SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 3qc3 D-RIBULOSE-5-PHOSPHA
TE-3-EPIMERASE
(Homo
sapiens) 		4 / 6 SER A 196
VAL A 178
GLY A 179
GLU A 188
 None
 0.94A 1fduD-3qc3A:
undetectable		 1fduD-3qc3A:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 3qc3 D-RIBULOSE-5-PHOSPHA
TE-3-EPIMERASE
(Homo
sapiens) 		4 / 6 PRO A 168
PHE A 167
GLN A 166
VAL A 160
 None
 1.46A 1l2iB-3qc3A:
undetectable		 1l2iB-3qc3A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 3qc3 D-RIBULOSE-5-PHOSPHA
TE-3-EPIMERASE
(Homo
sapiens) 		3 / 3 HIS A  70
HIS A  94
MET A  72
 FE  A 231 ( 3.0A)
None
GOL  A 232 (-4.0A)
 0.66A 3mihA-3qc3A:
undetectable		 3mihA-3qc3A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3qc3 D-RIBULOSE-5-PHOSPHA
TE-3-EPIMERASE
(Homo
sapiens) 		3 / 3 HIS A  51
SER A  56
GLU A  55
 None
 0.73A 3s8pA-3qc3A:
undetectable		 3s8pA-3qc3A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 3qc3 D-RIBULOSE-5-PHOSPHA
TE-3-EPIMERASE
(Homo
sapiens) 		3 / 3 CYH A 186
LYS A 185
HIS A 184
 None
 1.04A 5js5A-3qc3A:
undetectable		 5js5A-3qc3A:
21.88