9oA:
undetectable		 2ql8A-3q9oA:
13.93
2ql8B-3q9oA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 7 GLY A  40
GLY A 120
GLU A 237
ALA A 188
 None
 0.81A 3fpjB-3q9oA:
undetectable		 3fpjB-3q9oA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 ASP A 135
ILE A 216
ILE A 252
VAL A 143
PRO A 144
 None
 0.91A 3kpdC-3q9oA:
undetectable		 3kpdC-3q9oA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 ILE A 140
ILE A 216
ILE A 252
VAL A 143
PRO A 144
 None
 0.89A 3kpdC-3q9oA:
undetectable		 3kpdC-3q9oA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		3 / 3 THR A 247
ASP A 135
GLU A 110
 None
 0.79A 3qowA-3q9oA:
undetectable		 3qowA-3q9oA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 ( 3.9A)
NAD  A 700 (-3.4A)
 0.51A 3u9hA-3q9oA:
5.7		 3u9hA-3q9oA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 HIS A 460
GLY A 461
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.70A 3u9hA-3q9oA:
5.7		 3u9hA-3q9oA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 ( 3.9A)
NAD  A 700 (-3.4A)
 0.54A 3u9hB-3q9oA:
5.6		 3u9hB-3q9oA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_B_NCAB1164_0
(TANKYRASE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 HIS A 460
GLY A 461
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.64A 3u9hB-3q9oA:
5.6		 3u9hB-3q9oA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 VAL A 434
ILE A 429
GLU A 617
ILE A 609
VAL A 471
 None
 1.10A 4a97B-3q9oA:
undetectable
4a97C-3q9oA:
undetectable		 4a97B-3q9oA:
18.53
4a97C-3q9oA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		6 / 6 HIS A 460
GLY A 461
TYR A 493
ALA A 501
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 (-3.5A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.55A 4ae1A-3q9oA:
9.7		 4ae1A-3q9oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 5 HIS A 460
GLY A 461
TYR A 493
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.52A 4ae1B-3q9oA:
7.8		 4ae1B-3q9oA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 ( 3.9A)
NAD  A 700 (-3.4A)
 0.43A 4bjcA-3q9oA:
5.4		 4bjcA-3q9oA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 HIS A 460
GLY A 461
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.60A 4bjcA-3q9oA:
5.4		 4bjcA-3q9oA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 6 GLY A 510
ARG A 506
GLU A 605
ARG A 522
 None
 1.37A 4bqfA-3q9oA:
undetectable		 4bqfA-3q9oA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 ASN A 114
ASP A 132
VAL A 211
LEU A 116
 None
 1.05A 4f8hA-3q9oA:
undetectable
4f8hB-3q9oA:
undetectable		 4f8hA-3q9oA:
19.18
4f8hB-3q9oA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 ASN A 114
ASP A 132
VAL A 211
LEU A 116
 None
 1.08A 4f8hB-3q9oA:
undetectable
4f8hC-3q9oA:
undetectable		 4f8hB-3q9oA:
19.18
4f8hC-3q9oA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 ASN A 114
ASP A 132
VAL A 211
LEU A 116
 None
 1.06A 4f8hC-3q9oA:
undetectable
4f8hD-3q9oA:
undetectable		 4f8hC-3q9oA:
19.18
4f8hD-3q9oA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 ASN A 114
ASP A 132
VAL A 211
LEU A 116
 None
 1.05A 4f8hD-3q9oA:
undetectable
4f8hE-3q9oA:
undetectable		 4f8hD-3q9oA:
19.18
4f8hE-3q9oA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 VAL A 211
LEU A 116
ASN A 114
ASP A 132
 None
 1.06A 4f8hA-3q9oA:
undetectable
4f8hE-3q9oA:
undetectable		 4f8hA-3q9oA:
19.18
4f8hE-3q9oA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_A_NCAA1201_0
(TANKYRASE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		6 / 7 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 ( 3.9A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.63A 4hyfA-3q9oA:
5.6		 4hyfA-3q9oA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_B_NCAB1201_0
(TANKYRASE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		6 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 ( 3.9A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.64A 4hyfB-3q9oA:
5.7		 4hyfB-3q9oA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYF_C_NCAC1201_0
(TANKYRASE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		6 / 8 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 ( 3.9A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.57A 4hyfC-3q9oA:
