SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qfg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3qfg UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		5 / 12 SER A  66
VAL A 173
ILE A 114
ILE A  73
ASP A 183
 None
 0.98A 1qhyA-3qfgA:
undetectable		 1qhyA-3qfgA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 3qfg UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 4 PHE A  69
LYS A  68
ILE A  64
THR A 154
 None
 1.26A 3ia4B-3qfgA:
undetectable		 3ia4B-3qfgA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3qfg UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 ASN A 172
TYR A 161
LEU A 127
PHE A  91
 None
 1.29A 4twdB-3qfgA:
undetectable
4twdC-3qfgA:
undetectable		 4twdB-3qfgA:
19.08
4twdC-3qfgA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3qfg UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 6 ASN A 172
TYR A 161
LEU A 127
PHE A  91
 None
 1.22A 4twdD-3qfgA:
undetectable
4twdE-3qfgA:
undetectable		 4twdD-3qfgA:
19.08
4twdE-3qfgA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3qfg UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 5 PHE A  69
PRO A 106
ALA A  71
PHE A 159
 None
 1.22A 4z4dA-3qfgA:
undetectable		 4z4dA-3qfgA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3qfg UNCHARACTERIZED
PROTEIN
(Staphylococcus
aureus) 		4 / 5 PHE A  69
PRO A 106
ALA A  71
PHE A 159
 None
 1.22A 4z4eA-3qfgA:
undetectable		 4z4eA-3qfgA:
14.07