SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qgh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 10 ALA A  88
LEU A  83
LEU A  82
ILE A 253
LEU A 285
 None
 1.22A 1a52A-3qghA:
undetectable		 1a52A-3qghA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 7 ARG A 158
ASP A 318
ASP A 319
TYR A 448
 None
None
None
63F  A 601 (-4.1A)
 1.40A 1ceaB-3qghA:
undetectable		 1ceaB-3qghA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 5 GLU A 398
ALA A 400
SER A  27
HIS A 428
 None
 1.23A 1errA-3qghA:
undetectable
1errB-3qghA:
undetectable		 1errA-3qghA:
19.03
1errB-3qghA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 8 SER A  96
ALA A  97
GLY A 283
ILE A 160
 None
 0.74A 1gtnI-3qghA:
undetectable
1gtnJ-3qghA:
undetectable		 1gtnI-3qghA:
9.96
1gtnJ-3qghA:
9.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 4 SER A 371
LEU A 419
TYR A 383
GLY A 480
 None
 1.45A 1liiA-3qghA:
undetectable		 1liiA-3qghA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 8 GLU A 481
GLY A 480
THR A 364
ASP A 387
 None
 0.90A 1m4iA-3qghA:
undetectable		 1m4iA-3qghA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 10 ALA A  88
LEU A  83
LEU A  82
ILE A 253
LEU A 285
 None
 1.19A 1pcgA-3qghA:
undetectable		 1pcgA-3qghA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 12 THR A 229
PHE A 224
SER A 231
VAL A  71
ALA A 299
 None
 1.18A 1q23A-3qghA:
2.2
1q23B-3qghA:
2.2		 1q23A-3qghA:
16.58
1q23B-3qghA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 11 THR A 229
PHE A 224
SER A 231
LEU A  68
VAL A  71
 None
 1.44A 1q23G-3qghA:
2.2		 1q23G-3qghA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 11 THR A 229
PHE A 224
SER A 231
LEU A  68
VAL A  71
 None
 1.44A 1q23L-3qghA:
2.2		 1q23L-3qghA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 10 ALA A  88
LEU A  83
LEU A  82
ILE A 253
LEU A 285
 None
 1.26A 1qkuA-3qghA:
undetectable		 1qkuA-3qghA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 10 ALA A  88
LEU A  83
LEU A  82
ILE A 253
LEU A 285
 None
 1.27A 1qkuB-3qghA:
undetectable		 1qkuB-3qghA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 10 ALA A  88
LEU A  83
LEU A  82
ILE A 253
LEU A 285
 None
 1.27A 1qkuC-3qghA:
undetectable		 1qkuC-3qghA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9U_A_CPFA5002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 6 PHE A 429
PHE A 430
ASN A 406
GLN A 438
 None
 1.21A 1t9uA-3qghA:
4.4		 1t9uA-3qghA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 12 LEU A 204
ASP A 319
ARG A 200
CYH A 295
ALA A 299
 None
 1.30A 2bm9B-3qghA:
undetectable		 2bm9B-3qghA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 7 TYR A 191
GLY A 317
THR A 292
ASP A 318
 63F  A 601 (-4.9A)
None
63F  A 601 ( 4.7A)
None
 1.07A 2g70A-3qghA:
undetectable		 2g70A-3qghA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFH_A_CL6A1413_1
(ERYTHROMYCIN B/D
C-12 HYDROXYLASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 6 ALA A 393
ALA A 396
THR A 399
PHE A 429
 None
 0.86A 2xfhA-3qghA:
undetectable		 2xfhA-3qghA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 12 ALA A  45
PRO A 265
THR A 267
THR A 136
LEU A  10
 None
 1.22A 2zifA-3qghA:
undetectable		 2zifA-3qghA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 11 ALA A 174
LEU A  83
SER A  84
VAL A  85
ALA A  88
 None
 0.74A 3dcmX-3qghA:
undetectable		 3dcmX-3qghA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 12 ALA A  88
LEU A  83
LEU A  82
ILE A 253
LEU A 285
 None
 1.15A 3q95A-3qghA:
undetectable		 3q95A-3qghA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 7 SER A 190
TYR A 296
VAL A  67
TYR A 219
 None
 1.05A 3tneB-3qghA:
undetectable		 3tneB-3qghA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 10 THR A 229
PHE A 224
SER A 231
LEU A  68
VAL A  71
 None
 1.50A 3u9fK-3qghA:
2.1		 3u9fK-3qghA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 12 THR A 229
PHE A 224
SER A 231
LEU A  68
