SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qdr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 3qdr PROTEIN TOLA
(Escherichia
coli) 		5 / 12 GLY A 382
GLY A 383
ARG A 366
ILE A 367
ASP A 418
 None
 0.84A 3ihtA-3qdrA:
undetectable		 3ihtA-3qdrA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 3qdr PROTEIN TOLA
(Escherichia
coli) 		5 / 12 GLY A 382
GLY A 383
THR A 362
ILE A 367
ASP A 418
 None
 0.85A 3ihtA-3qdrA:
undetectable		 3ihtA-3qdrA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3qdr PROTEIN TOLA
(Escherichia
coli) 		5 / 12 GLY A 342
SER A 346
ILE A 337
ASN A 338
PRO A 404
 None
 1.31A 4rtpA-3qdrA:
undetectable		 4rtpA-3qdrA:
19.59