SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qan'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_1
(FTSJ)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 ASP A 331
ASP A 334
ASP A 429
 None
 0.66A 1eizA-3qanA:
undetectable		 1eizA-3qanA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_1
(FTSJ)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 ASP A 331
ASP A 334
ASP A 429
 None
 0.67A 1ej0A-3qanA:
3.7		 1ej0A-3qanA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 ARG A 265
GLY A 238
ASP A 243
 None
 0.35A 1kf6A-3qanA:
3.4
1kf6B-3qanA:
undetectable		 1kf6A-3qanA:
20.94
1kf6B-3qanA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 11 VAL A 422
ALA A 423
PHE A 424
LEU A 337
MET A 385
 None
 1.27A 1uduA-3qanA:
undetectable		 1uduA-3qanA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 12 ILE A 108
ILE A 107
ALA A 106
ARG A 109
LEU A 141
 None
 1.09A 1xzxX-3qanA:
undetectable		 1xzxX-3qanA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 9 LEU A 141
VAL A 189
GLY A 190
VAL A 202
ILE A 231
 None
 1.35A 2a1oB-3qanA:
undetectable		 2a1oB-3qanA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 LYS A 495
ASP A 291
ASN A 467
 None
 0.80A 2bm9A-3qanA:
3.8		 2bm9A-3qanA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 ASP A 296
ASP A 331
ASP A 431
 None
 0.64A 2igtA-3qanA:
4.4		 2igtA-3qanA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 ASP A 296
ASP A 331
ASP A 431
 None
 0.68A 2igtB-3qanA:
undetectable		 2igtB-3qanA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VTB_B_ACTB1500_0
(CRYPTOCHROME DASH)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		4 / 4 ARG A 110
PHE A 115
VAL A 220
ASP A 223
 None
 1.45A 2vtbB-3qanA:
0.3		 2vtbB-3qanA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 10 VAL A 176
ILE A 178
LEU A  39
GLY A 236
ALA A  70
 None
 1.19A 2xf3A-3qanA:
undetectable		 2xf3A-3qanA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B500_1
(ORF12)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 9 VAL A 176
ILE A 178
LEU A  39
GLY A 236
ALA A  70
 None
 1.20A 2xf3B-3qanA:
undetectable		 2xf3B-3qanA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		4 / 8 VAL A 176
LEU A  39
GLY A 236
ALA A  70
 None
 0.79A 2xfsA-3qanA:
undetectable		 2xfsA-3qanA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B500_1
(ORF12)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 9 VAL A 176
ILE A 178
LEU A  39
GLY A 236
ALA A  70
 None
 1.19A 2xfsB-3qanA:
undetectable		 2xfsB-3qanA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		4 / 8 VAL A 176
LEU A  39
GLY A 236
ALA A  70
 None
 0.77A 2xh9A-3qanA:
undetectable		 2xh9A-3qanA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1436_1
(ORF12)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 9 VAL A 176
ILE A 178
LEU A  39
GLY A 236
ALA A  70
 None
 1.21A 2xh9B-3qanA:
undetectable		 2xh9B-3qanA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOB_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 12 MET A 385
PHE A 424
ALA A 423
THR A 401
GLY A 378
 None
 1.34A 3aobC-3qanA:
undetectable		 3aobC-3qanA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 ASP A 331
ASP A 334
ASP A 429
 None
 0.70A 3douA-3qanA:
2.9		 3douA-3qanA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 9 LEU A 204
ILE A 100
ILE A 108
ALA A 192
ILE A 231
 None
 0.98A 3el0B-3qanA:
undetectable		 3el0B-3qanA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 VAL A 213
LYS A 216
HIS A 113
 None
 0.95A 3elzA-3qanA:
undetectable		 3elzA-3qanA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_2
(PROTEIN S100-A4)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		4 / 6 LEU A 185
SER A 116
PHE A 115
ILE A 108
 None
 0.97A 3ko0B-3qanA:
undetectable		 3ko0B-3qanA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 12 LEU A 185
SER A 116
PHE A 115
ILE A 108
PHE A  22
 None
 1.18A 3ko0G-3qanA:
undetectable
3ko0H-3qanA:
undetectable
3ko0I-3qanA:
undetectable
3ko0J-3qanA:
undetectable		 3ko0G-3qanA:
12.48
3ko0H-3qanA:
12.48
3ko0I-3qanA:
12.48
3ko0J-3qanA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_1
(PROTEIN S100-A4)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		4 / 6 LEU A 185
SER A 116
PHE A 115
ILE A 108
 None
 0.99A 3ko0S-3qanA:
undetectable		 3ko0S-3qanA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 12 GLY A 124
ASP A 364
ILE A 363
GLY A 360
PHE A 397
 None
 1.18A 3ps9A-3qanA:
4.2		 3ps9A-3qanA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 PHE A 487
LYS A 495
SER A 494
 None
 1.06A 3tyeB-3qanA:
undetectable		 3tyeB-3qanA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		4 / 7 LEU A 221
ARG A 111
PRO A 206
VAL A 213
 None
 1.15A 4klrA-3qanA:
2.2		 4klrA-3qanA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		4 / 7 THR A 292
ARG A 325
PHE A 424
SER A 425
 None
 1.34A 4o4dA-3qanA:
undetectable		 4o4dA-3qanA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 GLY A 360
PRO A 361
GLN A 318
 None
 0.36A 4oltB-3qanA:
undetectable		 4oltB-3qanA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		3 / 3 GLY A 360
PRO A 361
GLN A 318
 None
 0.25A 4qwpB-3qanA:
undetectable		 4qwpB-3qanA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 12 ILE A 107
ALA A 106
ARG A 109
ARG A 146
LEU A 141
 None
 1.45A 4zo1X-3qanA:
undetectable		 4zo1X-3qanA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		5 / 12 GLU A 416
LEU A 444
GLY A 323
ALA A 477
PHE A 183
 None
 1.45A 5kc4A-3qanA:
undetectable		 5kc4A-3qanA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA604_0
(SERUM ALBUMIN)		 3qan 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE
1
(Bacillus
halodurans) 		4 / 8 LYS A  20
GLY A  27
LEU A  26
ALA A 117
 None
 0.75A 6mdqA-3qanA:
2.2		 6mdqA-3qanA:
10.54