SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qbm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZ6_A_CAMA502_0 (CYTOCHROME P450-CAM)	3qbm	TETR TRANSCRIPTIONAL REGULATOR (Chloroflexus aurantiacus)	4 / 5	PHE A 19 TYR A 24 LEU A 119 VAL A 12	None None PGE A 210 ( 4.9A) None	1.42A	1dz6A-3qbmA: undetectable	1dz6A-3qbmA: 19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S45_B_478B201_1 (PROTEASE)	3qbm	TETR TRANSCRIPTIONAL REGULATOR (Chloroflexus aurantiacus)	5 / 9	ASP A 81 GLY A 141 ILE A 142 ILE A 134 ILE A 83	None	0.94A	3s45A-3qbmA: undetectable	3s45A-3qbmA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K6I_A_9RAA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3qbm	TETR TRANSCRIPTIONAL REGULATOR (Chloroflexus aurantiacus)	5 / 12	ILE A 160 LEU A 137 LEU A 87 ALA A 85 VAL A 195	None None None None PEG A 209 ( 4.6A)	1.01A	4k6iA-3qbmA: undetectable	4k6iA-3qbmA: 21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F8C_A_STRA502_1 (CYTOCHROME P450 CYP260A1)	3qbm	TETR TRANSCRIPTIONAL REGULATOR (Chloroflexus aurantiacus)	4 / 6	ALA A 61 GLY A 23 THR A 27 ILE A 32	None	0.82A	6f8cA-3qbmA: undetectable	6f8cA-3qbmA: 21.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DZ6_A_CAMA502_0","CYTOCHROME P450-CAM","3qbm","TETR TRANSCRIPTIONAL REGULATOR","Chloroflexus aurantiacus",4,"PHE A  19;TYR A  24;LEU A 119;VAL A  12","None;None;PGE A 210 ( 4.9A);None","1.42A","1dz6A-3qbmA:undetectable","1dz6A-3qbmA:19.71"],["3S45_B_478B201_1","PROTEASE;PROTEASE","3qbm","TETR TRANSCRIPTIONAL REGULATOR","Chloroflexus aurantiacus",5,"ASP A  81;GLY A 141;ILE A 142;ILE A 134;ILE A  83","None","0.94A","3s45A-3qbmA:undetectable","3s45A-3qbmA:19.70"],["4K6I_A_9RAA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3qbm","TETR TRANSCRIPTIONAL REGULATOR","Chloroflexus aurantiacus",5,"ILE A 160;LEU A 137;LEU A  87;ALA A  85;VAL A 195","None;None;None;None;PEG A 209 ( 4.6A)","1.01A","4k6iA-3qbmA:undetectable","4k6iA-3qbmA:21.16"],["6F8C_A_STRA502_1","CYTOCHROME P450 CYP260A1","3qbm","TETR TRANSCRIPTIONAL REGULATOR","Chloroflexus aurantiacus",4,"ALA A  61;GLY A  23;THR A  27;ILE A  32","None","0.82A","6f8cA-3qbmA:undetectable","6f8cA-3qbmA:21.71"]]