SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qd8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		4 / 7 HIS A  12
ASN A  21
LEU A 109
GLN A  18
 None
 1.12A 1qzrA-3qd8A:
undetectable		 1qzrA-3qd8A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		4 / 7 HIS A  12
ASN A  21
LEU A 109
GLN A  18
 None
 1.13A 1qzrB-3qd8A:
undetectable		 1qzrB-3qd8A:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		4 / 8 SER A  50
PHE A  48
ALA A  95
LEU A  92
 None
 1.07A 2bxkA-3qd8A:
2.7		 2bxkA-3qd8A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		4 / 8 PHE A  36
ARG A  89
ALA A  93
LEU A  92
 None
 1.09A 2o01A-3qd8A:
undetectable		 2o01A-3qd8A:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		4 / 7 PHE A  48
TYR A  29
VAL A 136
VAL A 143
 None
 0.90A 2qbnA-3qd8A:
undetectable		 2qbnA-3qd8A:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		4 / 5 ALA A 167
GLU A 131
GLU A  54
ALA A 170
 None
 1.36A 3r9tC-3qd8A:
undetectable		 3r9tC-3qd8A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		4 / 7 TYR A  29
GLU A  54
GLU A  99
GLU A  22
 None
 1.25A 4mi4A-3qd8A:
undetectable
4mi4C-3qd8A:
undetectable		 4mi4A-3qd8A:
19.63
4mi4C-3qd8A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		5 / 12 MET A  15
LEU A  71
ALA A 113
ASP A 118
LEU A 120
 None
 1.37A 4qdcA-3qd8A:
undetectable		 4qdcA-3qd8A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		4 / 7 ASN A  57
GLU A  22
GLU A  54
GLU A 135
 None
 1.22A 4r87I-3qd8A:
undetectable		 4r87I-3qd8A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3qd8 PROBABLE
BACTERIOFERRITIN
BFRB
(Mycobacterium
tuberculosis) 		4 / 6 GLN A  98
VAL A 102
GLU A 131
ALA A 167
 None
 1.24A 6djzB-3qd8A:
undetectable		 6djzB-3qd8A:
21.72