SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qeh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3qeh FAB FRAGMENT OF
HUMAN ANTI-HIV-1 ENV
ANTIBODY N12-I15,
HEAVY CHAIN
(Homo
sapiens) 		4 / 6 LEU A 189
GLY A 190
ALA A 125
PRO A 126
 None
 0.46A 3huoA-3qehA:
undetectable		 3huoA-3qehA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 3qeh FAB FRAGMENT OF
HUMAN ANTI-HIV-1 ENV
ANTIBODY N12-I15,
HEAVY CHAIN
(Homo
sapiens) 		5 / 10 TYR A 176
LEU A 108
VAL A  18
LEU A  82
LEU A 170
 None
 1.17A 5ienB-3qehA:
undetectable		 5ienB-3qehA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 3qeh FAB FRAGMENT OF
HUMAN ANTI-HIV-1 ENV
ANTIBODY N12-I15,
HEAVY CHAIN
(Homo
sapiens) 		3 / 3 PRO A 185
SER A 187
SER A 188
 None
 0.56A 6bpyA-3qehA:
undetectable		 6bpyA-3qehA:
20.95