SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qdl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3qdl OXYGEN-INSENSITIVE
NADPH NITROREDUCTASE
(Helicobacter
pylori) 		5 / 10 ALA A  80
LEU A  33
LEU A 188
LEU A 156
ILE A  36
 None
 1.15A 3wdmB-3qdlA:
undetectable		 3wdmB-3qdlA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3qdl OXYGEN-INSENSITIVE
NADPH NITROREDUCTASE
(Helicobacter
pylori) 		5 / 10 ALA A  80
LEU A  33
LEU A 188
LEU A 156
ILE A  36
 None
 1.14A 3wdmD-3qdlA:
undetectable		 3wdmD-3qdlA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3qdl OXYGEN-INSENSITIVE
NADPH NITROREDUCTASE
(Helicobacter
pylori) 		5 / 10 ILE A 186
ALA A  40
CYH A 140
ALA A 143
ILE A 147
 None
 1.04A 4lbgA-3qdlA:
undetectable		 4lbgA-3qdlA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3qdl OXYGEN-INSENSITIVE
NADPH NITROREDUCTASE
(Helicobacter
pylori) 		5 / 12 PHE A  54
MET A  84
ILE A 186
ALA A  40
TYR A 141
 None
 1.22A 4qynA-3qdlA:
undetectable		 4qynA-3qdlA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 3qdl OXYGEN-INSENSITIVE
NADPH NITROREDUCTASE
(Helicobacter
pylori) 		4 / 4 PHE A 164
LEU A  62
LEU A  83
VAL A 172
 None
 1.35A 5xxiA-3qdlA:
undetectable		 5xxiA-3qdlA:
18.00