SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qgk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E9Y_B_HAEB800_1
(UREASE SUBUNIT BETA)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 5 HIS C 135
HIS C 220
HIS C 247
HIS C 273
ASP C 361
 FE  C 775 (-3.5A)
KCX  C 218 (-4.2A)
FE  C 774 (-3.4A)
FE  C 774 (-3.3A)
FE  C 775 (-2.5A)
 0.37A 1e9yB-3qgkC:
60.6		 1e9yB-3qgkC:
74.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FWE_C_HAEC989_1
(UREASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		6 / 6 HIS C 135
HIS C 137
HIS C 220
HIS C 247
HIS C 273
ASP C 361
 FE  C 775 (-3.5A)
FE  C 775 (-3.3A)
KCX  C 218 (-4.2A)
FE  C 774 (-3.4A)
FE  C 774 (-3.3A)
FE  C 775 (-2.5A)
 0.34A 1fweC-3qgkC:
60.4		 1fweC-3qgkC:
59.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 ASP C 361
HIS C 273
HIS C 135
 FE  C 775 (-2.5A)
FE  C 774 (-3.3A)
FE  C 775 (-3.5A)
 0.66A 1oe1A-3qgkC:
undetectable		 1oe1A-3qgkC:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 ASP C 361
HIS C 273
HIS C 135
 FE  C 775 (-2.5A)
FE  C 774 (-3.3A)
FE  C 775 (-3.5A)
 0.66A 1oe3A-3qgkC:
undetectable		 1oe3A-3qgkC:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 169
GLY C 159
ILE C 171
PRO C 173
 None
None
KCX  C 218 ( 4.7A)
None
 0.83A 1rxcB-3qgkC:
undetectable		 1rxcB-3qgkC:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 169
GLY C 159
ILE C 171
PRO C 173
 None
None
KCX  C 218 ( 4.7A)
None
 0.80A 1rxcE-3qgkC:
undetectable		 1rxcE-3qgkC:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 169
GLY C 159
ILE C 171
PRO C 173
 None
None
KCX  C 218 ( 4.7A)
None
 0.84A 1rxcI-3qgkC:
undetectable		 1rxcI-3qgkC:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 169
GLY C 159
ILE C 171
PRO C 173
 None
None
KCX  C 218 ( 4.7A)
None
 0.82A 1rxcK-3qgkC:
undetectable		 1rxcK-3qgkC:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 ASP C  24
PHE A 105
ARG C 564
 None
 0.81A 2a3aA-3qgkC:
2.8		 2a3aA-3qgkC:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 10 ALA C 184
ALA C 185
ASN C 191
PHE C 138
ILE C 215
 None
 1.12A 2aclC-3qgkC:
undetectable		 2aclC-3qgkC:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 THR C 302
PRO C 304
PRO C 301
 None
 0.81A 2d55C-3qgkC:
undetectable		 2d55C-3qgkC:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 ASP C 102
ASN C 100
THR C 117
 None
 0.79A 2q63B-3qgkC:
undetectable		 2q63B-3qgkC:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 GLY C  86
HIS C  93
ALA C  98
HIS C 110
 None
 0.89A 2x0pA-3qgkC:
undetectable		 2x0pA-3qgkC:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 ASP C 361
HIS C 273
HIS C 135
 FE  C 775 (-2.5A)
FE  C 774 (-3.3A)
FE  C 775 (-3.5A)
 0.66A 2xxgA-3qgkC:
undetectable		 2xxgA-3qgkC:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 ASP C 361
HIS C 273
HIS C 135
 FE  C 775 (-2.5A)
FE  C 774 (-3.3A)
FE  C 775 (-3.5A)
 0.66A 2xxgC-3qgkC:
undetectable		 2xxgC-3qgkC:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 7 ASN A  76
GLY A  73
VAL A  70
ASP C  24
 None
 0.87A 2y05A-3qgkA:
undetectable
2y05B-3qgkA:
undetectable		 2y05A-3qgkA:
24.14
2y05B-3qgkA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 5 GLN C 209
THR C 172
THR C 491
LEU C 506
 None
 1.36A 2zj0A-3qgkC:
undetectable		 2zj0A-3qgkC:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 MET C 365
GLU C 221
ASN C 252
 None
 1.02A 3a27A-3qgkC:
undetectable		 3a27A-3qgkC:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 7 ASP C 133
