SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3qgu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 5 TRP A 293
ILE A 135
ASP A 248
ASN A 220
 GOL  A 452 (-4.4A)
None
None
None
 1.42A 1kiaD-3qguA:
0.2		 1kiaD-3qguA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 GLY A 330
GLY A 331
VAL A 120
LEU A 335
LEU A 116
 None
 1.01A 1mx1F-3qguA:
undetectable		 1mx1F-3qguA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 THR A 287
GLY A  77
GLY A 285
VAL A 400
ILE A  72
 SO4  A 450 ( 4.6A)
None
None
None
None
 1.15A 2b25B-3qguA:
2.3		 2b25B-3qguA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KQE_A_ADNA1002_1
(APRATAXIN AND
PNK-LIKE FACTOR)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 5 TYR A 407
SER A 164
TYR A 165
ARG A 416
 None
 1.43A 2kqeA-3qguA:
0.0		 2kqeA-3qguA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_E_AG2E671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 7 ILE A  87
LEU A 253
LEU A 340
GLY A 339
 None
GOL  A 452 (-3.8A)
None
None
 0.89A 2qqcD-3qguA:
undetectable
2qqcE-3qguA:
undetectable		 2qqcD-3qguA:
14.25
2qqcE-3qguA:
7.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 8 ALA A 284
SER A 281
GLY A 140
LYS A 142
 GOL  A 452 ( 4.0A)
SO4  A 451 (-3.1A)
SO4  A 451 (-3.4A)
SO4  A 451 (-2.7A)
 0.93A 2vh3B-3qguA:
undetectable		 2vh3B-3qguA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		3 / 3 PRO A 409
GLY A 185
TYR A 191
 None
 0.59A 2vouB-3qguA:
undetectable		 2vouB-3qguA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		3 / 3 PRO A 409
GLY A 185
TYR A 191
 None
 0.60A 2vouC-3qguA:
undetectable		 2vouC-3qguA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 8 GLY A 438
ILE A 393
PHE A 414
PHE A 366
 None
 0.96A 3ko0B-3qguA:
undetectable
3ko0J-3qguA:
undetectable		 3ko0B-3qguA:
12.44
3ko0J-3qguA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK201_1
(PROTEIN S100-A4)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 8 GLY A 438
ILE A 393
PHE A 414
PHE A 366
 None
 0.87A 3ko0K-3qguA:
undetectable
3ko0S-3qguA:
undetectable		 3ko0K-3qguA:
12.44
3ko0S-3qguA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 6 PHE A 361
PHE A 433
TYR A 437
VAL A 415
 None
 1.26A 3lb3A-3qguA:
undetectable		 3lb3A-3qguA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		3 / 3 PRO A 375
SER A 418
ASN A 220
 None
 0.75A 3lslG-3qguA:
undetectable		 3lslG-3qguA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 PHE A 414
GLY A 380
GLY A 404
ALA A 417
SER A  73
 None
 1.28A 3sueD-3qguA:
undetectable		 3sueD-3qguA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 9 ALA A 238
ALA A 270
GLY A 269
ILE A 267
ILE A 264
 None
 1.15A 4eatB-3qguA:
2.0		 4eatB-3qguA:
22.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		4 / 4 LEU A 394
ARG A 432
ILE A 399
ILE A  72
 None
 1.29A 5dzk2-3qguA:
undetectable
5dzkM-3qguA:
undetectable
5dzkN-3qguA:
undetectable		 5dzk2-3qguA:
33.33
5dzkM-3qguA:
17.46
5dzkN-3qguA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 ILE A 244
THR A 263
GLU A 276
ALA A 159
SER A 141
 None
None
None
None
SO4  A 451 (-4.8A)
 1.44A 5iwuA-3qguA:
undetectable		 5iwuA-3qguA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A 335
LEU A 332
GLY A 331
GLY A 330
VAL A 327
 None
 0.88A 5uc1A-3qguA:
undetectable		 5uc1A-3qguA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 LEU A 335
LEU A 332
GLY A 331
GLY A 330
VAL A 327
 None
 0.87A 5uc1B-3qguA:
undetectable		 5uc1B-3qguA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 3qgu LL-DIAMINOPIMELATE
AMINOTRANSFERASE
(Chlamydomonas
reinhardtii) 		5 / 12 ALA A 252
VAL A 120
PHE A 124
GLY A 292
LEU A 335
 GOL  A 452 (-3.5A)
None
GOL  A 452 (-3.6A)
None
None
 0.94A 5x23A-3qguA:
undetectable		 5x23A-3qguA:
21.26