SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qe7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 9 LEU A 322
ILE A 326
LEU A  25
GLY A  30
LEU A  47
 None
 1.11A 1e7aB-3qe7A:
undetectable		 1e7aB-3qe7A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 11 GLY A  93
ALA A  90
GLY A 281
PRO A  36
VAL A  35
 None
 0.98A 1hxwB-3qe7A:
undetectable		 1hxwB-3qe7A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 LEU A 147
GLY A 142
LEU A  38
LEU A 331
PHE A  73
 None
None
None
None
URA  A 430 (-3.4A)
 0.83A 1mx1D-3qe7A:
undetectable		 1mx1D-3qe7A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_0
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 GLY A 126
ALA A 123
SER A 370
ALA A 130
ILE A 350
 None
None
None
BNG  A 431 ( 4.2A)
BNG  A 431 (-4.8A)
 1.07A 1nt2A-3qe7A:
undetectable		 1nt2A-3qe7A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 GLY A 308
GLY A 307
SER A  21
LEU A  58
LEU A  14
 None
 1.03A 1ya4B-3qe7A:
undetectable		 1ya4B-3qe7A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 LEU A 134
GLY A 133
VAL A 344
ALA A  31
LEU A  34
 BNG  A 431 ( 4.7A)
BNG  A 431 (-3.2A)
None
URA  A 430 ( 3.8A)
None
 0.76A 2oz7A-3qe7A:
undetectable		 2oz7A-3qe7A:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 GLY A  93
ALA A  90
GLY A 281
PRO A  36
VAL A  35
 None
 0.95A 2q5kB-3qe7A:
undetectable		 2q5kB-3qe7A:
13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_A_X2NA1480_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 PHE A  73
PRO A  43
ALA A  44
ALA A 140
ALA A 144
 URA  A 430 (-3.4A)
None
None
None
None
 1.00A 2x2nA-3qe7A:
undetectable		 2x2nA-3qe7A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 PHE A  73
PRO A  43
ALA A  44
ALA A 140
ALA A 144
 URA  A 430 (-3.4A)
None
None
None
None
 0.96A 2x2nB-3qe7A:
undetectable		 2x2nB-3qe7A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 8 MET A 295
ALA A 296
GLY A 293
ILE A 292
 None
 0.68A 2zm9A-3qe7A:
undetectable		 2zm9A-3qe7A:
24.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 7 ILE A 329
GLY A  30
VAL A 191
LEU A 322
 None
 0.81A 3elzA-3qe7A:
undetectable		 3elzA-3qe7A:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 LEU A  91
GLN A 327
LEU A  80
VAL A  79
LEU A  83
 None
 1.14A 3gwxB-3qe7A:
undetectable		 3gwxB-3qe7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID6_C_SAMC301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 GLY A 126
ALA A 123
SER A 370
ALA A 130
ILE A 350
 None
None
None
BNG  A 431 ( 4.2A)
BNG  A 431 (-4.8A)
 1.18A 3id6C-3qe7A:
undetectable		 3id6C-3qe7A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		3 / 3 SER A  21
GLY A 308
SER A 302
 None
 0.53A 3loqA-3qe7A:
undetectable		 3loqA-3qe7A:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 6 THR A 220
GLY A 281
ILE A  41
LEU A 218
 None
 1.02A 4acbC-3qe7A:
undetectable		 4acbC-3qe7A:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 4 PRO A 184
LEU A 180
ILE A 297
ARG A 299
 None
 1.18A 4f4dA-3qe7A:
undetectable		 4f4dA-3qe7A:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 8 LEU A 236
PRO A 284
SER A  72
GLY A 271
 None
None
URA  A 430 (-4.4A)
None
 1.01A 4klrB-3qe7A:
undetectable		 4klrB-3qe7A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_B_CP6B201_1
(DIHYDROFOLATE
REDUCTASE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 ILE A 292
ALA A  67
ILE A  65
ILE A 252
THR A 287
 None
 1.06A 4km0B-3qe7A:
undetectable		 4km0B-3qe7A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 6 THR A 303
THR A 287
HIS A 242
LEU A 257
 None
 1.06A 4pgfA-3qe7A:
undetectable		 4pgfA-3qe7A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 9 ALA A 140
ILE A 329
GLY A  30
ALA A  31
VAL A  37
 None
None
None
URA  A 430 ( 3.8A)
None
 1.04A 4r1zA-3qe7A:
undetectable		 4r1zA-3qe7A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 8 LEU A 258
ASN A 251
ALA A 250
VAL A 253
 None
 0.92A 4zbqA-3qe7A:
undetectable		 4zbqA-3qe7A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 TYR A  68
ILE A  65
LEU A 257
THR A 303
GLY A  63
 None
 1.08A 5d4uA-3qe7A:
undetectable		 5d4uA-3qe7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 TYR A  68
ILE A  65
LEU A 257
THR A 303
GLY A  63
 None
 1.08A 5d4uB-3qe7A:
undetectable		 5d4uB-3qe7A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 8 ALA A  67
HIS A  24
ASN A 291
THR A 303
 None
 1.28A 5db5A-3qe7A:
undetectable
5db5B-3qe7A:
undetectable		 5db5A-3qe7A:
23.25
5db5B-3qe7A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K9D_A_CE9A402_0
(DIHYDROOROTATE
DEHYDROGENASE
(QUINONE),
MITOCHONDRIAL)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 ALA A  44
LEU A  47
TYR A 219
LEU A 218
THR A 217
 None
 1.11A 5k9dA-3qe7A:
undetectable		 5k9dA-3qe7A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 11 LEU A 339
GLU A 135
GLY A 133
SER A 338
ALA A 141
 None
None
BNG  A 431 (-3.2A)
None
None
 1.03A 5o96A-3qe7A:
undetectable
5o96B-3qe7A:
undetectable		 5o96A-3qe7A:
19.33
5o96B-3qe7A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 5 THR A 303
THR A 287
HIS A 242
LEU A 257
 None
 1.09A 6aphA-3qe7A:
undetectable		 6aphA-3qe7A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 11 ILE A 329
PRO A 330
PRO A 332
SER A 338
LEU A 339
 None
 1.37A 6dlzA-3qe7A:
undetectable
6dlzD-3qe7A:
2.9		 6dlzA-3qe7A:
11.06
6dlzD-3qe7A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 11 ILE A 329
PRO A 330
PRO A 332
SER A 338
LEU A 339
 None
 1.37A 6dm1A-3qe7A:
undetectable
6dm1D-3qe7A:
2.8		 6dm1A-3qe7A:
11.06
6dm1D-3qe7A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		4 / 5 THR A 303
THR A 287
HIS A 242
LEU A 257
 None
 1.12A 6gbnB-3qe7A:
undetectable		 6gbnB-3qe7A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 3qe7 URACIL PERMEASE
(Escherichia
coli) 		5 / 12 HIS A  24
PRO A 216
VAL A 294
GLU A 290
GLY A 289
 None
None
None
URA  A 430 (-2.6A)
BNG  A 431 ( 3.0A)
 1.40A 6gngA-3qe7A:
undetectable		 6gngA-3qe7A:
21.91