SER C 298
GLU C 346
ASP C 347
 None
 1.17A 3bc9A-3qgkC:
4.1		 3bc9A-3qgkC:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB501_2
(PHOSPHOLIPASE A2)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 VAL C  68
LEU C  65
GLY C  86
ILE C  92
THR C 108
 None
 1.26A 3bjwB-3qgkC:
undetectable		 3bjwB-3qgkC:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 5 GLN C 209
THR C 172
THR C 491
LEU C 506
 None
 1.34A 3ce6A-3qgkC:
undetectable		 3ce6A-3qgkC:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 5 GLN C 209
THR C 172
THR C 491
LEU C 506
 None
 1.32A 3ce6C-3qgkC:
undetectable		 3ce6C-3qgkC:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 ALA C 289
GLY C 276
ILE C 294
SER C 297
ALA C 271
 None
 0.93A 3dcmX-3qgkC:
undetectable		 3dcmX-3qgkC:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 12 ALA C 184
ALA C 185
ASN C 191
PHE C 138
ILE C 215
 None
 1.04A 3e00A-3qgkC:
undetectable		 3e00A-3qgkC:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 TYR C  38
ASP C  18
HIS C  33
 None
 0.96A 3e23A-3qgkC:
undetectable		 3e23A-3qgkC:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 7 ILE C 132
PHE C 138
PHE C 144
GLY C 151
 None
 1.05A 3em0B-3qgkC:
undetectable		 3em0B-3qgkC:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_0
(REPRESSOR PROTEIN
MPHR(A))		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae;
Helicobacter
mustelae) 		5 / 12 GLY A 191
LEU C  42
SER A 170
ILE A 195
ILE C  50
 None
 1.06A 3frqB-3qgkA:
undetectable		 3frqB-3qgkA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
(Helicobacter
mustelae) 		5 / 12 ILE A 224
LEU A 129
VAL A 131
VAL A 184
LEU A 186
 None
 1.02A 3gwxB-3qgkA:
undetectable		 3gwxB-3qgkA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 10 THR C 166
LEU C 139
GLN C 143
SER C 362
HIS C 135
 None
None
None
None
FE  C 775 (-3.5A)
 1.37A 3kp3A-3qgkC:
0.0
3kp3B-3qgkC:
0.0		 3kp3A-3qgkC:
15.69
3kp3B-3qgkC:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 12 LEU C 317
GLY C 280
VAL C 257
ALA C 277
ILE C 274
 None
 0.96A 3ku1G-3qgkC:
undetectable		 3ku1G-3qgkC:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 12 LEU C 317
GLY C 280
VAL C 257
ALA C 277
ILE C 274
 None
 1.02A 3ku1H-3qgkC:
undetectable		 3ku1H-3qgkC:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 4 SER C 134
SER C 297
THR C 358
SER C 359
 None
 1.25A 3loqA-3qgkC:
0.0		 3loqA-3qgkC:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 7 PRO C 301
LEU C 314
GLY C 278
GLU C 275
 None
 0.96A 3tehB-3qgkC:
undetectable		 3tehB-3qgkC:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 5 ASP C  76
GLY C 423
TYR C  77
GLU C 426
 None
 0.94A 3w9tA-3qgkC:
undetectable		 3w9tA-3qgkC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 6 ASP C  76
GLY C 423
TYR C  77
GLU C 426
 None
 0.93A 3w9tB-3qgkC:
undetectable		 3w9tB-3qgkC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 5 ASP C  76
GLY C 423
TYR C  77
GLU C 426
 None
 0.93A 3w9tC-3qgkC:
undetectable		 3w9tC-3qgkC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1005_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 ASP C  76
GLY C 423
TYR C  77
 None
 0.76A 3w9tC-3qgkC:
undetectable		 3w9tC-3qgkC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 5 ASP C  76
GLY C 423
TYR C  77
GLU C 426
 None
 0.93A 3w9tD-3qgkC:
undetectable		 3w9tD-3qgkC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 6 ASP C  76
