SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qay'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		4 / 6 PHE A 119
LYS A 159
LYS A 158
ALA A 157
 None
 1.22A 1hk2A-3qayA:
undetectable		 1hk2A-3qayA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		4 / 8 CYH A   4
LEU A  37
ALA A  34
LEU A  33
 None
 0.92A 1hwiD-3qayA:
undetectable		 1hwiD-3qayA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		4 / 7 PHE A 146
LEU A  33
ASN A  30
ILE A 165
 None
 0.95A 3rfmA-3qayA:
undetectable		 3rfmA-3qayA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		4 / 6 ILE A  81
ILE A 178
ILE A 111
LEU A  79
 None
 0.75A 4o8fB-3qayA:
undetectable		 4o8fB-3qayA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		3 / 3 LYS A   0
HIS A  46
HIS A   0
 None
 1.15A 5oexA-3qayA:
undetectable		 5oexA-3qayA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		3 / 3 LYS A   0
HIS A  46
HIS A   0
 None
 1.17A 5oexB-3qayA:
undetectable		 5oexB-3qayA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		3 / 3 LYS A   0
HIS A  46
HIS A   0
 None
 1.16A 5oexC-3qayA:
undetectable		 5oexC-3qayA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		3 / 3 LYS A   0
HIS A  46
HIS A   0
 None
 1.19A 5oexD-3qayA:
undetectable		 5oexD-3qayA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		5 / 12 LEU A  85
LEU A  33
ILE A 111
LEU A  37
LEU A 142
 None
 0.97A 5toaA-3qayA:
undetectable		 5toaA-3qayA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		3 / 3 GLU A  63
TYR A  67
ARG A  71
 None
 0.80A 5uunA-3qayA:
undetectable		 5uunA-3qayA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3qay ENDOLYSIN
(Clostridium
virus
phiCD27) 		3 / 3 GLU A  63
TYR A  67
ARG A  71
 None
 0.78A 5uunB-3qayA:
undetectable		 5uunB-3qayA:
21.17