SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 3qb5 TRANSLIN-ASSOCIATED
PROTEIN X
(Homo
sapiens) 		4 / 8 GLU K  89
ASP K  82
ILE K  77
THR K  78
 None
 0.87A 1hmyA-3qb5K:
undetectable		 1hmyA-3qb5K:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3qb5 TRANSLIN-ASSOCIATED
PROTEIN X
(Homo
sapiens) 		4 / 5 PRO K 214
GLY K 207
ASN K 208
GLY K 209
 None
 0.94A 1zlqA-3qb5K:
undetectable		 1zlqA-3qb5K:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3qb5 TRANSLIN-ASSOCIATED
PROTEIN X
(Homo
sapiens) 		3 / 3 ASP K 112
THR K 183
PRO K 184
 None
 0.39A 2pynB-3qb5K:
undetectable		 2pynB-3qb5K:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 3qb5 TRANSLIN-ASSOCIATED
PROTEIN X
(Homo
sapiens) 		3 / 3 ASP K 112
THR K 183
PRO K 184
 None
 0.46A 2q64B-3qb5K:
undetectable		 2q64B-3qb5K:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3qb5 TRANSLIN-ASSOCIATED
PROTEIN X
(Homo
sapiens) 		3 / 3 ASP K 112
THR K 183
PRO K 184
 None
 0.40A 2qakB-3qb5K:
undetectable		 2qakB-3qb5K:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3qb5 TRANSLIN-ASSOCIATED
PROTEIN X
(Homo
sapiens) 		3 / 3 LYS K  68
ARG K 200
LYS K 241
 SO4  K 294 ( 2.6A)
SO4  K 293 (-3.4A)
None
 1.36A 3okxA-3qb5K:
undetectable		 3okxA-3qb5K:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 3qb5 TRANSLIN-ASSOCIATED
PROTEIN X
(Homo
sapiens) 		3 / 3 ASP K 112
THR K 183
PRO K 184
 None
 0.50A 3tkgD-3qb5K:
undetectable		 3tkgD-3qb5K:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 3qb5 TRANSLIN-ASSOCIATED
PROTEIN X
(Homo
sapiens) 		3 / 3 GLU K 197
ARG K 200
HIS K  75
 MN  K 291 (-3.3A)
SO4  K 293 (-3.4A)
None
 0.81A 4kf9A-3qb5K:
undetectable		 4kf9A-3qb5K:
22.54