SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qgm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		4 / 6 THR A 147
GLY A  94
THR A  92
ILE A  99
 None
 0.91A 1gtnD-3qgmA:
undetectable
1gtnE-3qgmA:
undetectable		 1gtnD-3qgmA:
15.73
1gtnE-3qgmA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		5 / 10 GLY A 222
ALA A 217
THR A 225
ILE A 221
ALA A 216
 None
 1.20A 1gtnU-3qgmA:
undetectable
1gtnV-3qgmA:
undetectable		 1gtnU-3qgmA:
15.73
1gtnV-3qgmA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_1
(HMG-COA REDUCTASE)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		4 / 7 VAL A  43
SER A  44
ASN A  46
ASP A  13
 None
 1.19A 1hwiC-3qgmA:
undetectable		 1hwiC-3qgmA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_D_115D3_2
(HMG-COA REDUCTASE)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		4 / 7 VAL A  43
SER A  44
ASN A  46
ASP A  13
 None
 1.18A 1hwiD-3qgmA:
undetectable		 1hwiD-3qgmA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		4 / 6 ALA A  78
TYR A 117
ILE A 145
LEU A 107
 None
 1.00A 1xvaA-3qgmA:
3.4
1xvaB-3qgmA:
3.1		 1xvaA-3qgmA:
21.47
1xvaB-3qgmA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		5 / 10 THR A 163
ILE A 167
GLY A 164
THR A 147
PRO A 178
 None
 1.02A 2y7wB-3qgmA:
1.5		 2y7wB-3qgmA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		5 / 12 PRO A 249
PHE A 253
THR A 233
LEU A 256
VAL A  15
 None
 1.10A 2zifB-3qgmA:
3.9		 2zifB-3qgmA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_2
(PROTEASE)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		5 / 9 ASP A  11
ILE A   9
GLY A 218
VAL A 188
ILE A 189
 CA  A 503 (-2.2A)
None
None
None
None
 1.11A 3ndwB-3qgmA:
undetectable		 3ndwB-3qgmA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		5 / 12 VAL A  90
ILE A 145
VAL A 182
ILE A 189
LEU A 107
 None
 1.34A 4a84A-3qgmA:
undetectable		 4a84A-3qgmA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		5 / 9 MET A 241
GLY A 208
VAL A 228
ASP A  11
VAL A  15
 None
None
None
CA  A 503 (-2.2A)
None
 1.42A 4da6A-3qgmA:
undetectable		 4da6A-3qgmA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		3 / 3 ARG A  59
GLU A  69
ARG A  52
 None
 0.89A 4mwvA-3qgmA:
undetectable		 4mwvA-3qgmA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		4 / 8 ASP A 209
ASP A  11
ASP A 214
ILE A 189
 CA  A 503 (-2.7A)
CA  A 503 (-2.2A)
CA  A 503 ( 4.4A)
None
 1.05A 4xjeA-3qgmA:
undetectable		 4xjeA-3qgmA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		5 / 9 SER A 255
GLY A  26
GLY A  29
LEU A  33
GLU A 261
 None
 1.23A 5vw4A-3qgmA:
undetectable		 5vw4A-3qgmA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 3qgm P-NITROPHENYL
PHOSPHATASE (PHO2)
(Archaeoglobus
fulgidus) 		4 / 6 PHE A  91
LEU A 118
ALA A 137
ASN A 127
 None
 0.96A 6f88A-3qgmA:
undetectable		 6f88A-3qgmA:
20.34