SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qfo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU A  53
ARG A  27
ALA A  24
LEU A   9
ILE A 185
 None
 1.03A 1g5yB-3qfoA:
undetectable		 1g5yB-3qfoA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICT_D_T44D129_1
(TRANSTHYRETIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 LEU A  37
ALA A  61
LEU A  36
THR A  60
 None
 1.08A 1ictB-3qfoA:
undetectable		 1ictB-3qfoA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 TYR A  34
LEU A  57
LEU A  53
ILE A 185
LEU A   9
 None
 1.13A 1tw4B-3qfoA:
undetectable		 1tw4B-3qfoA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 LEU A 178
LEU A 169
MET A 204
 None
 0.64A 1ya3B-3qfoA:
undetectable		 1ya3B-3qfoA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 6 LEU A  37
ALA A  61
LEU A  36
THR A  60
 None
 1.05A 2roxB-3qfoA:
undetectable		 2roxB-3qfoA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 PRO A  43
GLU A 241
TYR A 243
 None
 0.72A 2zmbA-3qfoA:
undetectable		 2zmbA-3qfoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 9 ASP A  39
ILE A  40
GLY A  14
VAL A  22
ILE A 185
 MN  A 265 (-2.7A)
None
None
None
None
 1.31A 3ekyB-3qfoA:
undetectable		 3ekyB-3qfoA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		4 / 7 LYS A 133
TYR A 162
ARG A 137
HIS A 141
 None
None
AMP  A 263 (-3.3A)
AMP  A 263 (-4.1A)
 1.43A 3frqB-3qfoA:
undetectable		 3frqB-3qfoA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 VAL A 221
ASP A 222
LEU A  19
THR A  45
LEU A 247
 None
 1.23A 3j6gB-3qfoA:
undetectable		 3j6gB-3qfoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_D_TA1D502_1
(TUBULIN BETA CHAIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 VAL A 221
ASP A 222
LEU A  19
THR A  45
LEU A 247
 None
 1.23A 3j6gD-3qfoA:
undetectable		 3j6gD-3qfoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 VAL A 221
ASP A 222
LEU A  19
THR A  45
LEU A 247
 None
 1.23A 3j6gF-3qfoA:
undetectable		 3j6gF-3qfoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_H_TA1H502_1
(TUBULIN BETA CHAIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 VAL A 221
ASP A 222
LEU A  19
THR A  45
LEU A 247
 None
 1.23A 3j6gH-3qfoA:
undetectable		 3j6gH-3qfoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_J_TA1J502_1
(TUBULIN BETA CHAIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 VAL A 221
ASP A 222
LEU A  19
THR A  45
LEU A 247
 None
 1.23A 3j6gJ-3qfoA:
undetectable		 3j6gJ-3qfoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_L_TA1L502_1
(TUBULIN BETA CHAIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 VAL A 221
ASP A 222
LEU A  19
THR A  45
LEU A 247
 None
 1.23A 3j6gL-3qfoA:
undetectable		 3j6gL-3qfoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_N_TA1N502_1
(TUBULIN BETA CHAIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 VAL A 221
ASP A 222
LEU A  19
THR A  45
LEU A 247
 None
 1.23A 3j6gN-3qfoA:
undetectable		 3j6gN-3qfoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_P_TA1P502_1
(TUBULIN BETA CHAIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 VAL A 221
ASP A 222
LEU A  19
THR A  45
LEU A 247
 None
 1.24A 3j6gP-3qfoA:
undetectable		 3j6gP-3qfoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6G_R_TA1R502_1
(TUBULIN BETA CHAIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 10 VAL A 221
ASP A 222
LEU A  19
THR A  45
LEU A 247
 None
 1.24A 3j6gR-3qfoA:
undetectable		 3j6gR-3qfoA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 GLY A  44
ALA A 232
LEU A 231
ILE A  40
LEU A  19
 None
 1.00A 3mb5A-3qfoA:
undetectable		 3mb5A-3qfoA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 GLN A 114
ALA A 160
ILE A 165
GLY A  65
ASP A  11
 None
None
AMP  A 263 (-4.6A)
None
FE  A 264 (-3.0A)
 1.07A 4iilA-3qfoA:
undetectable		 4iilA-3qfoA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 TYR A 243
SER A 246
THR A  16
THR A  17
ALA A  18
 None
 1.21A 4u15B-3qfoA:
undetectable		 4u15B-3qfoA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU A  19
LEU A  54
HIS A  13
LEU A  41
ILE A  50
 None
None
FE  A 264 ( 3.4A)
None
None
 1.13A 4x1fA-3qfoA:
undetectable		 4x1fA-3qfoA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 11 GLY A  14
GLY A  44
THR A  16
GLU A  20
ALA A  18
 None
 0.97A 5o96G-3qfoA:
undetectable		 5o96G-3qfoA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 3qfo PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
pneumoniae) 		5 / 12 LEU A 151
TYR A 162
LEU A 206
MET A 216
LEU A 169
 None
 1.30A 6ie8A-3qfoA:
undetectable		 6ie8A-3qfoA:
24.37