SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qc5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		3 / 3 TRP X 386
ALA X 295
VAL X 360
 None
 0.83A 1c4dC-3qc5X:
undetectable
1c4dD-3qc5X:
undetectable		 1c4dC-3qc5X:
5.71
1c4dD-3qc5X:
5.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 LEU X 373
THR X 382
GLN X 288
MET X 263
 None
 1.08A 1kglA-3qc5X:
2.1		 1kglA-3qc5X:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 LYS X 466
LEU X 465
GLN X 464
LEU X 434
 None
None
None
NA  X 609 (-4.7A)
 1.02A 1v55C-3qc5X:
undetectable
1v55J-3qc5X:
undetectable		 1v55C-3qc5X:
19.45
1v55J-3qc5X:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 LYS X 466
LEU X 465
GLN X 464
LEU X 434
 None
None
None
NA  X 609 (-4.7A)
 1.05A 1v55P-3qc5X:
undetectable
1v55W-3qc5X:
undetectable		 1v55P-3qc5X:
19.45
1v55W-3qc5X:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 LYS X 466
LEU X 465
GLN X 464
LEU X 434
 None
None
None
NA  X 609 (-4.7A)
 1.00A 2dysP-3qc5X:
undetectable
2dysW-3qc5X:
undetectable		 2dysP-3qc5X:
19.45
2dysW-3qc5X:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 LYS X 466
LEU X 465
GLN X 464
LEU X 434
 None
None
None
NA  X 609 (-4.7A)
 1.05A 2eijC-3qc5X:
undetectable
2eijJ-3qc5X:
undetectable		 2eijC-3qc5X:
19.45
2eijJ-3qc5X:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 LYS X 466
LEU X 465
GLN X 464
LEU X 434
 None
None
None
NA  X 609 (-4.7A)
 1.03A 2eijP-3qc5X:
undetectable
2eijW-3qc5X:
undetectable		 2eijP-3qc5X:
19.45
2eijW-3qc5X:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 LYS X 466
LEU X 465
GLN X 464
LEU X 434
 None
None
None
NA  X 609 (-4.7A)
 1.02A 2eimC-3qc5X:
undetectable
2eimJ-3qc5X:
undetectable		 2eimC-3qc5X:
19.45
2eimJ-3qc5X:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 LYS X 466
LEU X 465
GLN X 464
LEU X 434
 None
None
None
NA  X 609 (-4.7A)
 0.91A 2einC-3qc5X:
undetectable
2einJ-3qc5X:
undetectable		 2einC-3qc5X:
19.45
2einJ-3qc5X:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		5 / 12 GLY X 390
ALA X 389
ASP X 258
VAL X 297
ILE X 264
 None
 0.70A 2f8gB-3qc5X:
undetectable		 2f8gB-3qc5X:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 TYR X 256
VAL X 254
TYR X 391
ILE X 264
 None
 1.06A 2x45B-3qc5X:
undetectable		 2x45B-3qc5X:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 TYR X 256
VAL X 254
TYR X 391
ILE X 264
 None
 1.07A 2x45C-3qc5X:
undetectable		 2x45C-3qc5X:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 LYS X 466
LEU X 465
GLN X 464
LEU X 434
 None
None
None
NA  X 609 (-4.7A)
 0.99A 2zxwC-3qc5X:
undetectable
2zxwJ-3qc5X:
undetectable		 2zxwC-3qc5X:
19.45
2zxwJ-3qc5X:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BU1_A_HSMA301_1
(LIPOCALIN)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 7 TYR X 256
VAL X 254
TYR X 391
ILE X 264
 None
 1.08A 3bu1A-3qc5X:
undetectable		 3bu1A-3qc5X:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		5 / 12 GLY X 390
ALA X 389
ASP X 258
VAL X 297
ILE X 264
 None
 0.77A 3nu5A-3qc5X:
undetectable		 3nu5A-3qc5X:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		5 / 9 GLY X 390
ALA X 389
ASP X 258
VAL X 297
ILE X 264
 None
 0.97A 3oxvA-3qc5X:
undetectable		 3oxvA-3qc5X:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		3 / 3 ASP X 399
ASP X 427
ASN X 496
 K  X   1 (-2.1A)
K  X   1 ( 2.0A)
None
 0.82A 4q5mA-3qc5X:
undetectable		 4q5mA-3qc5X:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 6 LEU X 373
LEU X 329
THR X 382
VAL X 378
 None
 1.00A 4udaA-3qc5X:
undetectable		 4udaA-3qc5X:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 6 LEU X 373
THR X 382
GLN X 288
MET X 263
 None
 1.08A 5h8tA-3qc5X:
1.0		 5h8tA-3qc5X:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		4 / 8 LEU X 373
THR X 382
GLN X 288
MET X 263
 None
 1.07A 5hbsA-3qc5X:
undetectable		 5hbsA-3qc5X:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		5 / 12 GLY X 301
ASN X 347
SER X 298
TRP X 280
GLY X 351
 None
GOL  X 606 (-3.7A)
None
None
None
 0.99A 5hikA-3qc5X:
undetectable		 5hikA-3qc5X:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 3qc5 PLATELET BINDING
PROTEIN GSPB
(Streptococcus
gordonii) 		5 / 12 TYR X 391
ILE X 264
ARG X 358
LEU X 359
HIS X 257
 None
 1.44A 5zwrB-3qc5X:
undetectable		 5zwrB-3qc5X:
20.19