SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qax'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		5 / 12 GLY A 196
LEU A 193
THR A 227
ILE A 223
PHE A  35
 None
 1.40A 1p93B-3qaxA:
undetectable		 1p93B-3qaxA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		4 / 6 TYR A  20
GLU A 165
PRO A 166
VAL A 171
 ARG  A 600 (-3.4A)
ARG  A 600 (-3.1A)
None
None
 1.12A 1q13A-3qaxA:
undetectable		 1q13A-3qaxA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		5 / 10 LEU A 197
GLY A 196
LEU A  89
LEU A  90
LEU A  65
 None
 1.04A 2f8dB-3qaxA:
5.6		 2f8dB-3qaxA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		4 / 6 ALA A  40
ILE A  37
LEU A  51
ALA A  72
 None
 0.84A 3r9sC-3qaxA:
undetectable		 3r9sC-3qaxA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_A_MIYA392_1
(TETX2 PROTEIN)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		5 / 9 LEU A 232
TYR A  93
SER A  78
GLN A 129
VAL A 192
 None
None
ARG  A 600 (-2.6A)
ARG  A 600 ( 4.0A)
None
 1.41A 4a99A-3qaxA:
0.0
4a99C-3qaxA:
0.0		 4a99A-3qaxA:
21.20
4a99C-3qaxA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		3 / 3 GLU A 130
GLY A 126
SER A 143
 None
 0.68A 4b53B-3qaxA:
undetectable		 4b53B-3qaxA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		4 / 6 GLU A 206
ILE A 210
GLU A  24
VAL A  53
 None
None
ARG  A 600 (-3.9A)
None
 1.04A 4ejwB-3qaxA:
undetectable		 4ejwB-3qaxA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		5 / 12 GLN A 124
THR A 127
TYR A 128
SER A  78
LEU A 164
 ARG  A 600 (-3.6A)
ARG  A 600 (-4.3A)
ARG  A 600 (-4.7A)
ARG  A 600 (-2.6A)
None
 1.41A 4qztA-3qaxA:
undetectable		 4qztA-3qaxA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		4 / 5 ALA A  72
HIS A  68
ALA A 200
GLU A 206
 None
 1.44A 5a06C-3qaxA:
undetectable
5a06D-3qaxA:
undetectable		 5a06C-3qaxA:
23.55
5a06D-3qaxA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 3qax PROBABLE ABC
TRANSPORTER
ARGININE-BINDING
PROTEIN ARTJ
(Chlamydia
pneumoniae) 		5 / 12 GLU A 189
HIS A 131
LEU A 134
PRO A 187
LEU A 186
 None
 1.27A 5nd4B-3qaxA:
undetectable		 5nd4B-3qaxA:
20.62