SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3q9s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_F_9CRF1600_1 (RETINOIC ACID RECEPTOR, BETA)	3q9s	DNA-BINDING RESPONSE REGULATOR (Deinococcus radiodurans)	5 / 12	LEU A 157 LEU A 160 ILE A 161 LEU A 131 LEU A 196	None	0.97A	1xdkF-3q9sA: undetectable	1xdkF-3q9sA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SU9_A_ACTA426_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	3q9s	DNA-BINDING RESPONSE REGULATOR (Deinococcus radiodurans)	3 / 3	GLN A 4 GLU A 3 LYS A 3	None	1.15A	3su9A-3q9sA: undetectable	3su9A-3q9sA: 23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UUU_B_SAMB1548_0 (CYSTATHIONINE BETA-SYNTHASE)	3q9s	DNA-BINDING RESPONSE REGULATOR (Deinococcus radiodurans)	5 / 11	SER A 150 ASP A 99 GLN A 117 ILE A 177 ASP A 155	None	1.19A	4uuuB-3q9sA: undetectable	4uuuB-3q9sA: 25.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE1_A_X2NA602_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3q9s	DNA-BINDING RESPONSE REGULATOR (Deinococcus radiodurans)	4 / 5	VAL A 79 ILE A 161 PRO A 151 THR A 122	None	1.19A	4ze1A-3q9sA: undetectable	4ze1A-3q9sA: 18.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XDK_F_9CRF1600_1","RETINOIC ACID RECEPTOR, BETA","3q9s","DNA-BINDING RESPONSE REGULATOR","Deinococcus radiodurans",5,"LEU A 157;LEU A 160;ILE A 161;LEU A 131;LEU A 196","None","0.97A","1xdkF-3q9sA:undetectable","1xdkF-3q9sA:21.15"],["3SU9_A_ACTA426_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","3q9s","DNA-BINDING RESPONSE REGULATOR","Deinococcus radiodurans",3,"GLN A   4;GLU A   3;LYS A   3","None","1.15A","3su9A-3q9sA:undetectable","3su9A-3q9sA:23.19"],["4UUU_B_SAMB1548_0","CYSTATHIONINE BETA-SYNTHASE","3q9s","DNA-BINDING RESPONSE REGULATOR","Deinococcus radiodurans",5,"SER A 150;ASP A  99;GLN A 117;ILE A 177;ASP A 155","None","1.19A","4uuuB-3q9sA:undetectable","4uuuB-3q9sA:25.88"],["4ZE1_A_X2NA602_2","LANOSTEROL 14-ALPHA DEMETHYLASE","3q9s","DNA-BINDING RESPONSE REGULATOR","Deinococcus radiodurans",4,"VAL A  79;ILE A 161;PRO A 151;THR A 122","None","1.19A","4ze1A-3q9sA:undetectable","4ze1A-3q9sA:18.11"]]