GLY C 423
TYR C  77
GLU C 426
 None
 0.94A 3w9tE-3qgkC:
undetectable		 3w9tE-3qgkC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 6 ASP C  76
GLY C 423
TYR C  77
GLU C 426
 None
 0.93A 3w9tF-3qgkC:
undetectable		 3w9tF-3qgkC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 5 ASP C  76
GLY C 423
TYR C  77
GLU C 426
 None
 0.93A 3w9tG-3qgkC:
undetectable		 3w9tG-3qgkC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG503_1
(HEMOLYTIC LECTIN
CEL-III)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		3 / 3 ASP C  76
GLY C 423
TYR C  77
 None
 0.76A 3w9tG-3qgkC:
undetectable		 3w9tG-3qgkC:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 169
GLY C 159
ILE C 171
PRO C 173
 None
None
KCX  C 218 ( 4.7A)
None
 0.83A 4e1vC-3qgkC:
undetectable		 4e1vC-3qgkC:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 169
GLY C 159
ILE C 171
PRO C 173
 None
None
KCX  C 218 ( 4.7A)
None
 0.82A 4e1vD-3qgkC:
undetectable		 4e1vD-3qgkC:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 169
GLY C 159
ILE C 171
PRO C 173
 None
None
KCX  C 218 ( 4.7A)
None
 0.82A 4e1vE-3qgkC:
undetectable		 4e1vE-3qgkC:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 169
GLY C 158
ILE C 171
PRO C 173
 None
None
KCX  C 218 ( 4.7A)
None
 0.93A 4e1vG-3qgkC:
undetectable		 4e1vG-3qgkC:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 169
GLY C 159
ILE C 171
PRO C 173
 None
None
KCX  C 218 ( 4.7A)
None
 0.81A 4e1vH-3qgkC:
undetectable		 4e1vH-3qgkC:
20.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H9M_A_HAEA929_1
(UREASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 5 HIS C 135
HIS C 220
HIS C 247
HIS C 273
ASP C 361
 FE  C 775 (-3.5A)
KCX  C 218 (-4.2A)
FE  C 774 (-3.4A)
FE  C 774 (-3.3A)
FE  C 775 (-2.5A)
 0.25A 4h9mA-3qgkC:
56.8		 4h9mA-3qgkC:
39.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 4qvlV-3qgkC:
undetectable
4qvlb-3qgkC:
undetectable		 4qvlV-3qgkC:
18.73
4qvlb-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.42A 4qvlH-3qgkC:
undetectable
4qvlN-3qgkC:
undetectable		 4qvlH-3qgkC:
18.73
4qvlN-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 4qvmV-3qgkC:
undetectable
4qvmb-3qgkC:
undetectable		 4qvmV-3qgkC:
18.73
4qvmb-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 4qvmH-3qgkC:
undetectable
4qvmN-3qgkC:
undetectable		 4qvmH-3qgkC:
18.73
4qvmN-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 4qvpV-3qgkC:
undetectable
4qvpb-3qgkC:
undetectable		 4qvpV-3qgkC:
18.73
4qvpb-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 4qvpH-3qgkC:
undetectable
4qvpN-3qgkC:
undetectable		 4qvpH-3qgkC:
18.73
4qvpN-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 4qvqV-3qgkC:
undetectable
4qvqb-3qgkC:
undetectable		 4qvqV-3qgkC:
18.73
4qvqb-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 4qvqH-3qgkC:
undetectable
4qvqN-3qgkC:
undetectable		 4qvqH-3qgkC:
18.73
4qvqN-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 10 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 4qvvV-3qgkC:
0.0
4qvvb-3qgkC:
0.0		 4qvvV-3qgkC:
18.73
4qvvb-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 10 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 4qvvH-3qgkC:
undetectable
4qvvN-3qgkC:
undetectable		 4qvvH-3qgkC:
18.73
4qvvN-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 4qvwV-3qgkC:
undetectable
4qvwb-3qgkC:
undetectable		 4qvwV-3qgkC:
18.73
