SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.50A 1a4gA-3qfiA:
undetectable		 1a4gA-3qfiA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.45A 2cmlA-3qfiA:
undetectable		 2cmlA-3qfiA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.48A 2cmlB-3qfiA:
undetectable		 2cmlB-3qfiA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.45A 2cmlC-3qfiA:
undetectable		 2cmlC-3qfiA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.46A 2cmlD-3qfiA:
undetectable		 2cmlD-3qfiA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.47A 3b7eA-3qfiA:
undetectable		 3b7eA-3qfiA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.48A 3b7eB-3qfiA:
undetectable		 3b7eB-3qfiA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		4 / 5 ILE A 170
TYR A 195
ARG A 211
GLY A 208
 None
 1.23A 3b9mA-3qfiA:
undetectable		 3b9mA-3qfiA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 LEU A 138
GLN A 285
LEU A 272
THR A 295
LEU A 119
 None
 1.19A 3fsuA-3qfiA:
undetectable		 3fsuA-3qfiA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 PHE A  62
LEU A  66
VAL A 221
ALA A 263
PHE A 264
 None
 1.49A 3nuvA-3qfiA:
undetectable		 3nuvA-3qfiA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.47A 3ti5A-3qfiA:
undetectable		 3ti5A-3qfiA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.47A 3ti5B-3qfiA:
undetectable		 3ti5B-3qfiA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.48A 3ticA-3qfiA:
undetectable		 3ticA-3qfiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.46A 3ticB-3qfiA:
undetectable		 3ticB-3qfiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.47A 3ticC-3qfiA:
undetectable		 3ticC-3qfiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.47A 3ticD-3qfiA:
undetectable		 3ticD-3qfiA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.48A 4b7nA-3qfiA:
undetectable		 4b7nA-3qfiA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.47A 4b7qB-3qfiA:
undetectable		 4b7qB-3qfiA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 ARG A 197
ASP A  70
ARG A 104
ASN A 120
ARG A 209
 None
 1.48A 4b7qD-3qfiA:
undetectable		 4b7qD-3qfiA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		4 / 6 THR A 295
GLU A 270
THR A  85
LEU A 272
 None
 1.16A 4pgfA-3qfiA:
undetectable		 4pgfA-3qfiA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		4 / 6 PRO A 289
LEU A 316
PHE A 318
LEU A 292
 None
 1.16A 5tl8A-3qfiA:
undetectable		 5tl8A-3qfiA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 12 SER A 226
VAL A 216
VAL A 147
LEU A 157
VAL A 161
 None
 1.05A 5tudD-3qfiA:
undetectable		 5tudD-3qfiA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3qfi TRANSCRIPTIONAL
REGULATOR
(Enterococcus
faecalis) 		5 / 10 ASP A 206
GLY A 205
GLY A 208
GLN A 213
GLU A 204
 None
 1.38A 6nqaK-3qfiA:
undetectable		 6nqaK-3qfiA:
20.85