SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qc0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 219
HIS A 144
TYR A 147
LEU A 215
HIS A 179
 None
None
UNL  A 300 ( 4.2A)
UNL  A 300 ( 4.5A)
UNL  A 300 ( 4.1A)
 1.30A 1zgyA-3qc0A:
undetectable		 1zgyA-3qc0A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		4 / 5 LEU A   6
ILE A   8
ILE A 263
ALA A 264
 None
 0.76A 2i2zA-3qc0A:
undetectable		 2i2zA-3qc0A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 219
HIS A 144
TYR A 147
LEU A 215
HIS A 179
 None
None
UNL  A 300 ( 4.2A)
UNL  A 300 ( 4.5A)
UNL  A 300 ( 4.1A)
 1.42A 2prgA-3qc0A:
0.0		 2prgA-3qc0A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 11 LEU A 186
LEU A 157
LEU A 161
ARG A 234
ILE A 231
 None
 1.28A 2qd3A-3qc0A:
undetectable		 2qd3A-3qc0A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		4 / 9 ILE A 248
ALA A 259
VAL A 262
CYH A 266
 None
 1.02A 2vufB-3qc0A:
undetectable		 2vufB-3qc0A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		4 / 5 ILE A   8
MET A 221
ILE A 204
HIS A 203
 None
None
None
ZN  A 301 (-3.3A)
 1.24A 3eteB-3qc0A:
undetectable
3eteC-3qc0A:
undetectable		 3eteB-3qc0A:
19.35
3eteC-3qc0A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 12 LEU A 167
GLY A 168
ILE A 124
ALA A 131
LEU A 101
 None
 0.89A 3gwvA-3qc0A:
undetectable		 3gwvA-3qc0A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		6 / 10 THR A 166
GLY A 168
GLU A 165
LEU A 167
LEU A 128
ILE A 124
 None
 1.35A 3kvrB-3qc0A:
undetectable		 3kvrB-3qc0A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 9 THR A 166
GLU A 165
LEU A 167
LEU A 128
ILE A 124
 None
 1.31A 3nbqA-3qc0A:
undetectable		 3nbqA-3qc0A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 9 THR A 166
GLY A 168
GLU A 165
LEU A 167
ILE A 124
 None
 1.27A 3nbqA-3qc0A:
undetectable		 3nbqA-3qc0A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 9 GLY A  66
ILE A 140
GLY A 123
ILE A  81
LEU A 138
 None
 0.98A 3ogpA-3qc0A:
undetectable		 3ogpA-3qc0A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 10 LEU A  99
VAL A 171
ILE A  81
VAL A 136
LEU A 138
 None
 1.06A 3ogpB-3qc0A:
undetectable		 3ogpB-3qc0A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 10 SER A   7
LEU A  94
VAL A  41
PHE A  19
VAL A  53
 None
 1.30A 3u9fE-3qc0A:
undetectable		 3u9fE-3qc0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 10 SER A   7
LEU A  94
VAL A  41
PHE A  19
VAL A  53
 None
 1.34A 3u9fI-3qc0A:
undetectable		 3u9fI-3qc0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 12 SER A   7
LEU A  94
VAL A  41
PHE A  19
VAL A  53
 None
 1.33A 3u9fJ-3qc0A:
undetectable
3u9fK-3qc0A:
undetectable		 3u9fJ-3qc0A:
19.86
3u9fK-3qc0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 12 SER A   7
LEU A  94
VAL A  41
PHE A  19
VAL A  53
 None
 1.38A 3u9fP-3qc0A:
undetectable
3u9fS-3qc0A:
undetectable		 3u9fP-3qc0A:
19.86
3u9fS-3qc0A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 11 ILE A 226
ASP A 227
ILE A 231
GLY A 230
SER A   7
 None
 0.99A 4ac9B-3qc0A:
2.8
4ac9C-3qc0A:
2.4		 4ac9B-3qc0A:
20.61
4ac9C-3qc0A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 219
HIS A 144
TYR A 147
LEU A 215
HIS A 179
 None
None
UNL  A 300 ( 4.2A)
UNL  A 300 ( 4.5A)
UNL  A 300 ( 4.1A)
 1.47A 4emaA-3qc0A:
undetectable		 4emaA-3qc0A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 219
HIS A 144
TYR A 147
LEU A 215
HIS A 179
 None
None
UNL  A 300 ( 4.2A)
UNL  A 300 ( 4.5A)
UNL  A 300 ( 4.1A)
 1.38A 4xldA-3qc0A:
undetectable		 4xldA-3qc0A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JI0_D_BRLD501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A 219
HIS A 144
TYR A 147
LEU A 215
HIS A 179
 None
None
UNL  A 300 ( 4.2A)
UNL  A 300 ( 4.5A)
UNL  A 300 ( 4.1A)
 1.33A 5ji0D-3qc0A:
undetectable		 5ji0D-3qc0A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3qc0 SUGAR ISOMERASE
(Sinorhizobium
meliloti) 		5 / 12 GLY A  66
VAL A 171
GLY A 123
ILE A  81
PRO A 129
 None
 0.92A 5t2zA-3qc0A:
undetectable		 5t2zA-3qc0A:
16.79