SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qef'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 12 LEU A  73
ALA A  55
ALA A  41
THR A 265
VAL A 297
 None
None
None
AHR  A 338 ( 4.8A)
None
 1.23A 1cbrA-3qefA:
undetectable		 1cbrA-3qefA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 12 LEU A  73
ALA A  55
ALA A  41
THR A 265
VAL A 297
 None
None
None
AHR  A 338 ( 4.8A)
None
 1.23A 1cbrB-3qefA:
undetectable		 1cbrB-3qefA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		3 / 3 THR A 158
PRO A 161
THR A 160
 None
 0.94A 1dscC-3qefA:
undetectable		 1dscC-3qefA:
3.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 9 PHE A 303
VAL A 320
GLY A 319
THR A 316
VAL A 314
 None
 1.44A 1dz8A-3qefA:
undetectable		 1dz8A-3qefA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 12 PHE A 129
ALA A  98
ALA A 150
GLY A 100
TRP A 103
 None
None
None
None
EDO  A 336 (-3.5A)
 1.25A 2igtC-3qefA:
undetectable		 2igtC-3qefA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 12 SER A 170
LEU A 256
SER A 229
ILE A 310
LEU A 302
 None
 1.13A 3ko0G-3qefA:
undetectable
3ko0H-3qefA:
undetectable
3ko0I-3qefA:
undetectable
3ko0J-3qefA:
undetectable		 3ko0G-3qefA:
17.26
3ko0H-3qefA:
17.26
3ko0I-3qefA:
17.26
3ko0J-3qefA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 11 ILE A 217
ILE A 246
SER A 245
PHE A 182
GLY A 248
 None
 0.84A 3kw4A-3qefA:
undetectable		 3kw4A-3qefA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5P_A_TACA7101_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 12 VAL A 219
TYR A 190
ILE A 238
PHE A 213
ILE A 207
 None
 1.43A 3q5pA-3qefA:
undetectable		 3q5pA-3qefA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5R_A_KANA2002_1
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 11 VAL A 219
TYR A 190
ILE A 238
PHE A 213
ILE A 207
 None
 1.43A 3q5rA-3qefA:
undetectable		 3q5rA-3qefA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		4 / 6 THR A 214
ASN A 185
GLY A 184
ASP A 168
 AHR  A 337 (-4.7A)
AHR  A 338 ( 3.2A)
None
None
 1.17A 3w9tE-3qefA:
undetectable		 3w9tE-3qefA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		5 / 12 PHE A  95
GLY A 136
GLY A 141
ASP A 145
ALA A 146
 None
 1.03A 4krhA-3qefA:
undetectable		 4krhA-3qefA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		4 / 6 THR A 214
THR A 263
HIS A 282
ASN A 257
 AHR  A 337 (-4.7A)
None
None
None
 1.27A 4pfjB-3qefA:
undetectable		 4pfjB-3qefA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		4 / 5 THR A 214
THR A 263
HIS A 282
ASN A 257
 AHR  A 337 (-4.7A)
None
None
None
 1.30A 4pgfB-3qefA:
undetectable		 4pgfB-3qefA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 3qef BETA-XYLOSIDASE/ALPH
A-L-ARABINFURANOSIDA
SE, GLY43N
(Cellvibrio
japonicus) 		3 / 3 TRP A  72
MET A  69
ASN A  70
 None
EDO  A 336 (-3.6A)
None
 1.48A 5uc1A-3qefA:
undetectable		 5uc1A-3qefA:
14.00