SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qdk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 5 TYR A 177
PRO A 101
LEU A 184
THR A 235
 None
 1.26A 1i2wA-3qdkA:
undetectable		 1i2wA-3qdkA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMK_A_H4BA1427_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 12 VAL A 284
LEU A 302
LEU A 303
HIS A 441
GLU A 439
 None
 1.39A 1mmkA-3qdkA:
undetectable		 1mmkA-3qdkA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		3 / 3 GLU A 439
HIS A 434
HIS A 441
 None
 0.71A 1oe2A-3qdkA:
undetectable		 1oe2A-3qdkA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 12 GLY A   9
GLY A  91
GLY A  89
GLN A 475
ASP A  11
 None
 1.14A 1wg8A-3qdkA:
undetectable		 1wg8A-3qdkA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 12 GLY A   9
GLY A  91
GLY A  89
GLN A 475
ASP A  11
 None
 1.12A 1wg8B-3qdkA:
undetectable		 1wg8B-3qdkA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 5 VAL A  92
ASN A 272
VAL A 191
ILE A  90
 None
 1.06A 1z2bC-3qdkA:
undetectable		 1z2bC-3qdkA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 11 GLY A 206
TYR A 207
GLU A 307
TYR A 153
GLU A 215
 None
 1.25A 2fl5A-3qdkA:
undetectable
2fl5B-3qdkA:
2.1
2fl5F-3qdkA:
2.2		 2fl5A-3qdkA:
16.61
2fl5B-3qdkA:
16.84
2fl5F-3qdkA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 7 ILE A 298
THR A 426
MET A 457
LEU A 443
 None
 0.86A 2xrhA-3qdkA:
undetectable		 2xrhA-3qdkA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 5 ILE A 392
HIS A 535
ARG A 427
GLY A 425
 None
 1.28A 3b9mA-3qdkA:
undetectable		 3b9mA-3qdkA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 9 LEU A 456
ILE A 468
ALA A 445
ALA A 423
THR A 426
 None
 1.15A 3mdvA-3qdkA:
undetectable		 3mdvA-3qdkA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 12 GLY A 106
ALA A 186
GLU A 185
LEU A 111
LEU A 100
 None
 1.10A 3p2kB-3qdkA:
undetectable		 3p2kB-3qdkA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_E_PFLE319_1
(GLR4197 PROTEIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 7 ILE A 266
LEU A 252
THR A   7
ILE A   8
 None
 0.98A 3p50E-3qdkA:
undetectable		 3p50E-3qdkA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 12 LEU A 393
ASP A 384
GLY A 425
ALA A 428
ALA A 432
 None
 0.59A 3p5nA-3qdkA:
undetectable		 3p5nA-3qdkA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 12 LEU A 393
ASP A 384
GLY A 425
ALA A 428
ALA A 432
 None
 0.59A 3p5nB-3qdkA:
undetectable		 3p5nB-3qdkA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 5 PHE A 433
ILE A 429
GLY A 312
CYH A 314
 None
 0.97A 3r0lD-3qdkA:
undetectable		 3r0lD-3qdkA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 4 LEU A 380
GLY A 379
GLY A 404
THR A 406
 None
 0.84A 3si7A-3qdkA:
undetectable		 3si7A-3qdkA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 5 LEU A 380
GLY A 379
GLY A 404
THR A 406
 None
 0.80A 3si7C-3qdkA:
undetectable
3si7D-3qdkA:
undetectable		 3si7C-3qdkA:
20.55
3si7D-3qdkA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 7 SER A 391
GLY A 425
THR A 426
ILE A 429
 None
 0.67A 4acaC-3qdkA:
undetectable		 4acaC-3qdkA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIM_A_CELA711_1
(LACTOTRANSFERRIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 9 GLU A 439
GLY A 288
GLU A 318
TYR A 325
GLY A 327
 None
 1.10A 4fimA-3qdkA:
undetectable		 4fimA-3qdkA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 4 HIS A  55
GLU A 172
HIS A 120
LEU A  46
 None
 1.46A 4m2rA-3qdkA:
undetectable		 4m2rA-3qdkA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 10 LEU A 455
ILE A 459
LEU A 419
TYR A 524
LEU A 527
 None
 1.03A 4odoA-3qdkA:
undetectable		 4odoA-3qdkA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 10 LEU A 455
ILE A 459
LEU A 419
TYR A 524
LEU A 527
 None
 1.03A 4odoB-3qdkA:
undetectable		 4odoB-3qdkA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUC_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 4 SER A 202
GLU A 247
SER A 498
ASP A 319
 None
 1.18A 4xucA-3qdkA:
0.5		 4xucA-3qdkA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EQB_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 12 GLY A 379
ILE A 298
PHE A 339
GLY A 295
PHE A 424
 None
 1.07A 5eqbA-3qdkA:
undetectable		 5eqbA-3qdkA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 7 TYR A 528
VAL A 463
ILE A 459
ALA A 423
 None
 0.76A 5osrA-3qdkA:
undetectable		 5osrA-3qdkA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		4 / 6 GLU A  56
TRP A  57
HIS A 128
ALA A  58
 None
 1.10A 6f6jC-3qdkA:
undetectable
6f6jD-3qdkA:
undetectable		 6f6jC-3qdkA:
23.47
6f6jD-3qdkA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		3 / 3 THR A 285
ALA A 503
LYS A 505
 None
 0.70A 6fgcA-3qdkA:
undetectable		 6fgcA-3qdkA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		5 / 11 PHE A 460
ILE A 459
LEU A 456
LEU A 443
ILE A 429
 None
 1.08A 6fgcA-3qdkA:
undetectable		 6fgcA-3qdkA:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 3qdk RIBULOKINASE
(Bacillus
halodurans) 		3 / 3 THR A 285
ALA A 503
LYS A 505
 None
 0.74A 6fgdA-3qdkA:
undetectable		 6fgdA-3qdkA:
22.80