SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qdm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3qdm DMF4 BETA CHAIN
(Homo
sapiens) 		4 / 8 THR E 108
THR E  13
LEU E  21
VAL E  19
 None
 0.92A 1t86A-3qdmE:
undetectable		 1t86A-3qdmE:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3qdm DMF4 BETA CHAIN
(Homo
sapiens) 		4 / 8 TYR E  64
THR E  20
TYR E  89
TRP E  34
 None
 1.26A 3wipC-3qdmE:
undetectable
3wipD-3qdmE:
undetectable		 3wipC-3qdmE:
21.51
3wipD-3qdmE:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3qdm DMF4 BETA CHAIN
(Homo
sapiens) 		4 / 8 TRP E  34
TYR E  64
THR E  20
TYR E  89
 None
 1.32A 3wipA-3qdmE:
undetectable
3wipE-3qdmE:
undetectable		 3wipA-3qdmE:
21.51
3wipE-3qdmE:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3qdm DMF4 BETA CHAIN
(Homo
sapiens) 		4 / 6 TYR E 150
LEU E 113
VAL E  12
ASP E 152
 None
 1.10A 4ek1A-3qdmE:
undetectable		 4ek1A-3qdmE:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4A_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3qdm DMF4 BETA CHAIN
(Homo
sapiens) 		4 / 8 THR E 108
THR E  13
LEU E  21
VAL E  19
 None
 0.89A 4l4aA-3qdmE:
undetectable		 4l4aA-3qdmE:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3qdm DMF4 BETA CHAIN
(Homo
sapiens) 		4 / 6 TYR E 150
LEU E 113
VAL E  12
ASP E 152
 None
 1.11A 4l4cA-3qdmE:
undetectable		 4l4cA-3qdmE:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3qdm DMF4 BETA CHAIN
(Homo
sapiens) 		4 / 8 THR E 108
THR E  13
LEU E  21
VAL E  19
 None
 0.87A 4l4dA-3qdmE:
undetectable		 4l4dA-3qdmE:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3qdm DMF4 BETA CHAIN
(Homo
sapiens) 		4 / 8 THR E 108
THR E  13
LEU E  21
VAL E  19
 None
 0.92A 4l4eA-3qdmE:
undetectable		 4l4eA-3qdmE:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3qdm DMF4 BETA CHAIN
(Homo
sapiens) 		4 / 8 THR E 108
THR E  13
LEU E  21
VAL E  19
 None
 0.91A 4l4fA-3qdmE:
undetectable		 4l4fA-3qdmE:
20.14