SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qd5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVX_B_DIFB125_2
(TRANSTHYRETIN)		 3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE
(Coccidioides
immitis) 		4 / 7 ALA A  12
SER A  38
THR A  40
VAL A  42
 None
 1.02A 1dvxB-3qd5A:
undetectable		 1dvxB-3qd5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE
(Coccidioides
immitis) 		4 / 7 VAL A  82
GLY A  81
THR A  78
ASP A  17
 CSO  A  76 ( 3.8A)
CSO  A  76 (-3.4A)
CSO  A  76 (-3.8A)
None
 0.95A 2a1mA-3qd5A:
undetectable		 2a1mA-3qd5A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE
(Coccidioides
immitis) 		4 / 6 ALA A  12
SER A  38
THR A  40
VAL A  42
 None
 1.07A 3d2tB-3qd5A:
undetectable		 3d2tB-3qd5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE
(Coccidioides
immitis) 		5 / 9 MET A  74
ALA A  12
SER A  38
THR A  40
VAL A  42
 None
 0.97A 3ozkA-3qd5A:
undetectable		 3ozkA-3qd5A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_B_T44B128_1
(TRANSTHYRETIN)		 3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE
(Coccidioides
immitis) 		4 / 7 ALA A  12
SER A  38
THR A  40
VAL A  42
 None
 0.80A 3ozkB-3qd5A:
undetectable		 3ozkB-3qd5A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE
(Coccidioides
immitis) 		5 / 10 GLY A 118
ALA A  18
GLY A  77
VAL A  82
CYH A  15
 CSO  A  76 ( 3.4A)
IOD  A 171 ( 4.3A)
CSO  A  76 (-2.3A)
CSO  A  76 ( 3.8A)
None
 1.39A 4c5nD-3qd5A:
3.2		 4c5nD-3qd5A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE
(Coccidioides
immitis) 		4 / 7 MET A  74
ALA A  12
THR A  40
VAL A  42
 None
 0.91A 4ik7A-3qd5A:
undetectable		 4ik7A-3qd5A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE
(Coccidioides
immitis) 		5 / 11 PRO A  54
VAL A  56
ALA A  57
GLY A  81
THR A  51
 IOD  A 174 ( 4.4A)
None
None
CSO  A  76 (-3.4A)
None
 1.21A 4mmaA-3qd5A:
undetectable		 4mmaA-3qd5A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW5_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3qd5 PUTATIVE
RIBOSE-5-PHOSPHATE
ISOMERASE
(Coccidioides
immitis) 		4 / 8 GLY A 118
GLY A  79
LEU A  80
ALA A  83
 CSO  A  76 ( 3.4A)
CSO  A  76 ( 3.4A)
None
None
 0.72A 5vw5A-3qd5A:
undetectable		 5vw5A-3qd5A:
19.87