SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qd7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qd7 UNCHARACTERIZED
PROTEIN YDAL
(Escherichia
coli) 		3 / 3 ASN X 132
HIS X 130
VAL X  95
 None
 0.90A 3elzB-3qd7X:
undetectable		 3elzB-3qd7X:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3qd7 UNCHARACTERIZED
PROTEIN YDAL
(Escherichia
coli) 		5 / 12 VAL X 138
LEU X 142
ILE X 120
GLY X 162
ALA X 163
 None
 1.08A 3kk6A-3qd7X:
undetectable		 3kk6A-3qd7X:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3qd7 UNCHARACTERIZED
PROTEIN YDAL
(Escherichia
coli) 		5 / 9 VAL X 138
PHE X 105
ILE X 119
VAL X 148
VAL X 166
 None
 1.18A 3me6C-3qd7X:
undetectable		 3me6C-3qd7X:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 3qd7 UNCHARACTERIZED
PROTEIN YDAL
(Escherichia
coli) 		5 / 9 VAL X 138
PHE X 105
ILE X 119
VAL X 148
VAL X 166
 None
 1.22A 3me6D-3qd7X:
undetectable		 3me6D-3qd7X:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIK_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 3qd7 UNCHARACTERIZED
PROTEIN YDAL
(Escherichia
coli) 		5 / 12 ARG X  92
GLY X 122
ASN X  89
GLY X 160
SER X 161
 None
 1.26A 5hikA-3qd7X:
3.7		 5hikA-3qd7X:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3qd7 UNCHARACTERIZED
PROTEIN YDAL
(Escherichia
coli) 		4 / 6 VAL X 117
LEU X 168
CYH X 164
LEU X 142
 None
 0.91A 5hrqB-3qd7X:
undetectable
5hrqI-3qd7X:
undetectable
5hrqJ-3qd7X:
undetectable		 5hrqB-3qd7X:
22.06
5hrqI-3qd7X:
10.68
5hrqJ-3qd7X:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3qd7 UNCHARACTERIZED
PROTEIN YDAL
(Escherichia
coli) 		4 / 6 VAL X 138
LEU X 142
CYH X  98
LEU X  88
 None
 1.09A 5hrqB-3qd7X:
undetectable
5hrqI-3qd7X:
undetectable
5hrqJ-3qd7X:
undetectable		 5hrqB-3qd7X:
22.06
5hrqI-3qd7X:
10.68
5hrqJ-3qd7X:
22.06