SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qfe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4004_1
(SERUM ALBUMIN)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		4 / 4 VAL A 139
PHE A 195
SER A 193
VAL A 168
 None
 1.09A 1e7cA-3qfeA:
undetectable		 1e7cA-3qfeA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		4 / 5 VAL A  15
THR A  16
GLN A  30
ILE A 275
 None
 1.11A 1ss4A-3qfeA:
undetectable		 1ss4A-3qfeA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		5 / 10 ALA A 270
ALA A 265
ASN A  51
ALA A 278
ILE A  47
 None
 1.15A 2aclC-3qfeA:
undetectable		 2aclC-3qfeA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		4 / 7 PHE A  55
ILE A 123
ILE A 160
GLY A  84
 None
 0.97A 2v0mB-3qfeA:
undetectable		 2v0mB-3qfeA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		5 / 12 PHE A  55
PHE A 127
VAL A 170
LEU A 172
THR A 173
 None
 1.24A 3em0B-3qfeA:
undetectable		 3em0B-3qfeA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		5 / 9 LEU A  48
TYR A 141
ALA A 216
THR A 261
ILE A 258
 None
 1.03A 3jusB-3qfeA:
undetectable		 3jusB-3qfeA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		4 / 5 PHE A 192
PRO A 165
VAL A 167
ALA A 191
 None
 1.27A 4w5oA-3qfeA:
undetectable		 4w5oA-3qfeA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		4 / 5 PHE A 192
PRO A 165
VAL A 167
ALA A 191
 None
 1.29A 4z4cA-3qfeA:
2.5		 4z4cA-3qfeA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		4 / 5 PHE A 192
PRO A 165
VAL A 167
ALA A 191
 None
 1.29A 4z4dA-3qfeA:
2.6		 4z4dA-3qfeA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		4 / 5 PHE A 192
PRO A 165
VAL A 167
ALA A 191
 None
 1.27A 4z4eA-3qfeA:
undetectable		 4z4eA-3qfeA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 3qfe PUTATIVE
DIHYDRODIPICOLINATE
SYNTHASE FAMILY
PROTEIN
(Coccidioides
immitis) 		4 / 8 ALA A  63
ILE A  47
ALA A  81
LEU A  48
 None
 0.71A 5te8B-3qfeA:
undetectable		 5te8B-3qfeA:
21.56