VAL A  71
 None
 1.42A 3u9fJ-3qghA:
2.1
3u9fL-3qghA:
undetectable		 3u9fJ-3qghA:
16.58
3u9fL-3qghA:
16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		3 / 3 TYR A 358
MET A 313
LEU A 308
 None
 0.87A 3vw1D-3qghA:
undetectable		 3vw1D-3qghA:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 6 CYH A 295
THR A 294
ASN A 291
GLY A 317
 None
 1.33A 3w9tE-3qghA:
undetectable		 3w9tE-3qghA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 12 LEU A 409
LEU A 425
MET A 426
ILE A 462
ILE A 463
 None
None
None
63F  A 601 (-4.0A)
None
 0.99A 4j24B-3qghA:
undetectable		 4j24B-3qghA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 6 SER A 121
GLY A 104
ASP A 107
GLY A 102
 None
 0.89A 4koeA-3qghA:
2.9
4koeB-3qghA:
2.8
4koeC-3qghA:
undetectable		 4koeA-3qghA:
21.65
4koeB-3qghA:
21.65
4koeC-3qghA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 7 GLY A 558
ASP A 559
GLY A 449
GLU A 446
 None
 0.87A 4koeA-3qghA:
2.9
4koeB-3qghA:
2.8
4koeD-3qghA:
undetectable		 4koeA-3qghA:
21.65
4koeB-3qghA:
21.65
4koeD-3qghA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 7 SER A 121
GLY A 104
ASP A 107
GLY A 102
 None
 0.91A 4koeA-3qghA:
2.9
4koeB-3qghA:
2.8
4koeD-3qghA:
undetectable		 4koeA-3qghA:
21.65
4koeB-3qghA:
21.65
4koeD-3qghA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 5 LEU A 419
SER A 478
LEU A 497
ASN A 369
 None
 1.17A 4n09B-3qghA:
undetectable		 4n09B-3qghA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 11 THR A 136
THR A 137
GLY A 283
ALA A 281
THR A 287
 None
 1.25A 4qw0V-3qghA:
undetectable
4qw0b-3qghA:
undetectable		 4qw0V-3qghA:
18.08
4qw0b-3qghA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 11 THR A 136
THR A 137
GLY A 283
ALA A 281
THR A 287
 None
 1.25A 4qw0H-3qghA:
undetectable
4qw0N-3qghA:
undetectable		 4qw0H-3qghA:
18.08
4qw0N-3qghA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		3 / 3 LYS A 141
ARG A 168
VAL A 284
 None
 1.03A 4x3uA-3qghA:
undetectable
4x3uB-3qghA:
undetectable		 4x3uA-3qghA:
8.12
4x3uB-3qghA:
8.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 6 GLY A 104
ASP A 107
GLY A 102
SER A 121
 None
 0.92A 4z53A-3qghA:
2.7
4z53B-3qghA:
2.7		 4z53A-3qghA:
21.96
4z53B-3qghA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 7 GLY A 104
ASP A 107
GLY A 102
SER A 121
 None
 0.93A 4z53A-3qghA:
2.7
4z53B-3qghA:
2.7		 4z53A-3qghA:
21.96
4z53B-3qghA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 7 GLY A 558
ASP A 559
GLY A 449
GLU A 446
 None
 0.97A 4z53A-3qghA:
2.7
4z53B-3qghA:
2.7		 4z53A-3qghA:
21.96
4z53B-3qghA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 11 THR A 136
THR A 137
GLY A 283
ALA A 281
THR A 287
 None
 1.24A 5d0xV-3qghA:
undetectable
5d0xb-3qghA:
undetectable		 5d0xV-3qghA:
18.08
5d0xb-3qghA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 11 THR A 136
THR A 137
GLY A 283
ALA A 281
THR A 287
 None
 1.24A 5d0xH-3qghA:
undetectable
5d0xN-3qghA:
undetectable		 5d0xH-3qghA:
18.08
5d0xN-3qghA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 5 PHE A 551
GLY A 543
ASP A 458
ILE A 462
 63F  A 601 (-4.3A)
None
None
63F  A 601 (-4.0A)
 0.78A 5ik1A-3qghA:
undetectable		 5ik1A-3qghA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JCN_B_ASCB502_0
(OS09G0567300 PROTEIN)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 6 GLU A 236
GLY A 290
ARG A 280
PHE A 224
 None
 1.06A 5jcnB-3qghA:
undetectable		 5jcnB-3qghA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		5 / 12 LEU A 285
LEU A 175
ALA A 252
TRP A 123
LEU A 245
 None
 1.11A 5mwyA-3qghA:
undetectable		 5mwyA-3qghA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 6 ILE A 119
TYR A 103
LEU A 165
ARG A 168
 None
 1.28A 6f6jA-3qghA:
undetectable		 6f6jA-3qghA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3qgh RNA-DIRECTED RNA
POLYMERASE
(Hepacivirus
C) 		4 / 8 ASP A  61
ARG A 345
VAL A  71
ARG A 280
 None
 1.09A 6fbvD-3qghA:
undetectable		 6fbvD-3qghA:
18.45