SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qg5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 ILE A 777
ALA A 773
ARG A 741
LEU A 821
PHE A 827
 None
 1.32A 1y0xX-3qg5A:
undetectable		 1y0xX-3qg5A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 3qg5 RAD50
(Thermotoga
maritima) 		4 / 7 ILE A 811
PHE A 838
ILE A  25
PHE A 827
 None
 1.14A 2q6hA-3qg5A:
undetectable		 2q6hA-3qg5A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 3qg5 RAD50
(Thermotoga
maritima) 		4 / 7 ILE A 811
PHE A 838
ILE A  25
PHE A 827
 None
 1.13A 2qb4A-3qg5A:
3.9		 2qb4A-3qg5A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2001_1
(SERUM ALBUMIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 ARG A   2
PHE A 795
ILE A 129
ARG A 790
GLY A 789
 None
 1.44A 2vufA-3qg5A:
1.1		 2vufA-3qg5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2001_1
(SERUM ALBUMIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 ARG A   2
PHE A 795
ILE A 129
ARG A 790
GLY A 789
 None
 1.49A 2vufB-3qg5A:
2.2		 2vufB-3qg5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 770
ALA A 764
ILE A 755
LEU A 779
ILE A 777
 None
 1.02A 3adsB-3qg5A:
undetectable		 3adsB-3qg5A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3qg5 RAD50
(Thermotoga
maritima) 		6 / 12 LEU A 148
GLY A 770
ALA A 764
ILE A 755
LEU A 779
ILE A 777
 GOL  A3968 ( 4.4A)
None
None
None
None
None
 1.04A 3adxB-3qg5A:
undetectable		 3adxB-3qg5A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.02A 3uboB-3qg5A:
undetectable		 3uboB-3qg5A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.03A 4e3aA-3qg5A:
undetectable		 4e3aA-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.03A 4jkuB-3qg5A:
undetectable		 4jkuB-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.04A 4k8pA-3qg5A:
undetectable		 4k8pA-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.04A 4k8pB-3qg5A:
undetectable		 4k8pB-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.04A 4k8tA-3qg5A:
undetectable		 4k8tA-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.03A 4k93A-3qg5A:
undetectable		 4k93A-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.03A 4k93B-3qg5A:
undetectable		 4k93B-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.03A 4k9cA-3qg5A:
undetectable		 4k9cA-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.02A 4k9cB-3qg5A:
undetectable		 4k9cB-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.03A 4k9iA-3qg5A:
undetectable		 4k9iA-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.05A 4k9iB-3qg5A:
undetectable		 4k9iB-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.05A 4kadA-3qg5A:
undetectable		 4kadA-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.04A 4kadB-3qg5A:
undetectable		 4kadB-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LA0_B_198B601_1
(SERUM ALBUMIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 9 LEU A 774
ALA A 837
PHE A 838
GLU A 817
PHE A 834
 None
 1.36A 4la0B-3qg5A:
4.1		 4la0B-3qg5A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.04A 4lbxA-3qg5A:
undetectable		 4lbxA-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.05A 4lbxB-3qg5A:
undetectable		 4lbxB-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.04A 4lc4A-3qg5A:
undetectable		 4lc4A-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 12 GLY A 751
GLY A 752
SER A 151
LEU A 779
ASP A 748
 None
 1.04A 4lc4B-3qg5A:
undetectable		 4lc4B-3qg5A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3qg5 RAD50
(Thermotoga
maritima) 		4 / 8 PHE A 753
ALA A 780
LEU A 148
PHE A 714
 None
GOL  A3968 ( 4.6A)
GOL  A3968 ( 4.4A)
None
 0.98A 4rkuA-3qg5A:
2.5
4rkuJ-3qg5A:
undetectable		 4rkuA-3qg5A:
19.19
4rkuJ-3qg5A:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3qg5 RAD50
(Thermotoga
maritima) 		5 / 11 GLY A 770
ALA A 764
ILE A 755
LEU A 779
ILE A 777
 None
 1.01A 4xumB-3qg5A:
undetectable		 4xumB-3qg5A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)		 3qg5 RAD50
(Thermotoga
maritima) 		4 / 5 HIS A 131
SER A  44
GLY A  51
TYR A  60
 None
 1.40A 5yodH-3qg5A:
undetectable		 5yodH-3qg5A:
17.53