SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qd9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		4 / 7 LEU A 250
LEU A 245
MET A 227
MET A 319
 None
 0.99A 1kt3A-3qd9A:
undetectable		 1kt3A-3qd9A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		3 / 3 LEU A  95
HIS A 184
ILE A 181
 None
 0.66A 1s9pB-3qd9A:
undetectable		 1s9pB-3qd9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_B_SALB503_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		5 / 10 ALA A 222
PHE A 248
TYR A 343
PHE A 315
LEU A 323
 None
 1.40A 1y7iB-3qd9A:
undetectable		 1y7iB-3qd9A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		4 / 8 SER A 353
PHE A 357
ALA A 375
LEU A 372
 FAD  A 501 (-3.4A)
FAD  A 501 (-3.7A)
None
None
 1.07A 2bxkA-3qd9A:
1.5		 2bxkA-3qd9A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		4 / 5 ILE A 259
PHE A 248
VAL A 379
PHE A 315
 None
 1.25A 2ygnA-3qd9A:
undetectable		 2ygnA-3qd9A:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		4 / 8 ASP A  37
PHE A  79
LEU A  43
ASP A  42
 None
 0.94A 3m0wE-3qd9A:
1.9
3m0wF-3qd9A:
1.0
3m0wG-3qd9A:
1.9
3m0wH-3qd9A:
1.8		 3m0wE-3qd9A:
13.23
3m0wF-3qd9A:
13.23
3m0wG-3qd9A:
13.23
3m0wH-3qd9A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_D_ACTD1113_0
(BLR5658 PROTEIN)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		4 / 4 TRP A 282
LEU A 268
LEU A 242
THR A 236
 None
 1.42A 4bboD-3qd9A:
undetectable		 4bboD-3qd9A:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA8_C_Z80C301_1
(MAJOR PRION PROTEIN)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		4 / 5 LEU A  86
GLY A  85
ILE A 181
LYS A 177
 None
 1.17A 4ma8C-3qd9A:
undetectable		 4ma8C-3qd9A:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		5 / 10 LEU A 268
LEU A 245
VAL A 252
LEU A 326
LEU A 322
 None
 1.12A 4po0A-3qd9A:
undetectable		 4po0A-3qd9A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		5 / 8 LEU A  86
ALA A 100
LEU A 158
LEU A  95
ALA A  98
 None
 1.06A 4z90A-3qd9A:
2.4
4z90B-3qd9A:
2.1
4z90C-3qd9A:
undetectable
4z90D-3qd9A:
undetectable
4z90E-3qd9A:
undetectable		 4z90A-3qd9A:
21.16
4z90B-3qd9A:
21.16
4z90C-3qd9A:
21.16
4z90D-3qd9A:
21.16
4z90E-3qd9A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		5 / 9 THR A  78
ALA A  76
GLY A  84
ALA A  83
ASP A  37
 None
 1.09A 5d0xK-3qd9A:
undetectable
5d0xL-3qd9A:
undetectable		 5d0xK-3qd9A:
18.99
5d0xL-3qd9A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		5 / 9 THR A  78
ALA A  76
GLY A  84
ALA A  83
ASP A  37
 None
 1.08A 5d0xY-3qd9A:
undetectable
5d0xZ-3qd9A:
undetectable		 5d0xY-3qd9A:
18.99
5d0xZ-3qd9A:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		5 / 12 LEU A 233
SER A 232
GLN A 283
ILE A 117
VAL A 120
 None
 1.13A 5dpdA-3qd9A:
undetectable		 5dpdA-3qd9A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		4 / 8 LEU A 337
LEU A 251
HIS A 324
LEU A 323
 None
None
FAD  A 501 (-3.4A)
None
 1.26A 5dxeA-3qd9A:
undetectable		 5dxeA-3qd9A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3qd9 QSOX FROM
TRYPANOSOMA BRUCEI
(TBQSOX)
(Trypanosoma
brucei) 		4 / 8 LEU A 337
LEU A 251
HIS A 324
LEU A 323
 None
None
FAD  A 501 (-3.4A)
None
 1.28A 6cbzA-3qd9A:
undetectable		 6cbzA-3qd9A:
10.55