SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qfw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ASN A 192
HIS A 153
ALA A 156
GLY A 159
 None
 1.11A 1c8lA-3qfwA:
undetectable		 1c8lA-3qfwA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 VAL A 184
GLY A 185
ALA A 152
LEU A 138
 None
 0.80A 1e7bB-3qfwA:
undetectable		 1e7bB-3qfwA:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 ALA A 194
GLY A 158
GLY A 197
GLY A 196
LEU A 353
 None
 0.98A 1eizA-3qfwA:
2.2		 1eizA-3qfwA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 ALA A 194
GLY A 158
GLY A 197
GLY A 196
LEU A 353
 None
 0.96A 1ej0A-3qfwA:
undetectable		 1ej0A-3qfwA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ASN A 192
HIS A 153
ALA A 156
GLY A 159
 None
 1.11A 1gfzA-3qfwA:
2.1		 1gfzA-3qfwA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 8 LEU A 138
VAL A 188
GLY A 185
LEU A 155
 None
 0.97A 1jlbA-3qfwA:
2.3		 1jlbA-3qfwA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ASN A 192
HIS A 153
ALA A 156
GLY A 159
 None
 1.16A 1l5qB-3qfwA:
undetectable		 1l5qB-3qfwA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 8 LEU A 138
VAL A 188
GLY A 185
LEU A 155
 None
 0.98A 1s1xA-3qfwA:
undetectable		 1s1xA-3qfwA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 8 MET A 339
THR A 317
ALA A 319
VAL A 282
 None
 0.78A 1sn5C-3qfwA:
undetectable		 1sn5C-3qfwA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 8 TYR A 108
PHE A 112
PHE A 308
LEU A  87
 None
 1.18A 1x8vA-3qfwA:
undetectable		 1x8vA-3qfwA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 PRO A 231
PRO A 203
ILE A 205
VAL A 234
LEU A 209
 None
 1.44A 1z9hA-3qfwA:
undetectable		 1z9hA-3qfwA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 PRO A 231
PRO A 203
ILE A 205
VAL A 234
LEU A 209
 None
 1.43A 1z9hB-3qfwA:
undetectable		 1z9hB-3qfwA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 PRO A 231
PRO A 203
ILE A 205
VAL A 234
LEU A 209
 None
 1.45A 1z9hC-3qfwA:
undetectable		 1z9hC-3qfwA:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 8 LYS A 164
LEU A 341
HIS A 254
ALA A 319
 None
 0.80A 2bnnA-3qfwA:
undetectable
2bnnB-3qfwA:
undetectable		 2bnnA-3qfwA:
22.13
2bnnB-3qfwA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 LEU A 275
GLY A 113
LEU A 104
VAL A 102
GLY A  81
 None
 0.98A 2vmyA-3qfwA:
undetectable		 2vmyA-3qfwA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 LEU A 275
GLY A 114
LEU A 104
VAL A 102
GLY A  81
 None
 1.04A 2vmyA-3qfwA:
undetectable		 2vmyA-3qfwA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		3 / 3 GLU A 245
GLN A 215
ARG A 214
 None
 0.98A 2w3bB-3qfwA:
undetectable		 2w3bB-3qfwA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ASN A 192
HIS A 153
ALA A 156
GLY A 159
 None
 1.13A 3dd1A-3qfwA:
undetectable		 3dd1A-3qfwA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ASN A 192
HIS A 153
ALA A 156
GLY A 159
 None
 1.12A 3dd1B-3qfwA:
undetectable		 3dd1B-3qfwA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ASN A 192
HIS A 153
ALA A 156
GLY A 159
 None
 1.15A 3ddsA-3qfwA:
undetectable		 3ddsA-3qfwA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ASN A 192
HIS A 153
ALA A 156
GLY A 159
 None
 1.15A 3ddwA-3qfwA:
undetectable		 3ddwA-3qfwA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ASN A 192
HIS A 153
ALA A 156
GLY A 159
 None
 1.15A 3ddwB-3qfwA:
1.3		 3ddwB-3qfwA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ILE A 163
LYS A 139
ILE A 151
HIS A 153
 None
 1.09A 3eteA-3qfwA:
undetectable
3eteE-3qfwA:
undetectable		 3eteA-3qfwA:
21.83
3eteE-3qfwA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 7 LYS A 139
ILE A 151
HIS A 153
ILE A 163
 None
 1.08A 3eteD-3qfwA:
undetectable
3eteF-3qfwA:
undetectable		 3eteD-3qfwA:
21.83
3eteF-3qfwA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 VAL A 361
LEU A 157
GLY A 158
THR A 199
ILE A 163
 None
 1.19A 4o5fA-3qfwA:
undetectable
4o5fB-3qfwA:
undetectable		 4o5fA-3qfwA:
25.06
4o5fB-3qfwA:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 ILE A 205
ALA A 253
VAL A 251
VAL A 234
 None
 0.81A 5eclD-3qfwA:
undetectable		 5eclD-3qfwA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 6 LEU A 275
LEU A 267
PHE A 276
LEU A  84
 None
 0.99A 5gs4A-3qfwA:
undetectable		 5gs4A-3qfwA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 5 LEU A 275
LEU A 267
PHE A 276
LEU A  84
 None
 0.96A 5gtrA-3qfwA:
undetectable		 5gtrA-3qfwA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_1
(CYTOCHROME P450 3A4)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 12 ASP A 161
SER A 150
ILE A 151
THR A 134
ALA A 194
 None
 1.24A 5vcgA-3qfwA:
undetectable		 5vcgA-3qfwA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		5 / 10 ILE A 151
LEU A 138
LEU A 162
ALA A 135
LEU A 341
 None
 1.25A 5y7pB-3qfwA:
undetectable		 5y7pB-3qfwA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_A_CXQA507_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT
(Rhodopseudomonas
palustris) 		4 / 5 ARG A 214
ALA A 178
GLN A 215
ILE A 219
 None
 1.40A 6f6sA-3qfwA:
undetectable
6f6sB-3qfwA:
undetectable		 6f6sA-3qfwA:
11.29
6f6sB-3qfwA:
13.68