4qvwb-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 4qvwH-3qgkC:
undetectable
4qvwN-3qgkC:
undetectable		 4qvwH-3qgkC:
18.73
4qvwN-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 4qw0H-3qgkC:
undetectable
4qw0N-3qgkC:
undetectable		 4qw0H-3qgkC:
18.73
4qw0N-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 4qw1V-3qgkC:
undetectable
4qw1b-3qgkC:
undetectable		 4qw1V-3qgkC:
18.73
4qw1b-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 4qw1H-3qgkC:
undetectable
4qw1N-3qgkC:
undetectable		 4qw1H-3qgkC:
18.73
4qw1N-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 4qw3V-3qgkC:
undetectable
4qw3b-3qgkC:
undetectable		 4qw3V-3qgkC:
18.73
4qw3b-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 4qw3H-3qgkC:
undetectable
4qw3N-3qgkC:
undetectable		 4qw3H-3qgkC:
18.73
4qw3N-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.39A 4qwuV-3qgkC:
undetectable
4qwub-3qgkC:
undetectable		 4qwuV-3qgkC:
18.73
4qwub-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 4qwuH-3qgkC:
undetectable
4qwuN-3qgkC:
undetectable		 4qwuH-3qgkC:
18.73
4qwuN-3qgkC:
15.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		6 / 6 HIS C 135
HIS C 137
HIS C 220
HIS C 247
HIS C 273
ASP C 361
 FE  C 775 (-3.5A)
FE  C 775 (-3.3A)
KCX  C 218 (-4.2A)
FE  C 774 (-3.4A)
FE  C 774 (-3.3A)
FE  C 775 (-2.5A)
 0.23A 4ubpC-3qgkC:
60.0		 4ubpC-3qgkC:
60.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 12 GLY C 130
PHE C 492
PHE C 156
ILE C 132
ALA C 413
 None
 1.06A 4wh5A-3qgkC:
undetectable		 4wh5A-3qgkC:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.44A 5bxnV-3qgkC:
undetectable
5bxnb-3qgkC:
undetectable		 5bxnV-3qgkC:
18.55
5bxnb-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.45A 5bxnH-3qgkC:
undetectable
5bxnN-3qgkC:
undetectable		 5bxnH-3qgkC:
18.55
5bxnN-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 9 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 5cz7V-3qgkC:
0.0
5cz7b-3qgkC:
0.0		 5cz7V-3qgkC:
18.73
5cz7b-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.39A 5cz7H-3qgkC:
undetectable
5cz7N-3qgkC:
undetectable		 5cz7H-3qgkC:
18.73
5cz7N-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.39A 5d0xV-3qgkC:
undetectable
5d0xb-3qgkC:
undetectable		 5d0xV-3qgkC:
18.73
5d0xb-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 5d0xH-3qgkC:
undetectable
5d0xN-3qgkC:
undetectable		 5d0xH-3qgkC:
18.73
5d0xN-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae;
Helicobacter
mustelae) 		3 / 3 MET C 103
GLN C 104
ARG A 165
 None
 1.05A 5ewzB-3qgkC:
undetectable		 5ewzB-3qgkC:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 8 THR C 136
CYH C 245
TYR C 272
LEU C 195
 None
None
KCX  C 218 ( 4.5A)
KCX  C 218 ( 4.2A)
 1.45A 5kxiA-3qgkC:
undetectable
5kxiB-3qgkC:
undetectable		 5kxiA-3qgkC:
19.07
5kxiB-3qgkC:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 5l5fV-3qgkC:
undetectable
5l5fb-3qgkC:
undetectable		 5l5fV-3qgkC:
18.73
5l5fb-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 5l5fH-3qgkC:
undetectable
5l5fN-3qgkC:
undetectable		 5l5fH-3qgkC:
18.73
5l5fN-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.41A 5l66V-3qgkC:
undetectable
5l66b-3qgkC:
undetectable		 5l66V-3qgkC:
18.73
5l66b-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 11 SER C 362
THR C 170
THR C 169
THR C 166
THR C 299
 None
KCX  C 218 ( 3.4A)
None
None
None
 1.40A 5l66H-3qgkC:
undetectable
5l66N-3qgkC:
