SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qb8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 3qb8 A654L PROTEIN
(Paramecium
bursaria
Chlorella
virus
1) 		4 / 8 ILE A 133
LEU A 129
PHE A 157
GLY A 146
 None
 1.02A 1os6A-3qb8A:
undetectable		 1os6A-3qb8A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2COJ_A_GBNA420_1
(BRANCHED CHAIN
AMINOTRANSFERASE 1,
CYTOSOLIC)		 3qb8 A654L PROTEIN
(Paramecium
bursaria
Chlorella
virus
1) 		5 / 11 PHE A 162
THR A 132
THR A 126
ALA A 125
VAL A 112
 None
None
COA  A 198 (-3.5A)
COA  A 198 (-3.2A)
None
 0.97A 2cojA-3qb8A:
undetectable
2cojB-3qb8A:
undetectable		 2cojA-3qb8A:
19.12
2cojB-3qb8A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3qb8 A654L PROTEIN
(Paramecium
bursaria
Chlorella
virus
1) 		4 / 8 ILE A 133
LEU A 129
PHE A 157
GLY A 146
 None
 0.97A 3selX-3qb8A:
undetectable		 3selX-3qb8A:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 3qb8 A654L PROTEIN
(Paramecium
bursaria
Chlorella
virus
1) 		4 / 7 ILE A 133
LEU A 129
PHE A 157
GLY A 146
 None
 0.92A 4hbfA-3qb8A:
undetectable		 4hbfA-3qb8A:
17.58