5.3		 4hyfC-3q9oA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 GLY A 458
PRO A 624
PHE A 541
ILE A 533
 None
 0.80A 4j4vC-3q9oA:
undetectable		 4j4vC-3q9oA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 6 ASN A 602
GLU A 605
TYR A 604
GLU A 606
 None
 1.39A 4mi4A-3q9oA:
undetectable		 4mi4A-3q9oA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 TYR A 365
GLY A 374
SER A 381
GLY A 383
THR A 370
 GOL  A 801 (-4.1A)
None
GOL  A 801 (-2.6A)
None
None
 1.03A 4mm8A-3q9oA:
undetectable		 4mm8A-3q9oA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 8 LEU A 207
LEU A 210
VAL A 211
ILE A 140
 None
 0.96A 4oj4A-3q9oA:
undetectable		 4oj4A-3q9oA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 GLY A 204
GLN A 259
GLU A 414
SER A 148
ILE A 261
 None
 1.10A 4pb1A-3q9oA:
undetectable		 4pb1A-3q9oA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 GLY A 204
GLN A 259
GLU A 414
SER A 148
ILE A 261
 None
 1.10A 4pd9A-3q9oA:
undetectable		 4pd9A-3q9oA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 9 ALA A 592
ALA A 589
ILE A 595
GLY A 418
ALA A 594
 None
 1.18A 4qvqK-3q9oA:
undetectable
4qvqL-3q9oA:
undetectable		 4qvqK-3q9oA:
14.59
4qvqL-3q9oA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 9 ALA A 592
ALA A 589
ILE A 595
GLY A 418
ALA A 594
 None
 1.17A 4qvqY-3q9oA:
undetectable
4qvqZ-3q9oA:
undetectable		 4qvqY-3q9oA:
14.59
4qvqZ-3q9oA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 ARG A 106
ALA A  75
SER A  63
GLY A  61
GLN A  52
 None
 1.20A 4r29A-3q9oA:
undetectable		 4r29A-3q9oA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_A_RPBA1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		6 / 11 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 ( 3.9A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.49A 4rv6A-3q9oA:
4.7		 4rv6A-3q9oA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RV6_B_RPBB1103_1
(POLY [ADP-RIBOSE]
POLYMERASE 1)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		6 / 11 HIS A 460
GLY A 461
TYR A 493
ALA A 495
TYR A 504
GLU A 581
 NAD  A 700 (-3.8A)
NAD  A 700 (-3.7A)
NAD  A 700 ( 3.7A)
NAD  A 700 ( 3.9A)
NAD  A 700 (-3.4A)
NAD  A 700 (-3.2A)
 0.48A 4rv6B-3q9oA:
5.6		 4rv6B-3q9oA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 6 ILE A 584
LEU A 492
ARG A 543
THR A 496
 None
NAD  A 700 ( 4.7A)
None
None
 1.07A 5b1aN-3q9oA:
undetectable
5b1aW-3q9oA:
undetectable		 5b1aN-3q9oA:
20.91
5b1aW-3q9oA:
7.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		3 / 3 THR A 247
ASP A 135
GLU A 110
 None
 0.77A 5fa8A-3q9oA:
undetectable		 5fa8A-3q9oA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 12 ASN A 463
GLN A 356
VAL A 527
LEU A 529
HIS A 460
 NAD  A 700 ( 4.6A)
NAD  A 700 (-3.6A)
None
None
NAD  A 700 (-3.8A)
 1.19A 5kocB-3q9oA:
undetectable		 5kocB-3q9oA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZP_A_CFFA2401_1
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		5 / 9 ILE A 149
VAL A 117
PHE A  70
GLU A  69
ASN A 164
 None
 1.39A 5mzpA-3q9oA:
undetectable		 5mzpA-3q9oA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 5 TYR A 542
LYS A 627
LEU A 538
GLU A 539
 None
 1.27A 5weaA-3q9oA:
undetectable		 5weaA-3q9oA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		3 / 3 SER A 621
HIS A 446
TYR A 532
 None
 1.00A 5y2tA-3q9oA:
undetectable		 5y2tA-3q9oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRF_D_EVPD101_1
()		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 5 GLY A 279
ASP A 297
ARG A 419
GLN A 356
 None
None
None
NAD  A 700 (-3.6A)
 1.26A 5zrfB-3q9oA:
undetectable		 5zrfB-3q9oA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_B_ADNB505_2
(-)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 4 GLN A 363
THR A 359
HIS A 460
LEU A 492
 GOL  A 802 (-3.3A)
None
NAD  A 700 (-3.8A)
NAD  A 700 ( 4.7A)
 1.24A 6f3nB-3q9oA:
undetectable		 6f3nB-3q9oA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3q9o EXOTOXIN A
(Vibrio
cholerae) 		4 / 6 VAL A 527
PRO A 600
ILE A 599
GLU A 617
 None
 1.21A 6h7uA-3q9oA:
undetectable		 6h7uA-3q9oA:
21.91