undetectable		 5l66H-3qgkC:
18.73
5l66N-3qgkC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 10 LYS C  43
ALA C 121
GLY C 122
THR C  70
ASP C  34
 None
 1.18A 5lf3V-3qgkC:
undetectable
5lf3W-3qgkC:
undetectable		 5lf3V-3qgkC:
20.14
5lf3W-3qgkC:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae;
Helicobacter
mustelae) 		3 / 3 MET C 103
GLN C 104
ARG A 165
 None
 0.99A 5m35B-3qgkC:
undetectable		 5m35B-3qgkC:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae;
Helicobacter
mustelae) 		3 / 3 MET C 103
GLN C 104
ARG A 165
 None
 0.99A 5m36A-3qgkC:
undetectable		 5m36A-3qgkC:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 4 GLN C 209
THR C 172
THR C 491
LEU C 506
 None
 1.50A 5m5kA-3qgkC:
undetectable		 5m5kA-3qgkC:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 4 GLN C 209
THR C 172
THR C 491
LEU C 506
 None
 1.49A 5m5kC-3qgkC:
undetectable		 5m5kC-3qgkC:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 4 ASP C 361
HIS C 273
HIS C 247
HIS C 137
 FE  C 775 (-2.5A)
FE  C 774 (-3.3A)
FE  C 774 (-3.4A)
FE  C 775 (-3.3A)
 1.50A 5ncdD-3qgkC:
undetectable		 5ncdD-3qgkC:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		6 / 12 LEU C 194
ALA C 212
ILE C 215
GLY C 216
LEU C 182
LEU C 506
 None
 1.40A 5nfjA-3qgkC:
undetectable		 5nfjA-3qgkC:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
(Helicobacter
mustelae) 		5 / 9 ILE A 100
GLY A  75
GLY A  73
LEU A  30
ALA A  35
 None
 0.99A 5o96A-3qgkA:
undetectable
5o96B-3qgkA:
undetectable		 5o96A-3qgkA:
25.65
5o96B-3qgkA:
25.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 4 LEU C 219
GLY C 198
SER C 200
SER C 201
 KCX  C 218 ( 4.3A)
KCX  C 218 ( 3.6A)
None
None
 1.33A 5uunA-3qgkC:
undetectable		 5uunA-3qgkC:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB306_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 4 LEU C 219
GLY C 198
SER C 200
SER C 201
 KCX  C 218 ( 4.3A)
KCX  C 218 ( 3.6A)
None
None
 1.31A 5uunB-3qgkC:
undetectable		 5uunB-3qgkC:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		5 / 12 ILE C 401
PHE C 441
ILE C 405
ALA C 129
ILE C  85
 None
 1.11A 5vceA-3qgkC:
undetectable		 5vceA-3qgkC:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WQP_A_NCAA302_0
(PROBABLE
DEHYDROGENASE)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae;
Helicobacter
mustelae) 		4 / 8 SER A 170
TYR C  12
HIS A 144
MET C   3
 None
 1.25A 5wqpA-3qgkA:
undetectable		 5wqpA-3qgkA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 4 GLN C 209
THR C 172
THR C 491
LEU C 506
 None
 1.46A 6f3mB-3qgkC:
undetectable		 6f3mB-3qgkC:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae;
Helicobacter
mustelae) 		3 / 3 MET C 103
GLN C 104
ARG A 165
 None
 0.99A 6fn9A-3qgkC:
undetectable		 6fn9A-3qgkC:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae;
Helicobacter
mustelae) 		3 / 3 MET C 103
GLN C 104
ARG A 165
 None
 1.02A 6fnaB-3qgkC:
undetectable		 6fnaB-3qgkC:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3qgk FUSION OF UREASE
BETA AND GAMMA
SUBUNITS
UREASE SUBUNIT BETA
2
(Helicobacter
mustelae;
Helicobacter
mustelae) 		3 / 3 MET C 103
GLN C 104
ARG A 165
 None
 0.99A 6fnbA-3qgkC:
undetectable		 6fnbA-3qgkC:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 3qgk UREASE SUBUNIT BETA
2
(Helicobacter
mustelae) 		4 / 5 LEU C 194
THR C 172
THR C 170
GLY C 159
 None
None
KCX  C 218 ( 3.4A)
None
 1.15A 6gtqA-3qgkC:
0.0		 6gtqA-3qgkC:
17.58