SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qc2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 5 HIS A 232
GLU A 231
SER A 267
HIS A 292
 None
 1.31A 1errA-3qc2A:
undetectable
1errB-3qc2A:
undetectable		 1errA-3qc2A:
20.44
1errB-3qc2A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		5 / 12 GLY A 289
VAL A 233
LEU A 285
ALA A 310
PHE A 258
 None
 1.09A 1gseB-3qc2A:
undetectable		 1gseB-3qc2A:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 8 GLU A 349
GLY A 273
ASP A 366
THR A 345
 None
 0.90A 1m4iA-3qc2A:
undetectable		 1m4iA-3qc2A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		3 / 3 TYR A 300
GLY A 296
PHE A 265
 None
 0.69A 2m2pB-3qc2A:
undetectable		 2m2pB-3qc2A:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		3 / 3 GLY A 263
ASP A 297
SER A 267
 None
 0.62A 2qhfA-3qc2A:
undetectable		 2qhfA-3qc2A:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 5 ALA A 187
GLY A 200
CYH A 201
LYS A 202
 None
 1.38A 2ylgA-3qc2A:
undetectable		 2ylgA-3qc2A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 7 THR A 182
VAL A 172
THR A 174
VAL A 157
 None
 0.60A 3em0B-3qc2A:
undetectable		 3em0B-3qc2A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_2
(ALPHA-GLUCOSIDASE)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 5 PRO A 274
ILE A 348
TYR A 227
TRP A 244
 None
 1.48A 3phaA-3qc2A:
undetectable		 3phaA-3qc2A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		3 / 3 THR A  57
ASN A  56
GLU A  71
 None
 0.79A 3v4tA-3qc2A:
undetectable
3v4tC-3qc2A:
undetectable		 3v4tA-3qc2A:
23.52
3v4tC-3qc2A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 8 ILE A 348
TRP A  36
GLY A  40
ASN A  31
 None
 0.99A 4fgjA-3qc2A:
undetectable
4fgjB-3qc2A:
undetectable		 4fgjA-3qc2A:
23.55
4fgjB-3qc2A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 8 GLY A 370
ASN A  48
PRO A  78
ILE A  51
 None
 0.95A 4j4vC-3qc2A:
undetectable		 4j4vC-3qc2A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 7 PHE A 192
THR A 237
VAL A 248
PHE A 234
 None
 0.96A 4wnvD-3qc2A:
undetectable		 4wnvD-3qc2A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 7 GLU A 271
ARG A 147
TYR A 305
GLU A 349
 None
 1.08A 4zz8A-3qc2A:
undetectable		 4zz8A-3qc2A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 6 SER A  72
GLU A  55
GLY A 102
GLY A 100
 None
 0.70A 5cdpA-3qc2A:
undetectable
5cdpB-3qc2A:
undetectable		 5cdpA-3qc2A:
23.12
5cdpB-3qc2A:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		3 / 3 VAL A  88
SER A 175
MET A 159
 None
 0.79A 5ikqA-3qc2A:
undetectable		 5ikqA-3qc2A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 5 ALA A 187
GLY A 200
CYH A 201
LYS A 202
 None
 1.41A 5jliA-3qc2A:
undetectable		 5jliA-3qc2A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 5 ALA A 187
GLY A 200
CYH A 201
LYS A 202
 None
 1.47A 5jt4A-3qc2A:
undetectable		 5jt4A-3qc2A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_1
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		3 / 3 SER A 203
SER A 205
PHE A 347
 None
 0.93A 5mugA-3qc2A:
undetectable		 5mugA-3qc2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 8 ARG A 319
THR A 318
PRO A 317
ILE A 247
 None
 0.97A 6a4iA-3qc2A:
undetectable		 6a4iA-3qc2A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 5 PHE A 119
VAL A 126
PRO A  78
VAL A  50
 None
 1.30A 6ekzA-3qc2A:
undetectable		 6ekzA-3qc2A:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 3qc2 GLYCOSYL HYDROLASE
(Bacteroides
ovatus) 		4 / 4 LEU A 108
ASP A 145
PRO A 146
ARG A  92
 None
 1.08A 6fgdA-3qc2A:
undetectable		 6fgdA-3qc2A:
23.56